2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridiniuM-9-carboxylate 4′-NHS Ester CAS:194357-64-7

I-2′,6′-DiMethylcarbonylphenyl-10-sulfopropylacridinium-9-carboxylate I-4′-NHS ester iyinhlanganisela yamakhemikhali enesakhiwo sama-molecule esiyinkimbinkimbi. Iqukethe iqembu le-sulfopropylacridinium kanye neqembu elisebenzayo le-carboxylate ester. Ukuba khona kwengxenye ye-ester kubonisa ukuthi iyasabela futhi ingasetshenziswa njenge-ejenti yokulebula noma yokuguqula ama-biomolecule.

Iqembu le-sulfopropylacridinium lale nhlanganisela lisikisela ukuthi lingase libe nokusetshenziswa okungenzeka ekuhlolweni okusekelwe ku-fluorescence, lapho lingasetshenziswa khona njenge-probe noma idayi ye-fluorescent yokuthola nokuhlaziya ama-biomolecule. Lingase futhi libe nokubaluleka ezifundweni zezinqubo zamaseli, njengokubonisana kwe-calcium ngaphakathi kweseli.

Ukufakwa kweqembu le-NHS ester kubonisa ukuthi lingasabela nama-amine ayinhloko, njengalawo atholakala kumaprotheni noma kuma-peptide, ukuze kwakheke ama-amide bond azinzile. Lokhu kusebenza kuyenza ibe usizo ezinhlelweni zokuhlanganisa izinto eziphilayo, lapho ingasetshenziswa khona ukulebula noma ukuguqula ama-biomolecule ngamanye ama-molecule asebenzayo, njenge-fluorophores noma ama-tag.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

Ngokuvamile, ama-compounds aqukethe ama-acridinium derivatives kanye namaqembu e-NHS ester functional angaba nezinhlelo zokusebenza ezahlukahlukene, ikakhulukazi emkhakheni we-bioconjugation kanye ne-fluorescence labeling. Avame ukusetshenziswa ekulebeni ama-biomolecule, njengeprotheni, ama-peptide, nama-nucleic acid, ngamaqembu e-fluorescent noma amanye asebenzayo.

Iqembu le-NHS ester livumela ukusabela kokuxhumanisa okukhethiwe nama-amine ayinhloko, avame ukutholakala kuma-biomolecule. Lokhu kwenza kube lula ukunamathelisa udayi we-fluorescent ku-molecule eqondiwe, okuvumela ukubonakala noma ukutholakala kwezicelo ezahlukahlukene zebhayoloji njenge-fluorescence microscopy, i-flow cytometry, noma i-enzyme-linked immunosorbent assays (ELISA).

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C30H26N2O9S
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe
Inombolo ye-CAS	194357-64-7
Ukupakisha	Encane futhi enkulu
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.