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I-NSP-AS CAS:211106-69-3 Intengo Yomkhiqizi
I-compound 3-[9-((3-(carboxypropyl))[4-Methxylphenyl]sulfonyl)aMine)carboxyl]-10-acridiniuMyl)-1-propanesulfonate usawoti wangaphakathi i-molecule eyinkimbinkimbi ehlanganisa i-acridinium moiety exhunywe ku-propanesulfonate. usawoti wangaphakathi.Iqukethe iqembu le-carboxypropyl, iqembu le-4-Methxylphenylsulfonyl, neqembu le-amine.Le nhlanganisela kungenzeka ihlanganiselwe izinhlelo zokusebenza ezithile ezindaweni ezifana nekhemistri, ezemithi, noma ucwaningo.
Ngaphezu kwalokho, i-NAC ibonise isithembiso ekusekeleni impilo yesibindi ngokusiza ekukhipheni izinto ezinobuthi, njenge-acetaminophen, isidambisi sobuhlungu esivamile.Kungase futhi kube nemiphumela yokuzivikela ekulimaleni kwesibindi okubangelwa ukuphuza utshwala.
Ngaphezu kwezakhiwo zayo zokusekela i-antioxidant nokuphefumula, i-NAC iye yahlolwa ngezinzuzo zayo ezingaba khona empilweni yengqondo.Olunye ucwaningo lubonisa ukuthi kungase kube nomthelela omuhle ezinkingeni zemizwa, njengokucindezeleka kanye nesifo esicindezelayo (OCD).
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I-Tapso Sodium CAS:105140-25-8 Intengo Yomkhiqizi
3--[N-Tris(hydroxymethyl)methylamino]-2-hydroxypropanesulfonic acid,Kuyimii-agent ye-zwitterionic buffering esesimweni sosawoti we-sodium.Ivamise ukusetshenziswa ekuhlolweni kwebhayoloji yamangqamuzana ezinto eziphilayo ukuze kugcinwe i-pH ezinzile ezisombululweni.It incibilika kakhulu emanzini futhi ine-pKa esondelene ne-pH yokuphila, okuyenza ifanelekele uhla olubanzi lwezinhlelo zokusebenza ezifana nokuhlanzwa kwamaprotheni, ukuhlolwa kwama-enzyme, isiko lamaseli, kanye ne-electrophoresis.Isakhiwo sayo samakhemikhali esiyingqayizivele kanye nokuhambisana nezinhlelo zebhayoloji kuyenza ibe yingxenye ebalulekile kuzivumelwano ezihlukahlukene zaselabhorethri.
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I-NSP-SA-NHS CAS:199293-83-9 Intengo Yomkhiqizi
I-NSP-SA-NHS iyinhlanganisela ehlanganisa i-N-succinimidyl-6-(3′-pyridyldithio)hexanoate (NSP) kanye ne-N-hydroxysuccinimide (NHS).Ivamise ukusetshenziswa njenge-ejenti exhumanisayo ekuphenduleni kwe-bioconjugation, ikakhulukazi ukuhlanganisa ama-peptide, amaprotheni, noma amanye ama-amine ane-amine ezindaweni noma kwamanye ama-molecule.I-NSP moiety ivumela ukwakheka kwebhondi ye-thioester ezinzile ne-molecule eqondiwe, kuyilapho i-NHS moiety ivumela ukusabela okulandelanayo nama-amine ayinhloko.I-NSP-SA-NHS isetshenziswa kabanzi ocwaningweni oluhlukahlukene nasezinhlelweni ze-biomedical, okuhlanganisa ukulungiswa kokuhlolwa kwamasosha omzimba, ukulebula ama-antibody, izifundo zokusebenzisana kwamaprotheni-protein, kanye nokunganyakaziswa kwamaprotheni.
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I-TAPSO CAS:68399-81-5 Intengo Yomkhiqizi
I-TAPSO (3--[N-tris(hydroxymethyl)methyl]amino]-2-hydroxypropanesulfonic acid) iyibhafa ye-zwitterionic evamise ukusetshenziswa ocwaningweni lwebhayoloji nolwe-biochemical.Kuyi-ejenti esebenzayo yokubhafa ene-pKa eseduze ne-pH yezemvelo, okuyenza ifaneleke ukugcina i-pH ezinzile ekuhlolweni kwebhayoloji.I-TAPSO ivame ukusetshenziswa ekuhlanzeni amaprotheni, ekuhlolweni kwe-enzyme, isiko lamaseli, kanye nezicelo ze-electrophoresis.Ukuncibilika kwayo okuphezulu kwamanzi kanye nokuphazamiseka okuphansi kwezinqubo zebhayoloji kuyenza ibe ukukhetha okudumile emphakathini wesayensi.I-TAPSO yaziwa ngomthelela wayo omncane emsebenzini we-enzyme futhi ivamise ukusetshenziswa njengenye indlela kwamanye ama-ejenti agcina imali njenge-Tris noma amabhafa e-phosphate.
