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I-Beta-Amylase CAS:9000-91-3 Intengo Yomkhiqizi
I-Beta-amylase iyi-enzyme edlala indima ebalulekile ekugayweni kwama-carbohydrate, ikakhulukazi ekuqhekekeni noma ekugayweni kwama-molecule esitashi. Ikhuthaza ukuqhekeka kwezibopho ze-α-1,4-glycosidic esitashi, ikhulule i-maltose kanye neyunithi encane ebizwa ngokuthi i-limit dextrin.
Le enzyme ikhiqizwa ezintweni eziphilayo ezahlukahlukene, okuhlanganisa izitshalo, amabhaktheriya kanye nesikhunta, futhi ivame ukusetshenziswa ezimbonini ezifana nokukhiqiza ubhiya, ukubhaka kanye nokukhiqizwa kukaphethiloli.
Ekuphekeni, i-beta-amylase idlala indima ebalulekile ekuguqulweni kwezitashi ezinhlamvini ezifakwe ku-malted zibe ushukela ovundayo ngesikhathi senqubo yokuxubha, okufaka isandla ekukhiqizweni kotshwala ngemvubelo. Ekubhakeni, kusiza ukuphula izitashi zibe ushukela, okufaka isandla ekuthuthukisweni kokunsundu kanye nokunambitheka kwezinto ezibhakiwe. Ekukhiqizweni kukaphethiloli we-biofuel, i-beta-amylase isetshenziswa ekufakweni kwe-biomass esekelwe ku-starch ukuze kutholakale ushukela ovundayo osetshenziselwa ukukhiqizwa kwe-ethanol.
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I-Bromelain evela ku-Pineapple STEM CAS:37189-34-7
I-Bromelain iyinhlanganisela yama-enzyme atholakala esiqwini sesitshalo sikaphayinaphu (i-Ananas comosus). Yakhiwa ngokuyinhloko ama-protease, angama-enzyme aphula amaprotheni. I-Bromelain ibilokhu isetshenziswa amakhulu eminyaka kwezokwelapha zendabuko njengomuthi wemvelo wezimo ezahlukene zempilo.
Ngenxa yezakhiwo zayo zokugaya amaprotheni, i-bromelain ivame ukusetshenziswa njengesiza sokugaya ukudla, isiza ekuthuthukiseni ukuqhekeka nokumuncwa kwamaprotheni ohlelweni lokugaya ukudla. Iphinde yacwaningwa ngemiphumela yayo yokulwa nokuvuvukala kanye nezinzuzo ezingaba khona zokunciphisa ukuvuvukala, ukuklwebheka, kanye nobuhlungu.
Ngaphezu kwezakhiwo zayo zokugaya ukudla kanye nokulwa nokuvuvukala, i-bromelain iye yahlolwa ukuthi inamandla yini kwezinye izinhlelo zokwelapha ezahlukahlukene, okuhlanganisa ukuphulukiswa kwamanxeba, ukusekelwa kwamasosha omzimba, kanye nempilo yokuphefumula.
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I-Calpain Inhibitor IV CAS:133407-82-6
I-Calpain Inhibitor IV uhlobo lomuthi oluhlasela futhi luvimbele ngqo umsebenzi we-enzyme i-calpain. I-Calpain iyi-enzyme ye-protease encike ku-calcium edlala indima ezinqubweni ezahlukahlukene zamaseli, okuhlanganisa ukusabalalisa amaseli, i-apoptosis, kanye nokuvuselelwa kwe-cytoskeletal.
Ngokuvimbela i-calpain, i-Calpain Inhibitor IV isiza ukuvimbela ukusebenza ngokweqile nokungalawuleki kwale enzyme, okungaholela ekulimaleni kwamaseli kanye nokungasebenzi kahle kwawo. Lokhu kuvinjelwa kungaba wusizo ezimweni lapho ukusebenza ngokweqile kwe-calpain kuhlotshaniswa khona, njengezifo ze-neurodegenerative ezifana ne-Alzheimer's kanye ne-Parkinson's, ukulimala kwe-ischemic, noma izimo zokuwohloka kwemisipha.
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I-Carboxypeptidase B CAS:9025-24-5
I-Carboxypeptidase B iyi-enzyme edlala indima ebalulekile ekugayweni kwamaprotheni kanye ne-metabolism. Ngokukhethekile, ivuselela i-hydrolysis yezibopho ze-peptide ekugcineni kwe-C-terminal yamaprotheni, okuholela ekususweni kwama-amino acid ngamanye.
I-Carboxypeptidase B ikhethekile kakhulu kuma-amino acid ayisisekelo, njenge-lysine ne-arginine, futhi isebenza kahle kakhulu ekususeni lezi zinsalela. Ivame ukutholakala ekukhishweni kwe-pancreatic futhi ihilelekile esigabeni sokugcina sokugaya amaprotheni emathunjini amancane.
Le enzyme isetshenziswa nasezinhlelweni ezahlukene zelebhu, okuhlanganisa ukulandelana kwamaprotheni, ukwakheka kwama-peptide, kanye nokuhlaziywa kwamaprotheni. Amandla e-carboxypeptidase B okuhlukanisa ngqo ama-amino acid e-C-terminal amaprotheni ayenza ibe ithuluzi eliwusizo lokufunda isakhiwo nomsebenzi wamaprotheni.
