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I-N-Acetyl-L-cysteine CAS:616-91-1
I-N-Acetyl-L-cysteine (NAC) iwuhlobo oluguquliwe lwe-amino acid cysteine. Ihlinzeka ngomthombo we-cysteine futhi ingaguqulwa kalula ibe yi-tripeptide glutathione, i-antioxidant enamandla emzimbeni. I-NAC yaziwa ngezakhiwo zayo ze-antioxidant kanye ne-mucolytic, okwenza ibe usizo ezinhlelweni ezahlukene zezempilo.
Njenge-antioxidant, i-NAC isiza ukuvikela amaseli ekulimaleni okubangelwa ama-free radicals, izinhlobo ze-oxygen ezisabelayo, kanye nobuthi. Iphinde isekele ukwakheka kwe-glutathione, okudlala indima ebalulekile ezinqubweni zokususa ubuthi emzimbeni kanye nokugcina amasosha omzimba aphilile.
I-NAC ihlolwe ngezinzuzo zayo ezingaba khona empilweni yokuphefumula, ikakhulukazi kubantu abanezimo ezifana ne-bronchitis engapheli, i-COPD, kanye ne-cystic fibrosis. Ivame ukusetshenziswa njenge-expectorant ukusiza ekunciphiseni nasekukhululeni i-mucus, okwenza kube lula ukuhlanza imigudu yokuphefumula.
Ngaphezu kwalokho, i-NAC ibonise isithembiso ekusekeleni impilo yesibindi ngokusiza ekususeni izinto ezinobuthi, njenge-acetaminophen, umuthi ovamile wokuqeda ubuhlungu. Kungase futhi kube nemiphumela yokuvikela ekulimaleni kwesibindi okubangelwa ukuphuza utshwala.
Ngaphezu kwezakhiwo zayo zokuvikela ama-antioxidant kanye nokusekela ukuphefumula, i-NAC iye yahlolwa ngezinzuzo zayo ezingaba khona empilweni yengqondo. Ucwaningo oluthile lubonisa ukuthi ingaba nomthelela omuhle ezinkingeni zemizwa, njengokucindezeleka kanye nesifo sokuzikhukhumeza (OCD).
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I-GLYCYL-L-PROLINE CAS: 704-15-4
I-Glycyl-L-proline, eyaziwa nangokuthi i-glycylproline noma i-Gym-Pro, iyi-amino acid derivative equkethe i-amino acid glycine enamathiselwe ku-amino acid L-proline. Iyinhlanganisela yemvelo etholakala ku-collagen, iphrotheni ephethe isakhiwo namandla ezicubu ezahlukene emzimbeni. I-Glycyl-L-proline iye yacwaningwa ngezinzuzo zayo zezempilo ezingaba khona, okuhlanganisa ukukhuthaza impilo yesikhumba, ukunciphisa ukuvuvukala, kanye nokusekela impilo yamalunga namathambo. Iphinde isetshenziswe ekwakhiweni kwezimonyo ngenxa yezakhiwo zayo zokuthambisa kanye nezokulwa ne-antioxidant.
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I-Guanidine Hydrochloride CAS:50-01-1
I-Guanidine hydrochloride iyinhlanganisela yamakhemikhali enefomula yama-molecule i-CH5N3·I-HCl. Iyi-ejenti enamandla ye-chaotropic esetshenziswa kabanzi kwizicelo ze-biochemistry kanye ne-molecular biology.
I-Guanidine hydrochloride ivame ukusetshenziselwa ukwehlisa amaprotheni, ukuphazamisa izakhiwo zamaprotheni, nokuvula amaprotheni ngezinjongo zokuhlanza. Isebenza kahle kakhulu ekuphuleni izibopho ze-hydrogen kanye nokuphazamisa ukusebenzisana okungena-covalent ngaphakathi kwamaprotheni. Lesi sici senza kube usizo ekuncibilikiseni amaprotheni avame ukungancibiliki noma avame ukuhlanganiswa.
Iphinde isetshenziswe njengesiqinisi samaprotheni, ivikele amaprotheni ekuhlanganisweni okungafuneki noma ekugugulekeni ngesikhathi sokuhlolwa okuhlukahlukene kwamakhemikhali kanye ne-biophysical. I-Guanidine hydrochloride ingasiza ekugcineni isakhiwo sendawo kanye nomsebenzi wamaprotheni ngaphansi kwezimo zokuguqulwa kwamaprotheni..
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I-Acetylthiocholine iodide CAS:1866-15-5
I-Acetylthiocholine iodide iyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-substrate ekuhlolweni kwama-enzyme ukukala umsebenzi we-enzyme i-acetylcholinesterase (AChE). I-AChE iyi-enzyme efaka i-acetylcholine kuma-neurotransmitter, isinyathelo esibalulekile ekuqedeni ukudluliselwa kwesignali phakathi kwamaseli ezinzwa.