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TAPS Sodium usawoti CAS: 70331-82-7
Usawoti we-sodium we-TAPS, owaziwa nangokuthi i-N-(Tris(hydroxymethyl)methyl)-2-aminoethanesulfonic acid sodium salt, i-ejenti eguquguqukayo ehlukahlukene kanye nesilawuli se-pH.Isetshenziswa kakhulu ocwaningweni lwebhayoloji namakhemikhali, kwezemithi, nasekuhloleni izifo.I-TAPS-Na iyinhlanganisela ye-zwitterionic esiza ukugcina i-pH ezinzile ezixazululweni, iyenze ifanele ububanzi bezimo zokuhlola.Izicelo zayo zifaka isiko lamaseli, ucwaningo lwamaprotheni, i-electrophoresis, ukuhlanganiswa kwamakhemikhali, nokwakheka kwemithi.I-TAPS-Na iwuhlobo oluncibilikayo noluzinzile lwe-TAPS okulula ukuluphatha nokulusebenzisa ezixazululweni ezinamanzi.
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2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniumM-9-carboxylate 4′-NHS Ester CAS:194357-64-7
I-2',6'-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate 4'-NHS ester iyinhlanganisela yamakhemikhali enesakhiwo esiyinkimbinkimbi samangqamuzana.Iqukethe iqembu le-sulfopropylacridinium kanye neqembu elisebenzayo le-carboxylate ester.Ukuba khona kwe-ester moiety kubonisa ukuthi iyasebenza futhi ingasetshenziswa njengelebula noma i-ejenti eshintshayo yama-biomolecules.
Iqembu lenhlanganisela ye-sulfopropylacridinium liphakamisa ukuthi lingase libe nokusetshenziswa okungase kube khona ekuhlolweni okusekelwe ku-fluorescence, lapho lingasetshenziswa khona njenge-fluorescent probe noma udayi ukuze kutholwe futhi kuhlaziywe ama-biomolecules.Kungase futhi kube nokubaluleka ezifundweni zezinqubo zamaselula, njengokusayina kwe-calcium ye-intracellular.
Ukufakwa kweqembu le-ester le-NHS kubonisa ukuthi lingasabela ngama-amine ayinhloko, njengalawo atholakala kumaprotheni noma ama-peptide, ukuze enze izibopho eziqinile ze-amide.Lokhu kuphinda kusebenze kuyenza ibe wusizo ezinhlelweni zokusebenza ze-bioconjugation, lapho ingasetshenziswa ukulebula noma ukuguqula ama-biomolecules namanye ama-molecule asebenzayo, njenge-fluorophores noma omaka.
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I-TRIS-Acetate CAS:6850-28-8 Intengo Yomkhiqizi
I-TRIS-Acetate, i-buffer evame ukusetshenziswa ekuhlolweni kwebhayoloji ne-biochemical.Kuyinhlanganisela ye-Tris base ne-acetic acid, okuholela esixazululweni esizinzile se-pH esisetshenziselwa ukulawula nokugcina uhla lwe-pH olufunekayo lwezinhlelo zokusebenza ezihlukahlukene.I-TRIS-Acetate iwusizo ikakhulukazi ocwaningweni lwe-DNA ne-RNA, njengoba inikeza indawo efanelekile yemisebenzi ye-enzyme, i-electrophoresis, ne-gel electrophoresis.Isiza ukugcina ukuzinza nobuqotho be-nucleic acid phakathi nezinqubo ezihlukahlukene, njengokulandelana kwe-DNA, i-polymerase chain reaction (PCR), kanye ne-agarose gel electrophoresis. , ukukhishwa kwe-membrane amaprotheni, nokuhlolwa kwesiko lamaseli.Umthamo wayo oguquguqukayo wokubhafa uwenza ube yithuluzi elibalulekile ezindaweni eziningi zocwaningo lwesayensi, oqinisekisa izimo ezikahle zokusabela kwebhayoloji nokugcina ukuqina kwama-enzyme namaprotheni.
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3-(N-tosyl-L-alanyloxy)indole CAS:75062-54-3
I-3-(N-tosyl-L-alanyloxy) i-indole iyinhlanganisela yamakhemikhali enefomula ye-molecular C20H20N2O4S.Ivamise ukusetshenziswa njengebhlokhi yokwakha noma i-intermediate ku-organic synthesis.Inhlanganisela ifaka uhlelo lwendandatho ye-indole, okuyi-motif evamile kuma-molecule ahlukahlukene asebenza ngokwebhayoloji.I-3-(N-tosyl-L-alanyloxy) i-indole ivame ukusetshenziswa ekuhlanganiseni kwemithi, amakhemikhali ezolimo, nezinye izinhlanganisela eziphilayo.