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I-Carboxypeptidase, i-dipeptidyl, i-A CAS:9015-82-1
I-Carboxypeptidase iyi-enzyme ekhuthaza i-hydrolysis (ukuqhekeka) kwezibopho ze-peptide ekugcineni kwe-carboxyl (C-terminal) yama-peptide namaprotheni. Isiza ekugayweni nasekucutshungulweni kwamaprotheni ngokususa ama-amino acid ngamanye ekugcineni kochungechunge lwe-peptide. Ama-Carboxypeptidase ahlukaniswe ngezinhlobo ezimbili: ama-exopeptidase, asusa ama-amino acids ngalinye ngesikhathi ekugcineni kwe-C-terminal, kanye nama-endopeptidase, ahlukanisa izibopho ze-peptide ngaphakathi kochungechunge lwe-peptide. Lawa ma-enzyme adlala indima ebalulekile ezinqubweni ezahlukene zebhayoloji, okuhlanganisa i-metabolism yamaprotheni, ukulawulwa kwama-hormone, kanye nokulawulwa komsebenzi we-enzymatic.
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I-Coenzyme A i-sodium salt hydrate I-CAS:55672-92-9
I-Coenzyme A sodium salt hydrate iwuhlobo lwe-Coenzyme A (CoA) oluncibilika emanzini, i-coenzyme ebalulekile ehilelekile ezindleleni ezahlukene ze-metabolic. Idlala indima ebalulekile ekuqhekekeni kwamafutha, ama-carbohydrate, namaprotheni, kanye nokuhlanganiswa kwama-molecule abalulekile njenge-fatty acids ne-cholesterol. I-Coenzyme A sodium salt hydrate ivame ukusetshenziswa ocwaningweni lwe-biochemical kanye ne-pharmaceutical njengesengezo sokutadisha i-metabolism yamaseli kanye nezinqubo ezihlobene.
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I-5-Nitro-1,10-phenanthroline CAS:4199-88-6
I-5-Nitro-1,10-phenanthroline iyinhlanganisela yamakhemikhali enefomula yama-molecule i-C12H6N4O2. Ingowomndeni wezinto eziphuma ku-phenanthroline futhi iqukethe iqembu le-nitro (-NO2) elixhunywe endaweni engu-5 yesistimu yendandatho ye-phenanthroline.
Le nhlanganisela yaziwa ngekhono layo lokwakha ama-complex azinzile ngama-ion ensimbi, ikakhulukazi ama-ion ensimbi aguqukayo. Iqembu le-nitro lithuthukisa izakhiwo zalo zokwakheka futhi lilenze libe usizo ezinhlelweni ezahlukahlukene ezifana ne-analytical chemistry, i-catalysis, kanye ne-coordination chemistry.
I-5-Nitro-1,10-phenanthroline isetshenziswe njenge-chelator, okusho ukuthi yakha izibopho ezizinzile nama-ion ensimbi ngokunikela ngama-electron amabili ahlukene. Lokhu kuvumela ukulawulwa okunembile kanye nokuphathwa kwezindawo zokuxhumanisa i-metal-ion.
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I-Acetyl coenzyme A usawoti we-sodium I-CAS:102029-73-2
Usawoti we-sodium i-Acetyl coenzyme A (acetyl-CoA) uyi-derivative yokwenziwa ye-acetyl-CoA. Ngokuvamile isetshenziswa ocwaningweni lwelabhorethri kanye nezifundo ze-biochemical.
Ukusetshenziswa okuyinhloko kosawoti we-sodium we-acetyl-CoA kusezifundweni ze-metabolism yamaseli, ikakhulukazi ekuphenyeni indima ye-acetyl-CoA ezindleleni ezahlukahlukene ze-metabolism. I-Acetyl-CoA isebenza njengesandulela sokwenziwa kwama-fatty acid, i-cholesterol, kanye nemizimba ye-ketone, kanye nokudlala indima ebalulekile ekukhiqizweni kwamandla ngomjikelezo we-citric acid (owaziwa nangokuthi umjikelezo we-Krebs).
Ngaphezu kwalokho, i-acetyl-CoA ihilelekile ekuhlanganiseni amaprotheni, i-DNA, nama-histone, okungathinta ukubonakaliswa kwezakhi zofuzo kanye nokuguqulwa kwe-chromatin. Ngakho-ke, usawoti we-acetyl-CoA sodium ungasetshenziswa ezifundweni ezigxile kulezi zinguquko ze-epigenetic kanye nomthelela wazo ekusebenzeni kweseli.