Uma i-acetylthiocholine iodide isebenza yi-AChE, iqembu le-acetyl liyasuswa, okuholela ekwakhekeni kwama-ion e-thiocholine nama-acetate. I-Thiocholine bese isabela nge-reagent engenambala ebizwa nge-DTNB (5,5′-dithiobis (2-nitrobenzoic acid)) ukuze ikhiqize i-compound ephuzi ebizwa nge-5-thio-2-nitrobenzoate, engalinganiswa nge-spectrophotometric. Izinga lokuthuthukiswa kombala lihambisana ngqo nomsebenzi we-AChE kusampula.
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2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride usawoti ophindwe kabili (21) CAS:67801-08-5
2-Methoxy-4-morpholinobenzenediazonium chloride zinc chloride usawoti ophindwe kabili uyinhlanganisela eqinile yekristalu esetshenziswa njenge-reagent ekwakhiweni kwezinto eziphilayo. Iqukethe i-diazonium cation, ama-chloride anion, kanye nama-zinc cation. Le nhlanganisela inikeza ukuzinza okuthuthukisiwe kanye nokuncibilika, okwenza ifanelekele ukusetshenziswa kwamakhemikhali ahlukahlukene kanye nemithi.
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4,5-Diazafluoren-9-one CAS:50890-67-0
I-4,5-Diazafluoren-9-one iyinhlanganisela yamakhemikhali eyingxenye yesigaba sama-compounds aromatic aheterocyclic. Yakhiwe uhlaka lwe-fluorene olunama-athomu amabili e-nitrogen (i-diaza) kanye ne-athomu ye-oxygen (eyodwa) enamathiselwe ezindaweni ezithile. Ivame ukusetshenziswa njengebhloko yokwakha noma ephakathi kokwenziwa kwezinto eziphilayo, ikakhulukazi ekulungiseleleni ama-compounds ahlukahlukene e-organic, imithi, kanye nodayi. Isakhiwo sayo kanye nokusebenza kwayo kwenza kube ithuluzi eliwusizo lokudala izakhiwo zama-molecule ahlukahlukene kanye namaqembu asebenzayo.
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I-Tapso Sodium CAS: 105140-25-8 Intengo Yomkhiqizi
i-3-[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid,KuyimiI-sa zwitterionic buffering agent ngesimo sikasawoti we-sodium. Ivame ukusetshenziswa ekuhlolweni kwe-biochemical kanye ne-molecular biology ukuze kugcinwe i-pH ezinzile ezixazululweni.It incibilika kakhulu emanzini futhi ine-pKa eseduze ne-pH yemvelo, okwenza ifaneleke ezinhlotsheni eziningi zezicelo ezifana nokuhlanzwa kwamaprotheni, ukuhlolwa kwama-enzyme, ukukhuliswa kwamaseli, kanye ne-electrophoresis. Isakhiwo sayo samakhemikhali esiyingqayizivele kanye nokuhambisana kwayo nezinhlelo zezinto eziphilayo kuyenza ibe yingxenye ebalulekile kumaphrothokholi ahlukahlukene elebhu.
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Usawoti we-4-Nitrophenyl phosphate di(tris) CAS:68189-42-4
Usawoti i-4-Nitrophenyl phosphate di(tris) usawoti uyinhlanganisela yamakhemikhali esetshenziswa ocwaningweni lwe-biochemical kanye nokuxilongwa. Uvame ukusetshenziswa njengesisekelo sokuhlolwa kwe-enzyme ye-alkaline phosphatase. Losawoti, uma ufakwa i-hydrolyzed yi-alkaline phosphatase, ukhiqiza umkhiqizo ophuzi ongalinganiswa kalula nge-spectrophotometric. Lokhu kusabela kusetshenziswa kabanzi ezinhlotsheni ezahlukene zokusebenza, kufaka phakathi ukuhlolwa kwe-immunosorbent okuxhunywe yi-enzyme (ELISAs) kanye nokutholwa komsebenzi we-phosphatase. Ukuqina kombala ophuzi kuhambisana ngqo nomsebenzi we-enzyme, okuvumela ukulinganiswa okunembile kwamazinga e-alkaline phosphatase kumasampula ebhayoloji. Usawoti i-4-Nitrophenyl phosphate di(tris) uzinzile, uyancibilika emanzini, futhi uzwela kakhulu, okwenza kube ukukhetha okuthandwayo kokuhlolwa kwe-enzyme ocwaningweni lwebhayoloji nolwezokwelapha.
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I-Nitrotetrazolium blue chloride CAS:298-83-9
I-Nitrotetrazolium blue chloride, eyaziwa nangokuthi i-NBT noma i-NBT-Cl, iyinhlanganisela yamakhemikhali evame ukusetshenziswa ekuhlolweni kwezinto eziphilayo kanye nezamakhemikhali. Iyimpuphu ephuzi ephuzi encibilikayo emanzini.
