I-Acetylthiocholine iodide CAS:1866-15-5

I-Acetylthiocholine iodide iyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-substrate ekuhlolweni kwama-enzyme ukukala umsebenzi we-enzyme i-acetylcholinesterase (AChE). I-AChE iyi-enzyme efaka i-acetylcholine kuma-neurotransmitter, isinyathelo esibalulekile ekuqedeni ukudluliselwa kwesignali phakathi kwamaseli ezinzwa.

Uma i-acetylthiocholine iodide isebenza yi-AChE, iqembu le-acetyl liyasuswa, okuholela ekwakhekeni kwama-ion e-thiocholine nama-acetate. I-Thiocholine bese isabela nge-reagent engenambala ebizwa nge-DTNB (5,5′-dithiobis (2-nitrobenzoic acid)) ukuze ikhiqize i-compound ephuzi ebizwa nge-5-thio-2-nitrobenzoate, engalinganiswa nge-spectrophotometric. Izinga lokuthuthukiswa kombala lihambisana ngqo nomsebenzi we-AChE kusampula.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

Ukulinganiswa komsebenzi we-acetylcholinesterase (AChE): I-Acetylthiocholine iodide ivame ukusetshenziswa njenge-substrate ekuhlolweni kwe-enzyme ukukala umsebenzi we-AChE. I-AChE iyi-enzyme e-hydrolyzes i-acetylcholine, futhi ngokulinganisa umsebenzi wayo, abacwaningi bangahlola umsebenzi we-cholinergic kanye nemiphumela yezidakamizwa, ubuthi, noma izifo ku-AChE.

Ithuluzi lokuxilonga ezinkingeni zokuwohloka kwemizwa: Ukungasebenzi kahle kwe-AChE kubonakala ezifweni eziningana zokuwohloka kwemizwa, okuhlanganisa nesifo i-Alzheimer's. Ukulinganiswa komsebenzi we-AChE kusetshenziswa i-acetylthiocholine iodide kungasiza ekuxilongeni nasekuqapheni izifo ezinjalo.

Izifundo zobuthi: I-Acetylthiocholine iodide isetshenziswa nasezifundweni zobuthi ukuhlola imiphumela yamakhemikhali noma ubuthi emsebenzini we-AChE. Amakhemikhali athile, njenge-organophosphate kanye ne-carbamate insecticide, angavimbela umsebenzi we-AChE, okuholela emiphumeleni yobuthi. I-Acetylthiocholine iodide inganikeza ukuqonda ngobuthi kanye nezindlela zokusebenza kwala ma-compound.

Ukuhlolwa kwezithibi ze-AChE: I-Acetylthiocholine iodide isetshenziswa ekutholakaleni nasekuthuthukisweni kwemithi ukuhlola nokuhlonza izithibi ze-AChE ezingaba khona. Izithibi ze-AChE zingaba usizo ekwelapheni izimo ezahlukahlukene, okuhlanganisa nesifo i-Alzheimer's.

Ukuthuthukiswa kwama-biosensor: I-Acetylthiocholine iodide, kanye ne-AChE, isetshenziswa ekuthuthukisweni kwama-biosensor okuthola i-acetylcholine. Lawa ma-biosensor athola ukusetshenziswa ezindaweni ezifana nokuqapha indawo kanye nokuxilongwa kwemitholampilo.

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C7H16INOS
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe
Inombolo ye-CAS	1866-15-5
Ukupakisha	Encane futhi enkulu
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.