I-Coenzyme A i-sodium salt hydrate I-CAS:55672-92-9

Ukukhiqizwa kwamandla: I-Coenzyme A iyisakhi esibalulekile emjikelezweni we-citric acid (owaziwa nangokuthi umjikelezo we-Krebs) kanye nezindlela ze-beta-oxidation, ezibangela ukukhiqiza amandla avela kumafutha, ama-carbohydrate, kanye namaprotheni. Ngokusebenza njengomthwali wamaqembu e-acetyl, i-Coenzyme A idlala indima ebalulekile ekukhiqizeni i-adenosine triphosphate (ATP), uhlobo lwemali lwamandla oluyinhloko lwamaseli.

Ukuguqulwa kwamafutha emzimbeni: I-Coenzyme A ibandakanyeka ekwakhiweni nasekuqhekekeni kwama-fatty acid. Isebenza njenge-coenzyme yama-enzyme afana ne-acetyl-CoA carboxylase, ebangela ukwakheka kwama-fatty acid, kanye ne-fatty acyl-CoA dehydrogenase, ebandakanyeka ekwakhiweni kwama-fatty acids. I-Coenzyme A ibandakanyeka futhi ekwakhiweni kwe-cholesterol.

Ukuguqulwa kwe-amino acid: I-Coenzyme A inegalelo ekuguqulweni kwe-amino acid ngokubandakanyeka ekuguqulweni kwe-transamination kanye ne-oxidative deamination reactions. Isiza ukuguqula ama-amino acid abe yi-acetyl-CoA noma ezinye izinto ezisetshenziswa ekukhiqizeni amandla noma ekuhlanganiseni i-biosynthesis.

Ukususa Ubuthi: I-Coenzyme A ibalulekile enqubweni ebizwa ngokuthi i-acylation, esiza ekususeni ubuthi ezintweni eziyingozi, njengezidakamizwa nama-xenobiotic. Kuyasiza ukuguqula lobu buthi bube yizinhlobo ezincibilika emanzini ezingakhishwa kalula ngumzimba.