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2′-(4-METHYLUMBELLIFERYL)-ALPHA-DN-ACETYLNEURAMINIC ACID SODIUM SALT CAS:76204-02-9
I-2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid usawoti we-sodium iyinhlanganisela yamakhemikhali evame ukusetshenziswa ekuhloleni nasekuhloleni ucwaningo.Iwukuphuma okune-fluorescent okubhalwe ukuthi i-sialic acid, uhlobo lwe-carbohydrate etholakala ebusweni bamaseli.
Le nhlanganisela isetshenziswa njenge-substrate yama-enzyme abizwa ngokuthi ama-neuraminidases, asebenza ukususa izinsalela ze-asilic acid kuma-glycoprotein nama-glycolipids.Uma lawa ma-enzyme enza ku-2′-(4-Methylumbelliferyl)-alpha-DN-acetylneuraminic acid usawoti we-sodium, ukhulula umkhiqizo we-fluorescent owaziwa ngokuthi i-4-methylumbelliferon.
I-fluorescence ekhiqizwa yi-compound ingalinganiswa futhi inqunywe, inikeze ulwazi ngomsebenzi we-neuraminidase enzymes.Lokhu kuwusizo ikakhulukazi ekutadisheni izifo ezihlukahlukene nezimo ezihlobene ne-aberrant sialic acid metabolism.
Inhlanganisela iphinde isetshenziselwe izinjongo zokuxilonga, njengokutholwa kwezifo ezibangelwa amagciwane ezibandakanya umsebenzi we-neuraminidase.Kulezi zivivinyo, inhlanganisela isetshenziselwa ukukhomba ukuba khona kwezinhlobo ezithile zegciwane noma ukuhlola ukusebenza kwe-neuraminidase inhibitors ekwelashweni kwe-antiviral.
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I-CAPS CAS:1135-40-6 Intengo Yomkhiqizi
I-3-Cyclohexylaminopropanesulfonic acid iyinhlanganisela yamakhemikhali eneqembu le-cyclohexyl elixhunywe ku-aminopropanesulfonic acid moiety.Isetshenziswa ngokuyinhloko njenge-ejenti egcina isiphazamiso ezinhlelweni ze-biochemical kanye nemithi.Ngenxa yesakhiwo sayo samakhemikhali esiyingqayizivele, ikhombisa umthamo oqinile wokubhafa futhi ivame ukusetshenziswa ezivivinyweni ezidinga ukulawulwa okunembile kwe-pH, njengokuhlanzwa kwamaprotheni, i-electrophoresis, kanye nokusabela kwe-enzymatic.Ukwengeza, ingasetshenziswa njengesiqinisi ekwakhiweni kwezidakamizwa noma njenge-corrosion inhibitor ezinqubweni ezithile zezimboni.
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I-Alpha-D-Glucose pentaacetate CAS:3891-59-6
I-Alpha-D-glucose pentaacetate iyinhlanganisela yamakhemikhali etholwe nge-acetylating amaqembu e-hydroxyl e-alpha-D-glucose ngamaqembu amahlanu e-acetyl.Ivamise ukusetshenziswa ku-organic synthesis njengeqembu elivikelayo lamaqembu e-hydroxyl akhona kuma-carbohydrates.Ingasetshenziswa futhi njengenhlanganisela yereferensi ocwaningweni lwamakhemikhali nasekuhlaziyeni, nanjengento yokuqala yokuhlanganiswa kwezinhlanganisela ezahlukahlukene.Ukwengeza, i-glucose pentaacetate iphenywe ngokusetshenziswa kwayo okungaba khona ezinhlelweni zokulethwa kwezidakamizwa, ngenxa yezakhiwo zayo ezilawulwayo zokukhululwa.
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I-Tris maleate CAS:72200-76-1
I-Tris maleate iyinhlanganisela yamakhemikhali esebenza njenge-pH buffer kanye nesilungisi ezimbonini ezahlukahlukene.Isetshenziselwa ukugcina amazinga e-pH azinzile kanye nokumelana nezinguquko ezibangelwa ukwengezwa kwama-asidi noma izisekelo.I-Tris maleate ivamise ukusetshenziswa ocwaningweni lwamakhemikhali ezinto eziphilayo, ekuhlanzeni amaprotheni, ezinqubweni zezimboni, nakumakhemikhali okuhlaziya.Isebenza kahle kakhulu kubhafa kububanzi be-pH ephansi futhi idume ngokuguquguquka kwayo ekugcineni izimo ze-pH ezilungile.