I-NBT ivame ukusetshenziswa njengesibonakaliso sokubona ukuba khona kwama-superoxide radicals noma ama-enzyme awakhiqizayo. Ishintsha umbala uma incishiswa ama-superoxide radicals, ishintsha isuka kophuzi iye ku-deep blue formazan precipitate. Lokhu kusabela kuvame ukusetshenziswa ezivivinyweni zokufunda ukucindezeleka kwe-oxidative, ukuphefumula kwamaseli, kanye nomsebenzi wama-enzyme.
I-NBT ivame ukusetshenziswa ezindleleni ezahlukene, njengokunciphisa i-nitroblue tetrazolium, ukubona ngeso lengqondo ukukhiqizwa kwe-superoxide emaseli nasezicutshini. Iphinde yasetshenziswa ku-immunohistochemistry kanye ne-histochemistry ukuthola nokuthola amanye ama-enzyme kanye nezingxenye zamaseli.
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I-NSP-AS CAS:211106-69-3 Intengo Yomkhiqizi
I-compound 3-[9-(((3-(carboxypropyl)[4-Methxylphenyl]sulfonyl)aMine)carboxyl]-10-acridiniuMyl)-1-propanesulfonate usawoti wangaphakathi iyi-molecule eyinkimbinkimbi equkethe ingxenye ye-acridinium enamathele kusawoti wangaphakathi we-propanesulfonate. Iqukethe iqembu le-carboxypropyl, iqembu le-4-Methxylphenylsulfonyl, kanye neqembu le-amine. Le compound cishe yenzelwe ukusetshenziswa okuthile ezindaweni ezifana ne-chemistry, imithi, noma ucwaningo.
Ngaphezu kwalokho, i-NAC ibonise isithembiso ekusekeleni impilo yesibindi ngokusiza ekususeni izinto ezinobuthi, njenge-acetaminophen, umuthi ovamile wokuqeda ubuhlungu. Kungase futhi kube nemiphumela yokuvikela ekulimaleni kwesibindi okubangelwa ukuphuza utshwala.
Ngaphezu kwezakhiwo zayo zokuvikela ama-antioxidant kanye nokusekela ukuphefumula, i-NAC iye yahlolwa ngezinzuzo zayo ezingaba khona empilweni yengqondo. Ucwaningo oluthile lubonisa ukuthi ingaba nomthelela omuhle ezinkingeni zemizwa, njengokucindezeleka kanye nesifo sokuzikhukhumeza (OCD).
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I-L-Leucine p-nitroanilide hydrochloride CAS:16010-98-3
I-L-Leucine p-nitroanilide hydrochloride iyinhlanganisela yamakhemikhali eyingxenye yeqembu lezinto eziphuma ku-p-nitroanilide. Iyimpuphu yekristalu emhlophe kuya kwemhlophe evame ukusetshenziswa ocwaningweni lwe-biochemical kanye nokuhlolwa kwama-enzyme.
I-L-Leucine p-nitroanilide hydrochloride ivame ukusetshenziswa njenge-substrate ukukala umsebenzi wama-enzyme afana nama-protease nama-peptidases. Lapho la ma-enzyme ehlukana i-L-Leucine p-nitroanilide hydrochloride, ikhipha i-p-nitroaniline, engatholakala nge-spectrophotometric. Izinga lokushintsha kombala lilingana ngqo nomsebenzi we-enzyme, okuvumela ukubalwa komsebenzi we-enzyme kumasampula ebhayoloji.
Le nhlanganisela iyancibilika emanzini futhi ingancibilika kalula ezixazululweni ezifanele ze-buffer ukuze isetshenziswe ekuhlolweni kwe-enzyme. Kubalulekile ukugcina i-L-Leucine p-nitroanilide hydrochloride endaweni epholile neyomile ukuze ihlale izinzile.
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I-Guanidine Thiocyanate Sulfate CAS:593-84-0
I-Guanidine thiocyanate sulfate iyinhlanganisela yamakhemikhali etholakala kuma-ion e-guanidine, thiocyanate, kanye ne-sulfate. Ivame ukusetshenziswa ocwaningweni lwe-biology yamangqamuzana kanye ne-biochemistry njenge-ejenti ye-chaotropic.
I-Guanidine thiocyanate sulfate ivame ukusetshenziswa kumaphrothokholi okuhlukaniswa kwe-DNA ne-RNA ukuphazamisa ulwelwesi lwamaseli kanye namaprotheni aqhekekile, okuvumela ukukhishwa kahle kwama-nucleic acid. Kuyasiza ekuncibilikisweni kwe-DNA ne-RNA, okuvumela ukuhlukaniswa kwazo nokuhlanzwa kwazo kumasampula ahlukahlukene ebhayoloji.
Ngenxa yezakhiwo zayo ze-chaotropic, i-guanidine thiocyanate sulfate isiza ekuphuleni i-hydrogen bonding kanye nokunye ukusebenzisana okungena-covalent, okwenza kube lula ukuhlukaniswa kwama-nucleic acid kumaprotheni, ama-lipid, nezinye izingxenye zamaseli. Iphinde isize ekuvimbeleni umsebenzi we-RNase, iqinisekise ubuqotho nobumsulwa bama-nucleic acid akhishwe..