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I-Puromycin dihydrochloride CAS: 58-58-2 Intengo Yomkhiqizi
I-Puromycin dihydrochloride iyi-antibiotic enamandla evame ukusetshenziswa ocwaningweni lwe-molecular biology kanye ne-cell biology. Ivimbela ukwakheka kwamaprotheni ngokubangela ukuqedwa kwangaphambi kwesikhathi kokwakheka kwamaprotheni ngesikhathi sokuhumusha. I-Puromycin iyasebenza ngokumelene namaseli e-prokaryotic kanye ne-eukaryotic futhi iwusizo kakhulu ekukhetheni nasekuhlukaniseni amaseli aguqulwe izakhi zofuzo noma afakwe i-gene yokumelana ne-puromycin. Ngokuvamile isetshenziswa ezindaweni zelebhu ukutadisha ukubonakaliswa kwezakhi zofuzo, ukwakheka kwamaprotheni, kanye nokukhiqiza imigqa yamaseli ezinzile ngokuguqulwa kwezakhi zofuzo ezithile.
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I-Acetylcholinesterase CAS:9000-81-1
Ama-anticholinesterase ayiqembu lezidakamizwa noma amakhemikhali avimbela umsebenzi we-enzyme i-acetylcholinesterase. I-Acetylcholinesterase inesibopho sokuphula i-neurotransmitter acetylcholine emzimbeni. Ngokuvimbela le enzyme, ama-anticholinesterase andisa amazinga e-acetylcholine, okuholela ekwandeni komsebenzi we-cholinergic ezinhlelweni zezinzwa eziphakathi nezingaphandle.
Ukusetshenziswa okuyinhloko kwezokwelapha kwama-anticholinesterases ekwelapheni izifo zezinzwa ezifana nesifo i-Alzheimer's kanye ne-myasthenia gravis. Esifweni i-Alzheimer's, le mithi ihlose ukuthuthukisa ukudluliselwa kwe-cholinergic neurotransmission futhi inciphise ukwehla kwengqondo. Ku-myasthenia gravis, ama-anticholinesterase asiza ekuthuthukiseni ukudluliselwa kwemisipha kanye namandla emisipha.
Okunye ukusetshenziswa kwama-anticholinesterase kufaka phakathi ukuxilongwa nokwelashwa kobuthi be-anticholinergic, ikakhulukazi kusuka kuma-insecticide athile noma ama-nerve agents. Lezi zinto zingabangela ukukhuthazwa ngokweqile kwama-receptor e-muscarinic kanye ne-nicotinic, okuholela ezimpawini ezifana nobuthakathaka bemisipha, ukuthuthumela, kanye nokucindezeleka kokuphefumula. Ama-anticholinesterase angaguqula le miphumela ngokwandisa amazinga e-acetylcholine kanye nokuncintisana nezinto ezinobuthi.
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I-Rapamycin evela ku-Streptomyces hygroscopicus CAS:53123-88-9
I-Rapamycin iyinhlanganisela yemvelo ehlukaniswe nebhaktheriya i-Streptomyces hygroscopicus. Inemisebenzi eminingi yebhayoloji futhi yaziwa kakhulu ngezakhiwo zayo zokucindezela amasosha omzimba kanye nokulwa nomdlavuza.
Ekuqaleni yatholakala njenge-antifungal agent, i-rapamycin itholakale inezakhiwo ezinamandla zokucindezela amasosha omzimba, okwenza ibe usizo ekufakweni kwezitho zomzimba ukuze kuvinjelwe ukwenqatshwa. Lokhu ikwenza ngokuvimbela ukusebenza nokwanda kwama-T-cell, okuyingxenye ebalulekile yempendulo yomzimba.
Ngaphezu kwalokho, i-rapamycin ibonise imiphumela ethembisayo ekwelapheni izinhlobo ezahlukene zomdlavuza. Isebenza ngokuvimbela iphrotheni ebizwa ngokuthi i-mTOR (i-mammalian target ye-rapamycin), edlala indima ebalulekile ekukhuleni nasekuhlukaneni kwamaseli. Ngokuvimba i-mTOR, i-rapamycin isiza ukulawula ukukhula okungalawulwa kwamaseli omdlavuza.
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I-Acylase evela kuhlobo lwe-Aspergillus CAS:9012-37-7
I-Acylase iyi-enzyme ekhiqizwa izinhlobo ezahlukene ezivela kuhlobo lwe-Aspergillus, okuhlanganisa i-Aspergillus oryzae kanye ne-Aspergillus niger. Le enzyme ingeyemindeni yama-hydrolases futhi ihilelekile ekufakweni kwe-hydrolysis kwama-acyl compounds.
Ama-Acylase adlala indima ebalulekile ezinqubweni ezahlukahlukene ze-biochemical, ikakhulukazi ekusetshenzisweni kwe-metabolism yamakhemikhali e-organic. Avuselela ukuqhekeka kwamaqembu e-acyl kusuka ku-substrate, ngokuvamile esebenzisa amanzi njenge-co-reactant. Lokhu kusabela kwe-enzyme kwaziwa ngokuthi i-acyl hydrolysis.
Ama-Acylase avela kuhlobo lwe-Aspergillus afundwe kabanzi futhi asetshenziswa ekusetshenzisweni kwe-biotechnology. Abonise amandla amakhulu ekukhiqizweni kwamakhemikhali ahlukahlukene ayigugu njenge-amino acid, ama-antibiotic, kanye nezinye izinto ezisetshenziswayo kwezokwelapha.
