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(S)-2-Amino-4-hydroxybutanoic acid I-CAS:672-15-1
(S) -2-Amino-4-hydroxybutanoic acid iyi-amino acid eyenzeka ngokwemvelo eyaziwa ngokuthi i-L-threonine. Iyisakhiwo esibalulekile samaprotheni futhi inemisebenzi ehlukahlukene emzimbeni. I-L-threonine ibandakanyeka ekwakhiweni kwamaprotheni nasekulungisweni kwezicubu, isekela amasosha omzimba anempilo, inegalelo ekusebenzeni kobuchopho kanye nokwakheka kwe-neurotransmitter, igcina impilo yamathumbu, idlala indima ekukhiqizweni kwe-collagen, futhi isiza ekugayweni kwe-fatty acid. Ibhekwa njenge-amino acid ebalulekile, okusho ukuthi umzimba awukwazi ukuyikhiqiza futhi kumele uyithole ngokudla noma ngokunezela. I-L-threonine inezindlela zokwelapha ezingaba khona ezimweni ezithile zempilo kodwa kufanele isetshenziswe ngaphansi kwesiqondiso sezokwelapha.
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I-2-Ketoglutaric acid disodium salt dihydrate I-CAS:305-72-6
I-2-Ketoglutaric acid I-disodium salt dihydrate iyinhlanganisela yamakhemikhali enefomula i-Na2C5H6O5. Iyifomu likasawoti we-disodium le-2-ketoglutaric acid futhi iqukethe ama-ion amabili e-sodium nama-molecule amabili amanzi nge-molecule ngayinye kasawoti.
I-2-Ketoglutaric acid iyinto ebalulekile emzileni we-metabolic wama-amino acid futhi idlala indima ebalulekile emjikelezweni we-citric acid (owaziwa nangokuthi umjikelezo we-Krebs noma umjikelezo we-TCA) lapho ihlanganyela khona enkambisweni yokukhiqizwa kwamandla.
Uhlobo lwe-disodium salt lwe-2-ketoglutaric acid luthuthukisa ukuncibilika kwayo futhi lwenza kube lula ukuyiphatha nokusebenzisa ezinhlotsheni ezahlukene. Luvame ukusetshenziswa ezifundweni ze-biochemical kanye ne-enzymatic kanye nasekuthuthukisweni nasekukhiqizweni kwemithi kanye namakhemikhali ocwaningo. Luphinde lusetshenziswe ezivivinyweni ezithile zokuxilonga ukuhlola amazinga e-2-ketoglutaric acid kumasampula ebhayoloji.
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I-2-Aminoacetic acid CAS:56-40-6
I-2-Aminoacetic acid, eyaziwa nangokuthi i-glycine noma i-aminoethanoic acid, iyi-amino acid elula kakhulu engabalulekile. Iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali i-NH2CH2COOH. I-Glycine ihlukaniswa njenge-amino acid engathathi hlangothi, e-polar ngenxa yochungechunge lwayo oluseceleni oluqukethe i-athomu ye-hydrogen kuphela. Ngokwesakhiwo iyi-amino acid encane kakhulu futhi ibhekwa njengesakhiwo samaprotheni.
I-Glycine idlala indima ehlukahlukene ezinhlelweni zezinto eziphilayo. Ihilelekile ekwakhiweni kwamaprotheni futhi iyadingeka ekukhiqizweni kwe-collagen, ingxenye enkulu yezicubu ezixhumeneyo. I-Glycine isebenza njenge-neurotransmitter futhi inemiphumela yokuvimbela ohlelweni lwezinzwa oluphakathi, idlala indima ekulawuleni umsebenzi we-neuronal. Iphinde ihileleke ekwakhiweni kwamanye ama-molecule abalulekile njenge-heme, i-purines, ne-glutathione.
Ngaphezu kwalokho, i-glycine isebenza njengesandulela esibalulekile sokwenziwa kwamanye ama-amino acid, njenge-serine ne-creatine. Iyingxenye enkulu yezindlela eziningi zokusabela kwamakhemikhali, okuhlanganisa ukuguqulwa kwe-glucose ibe amandla, kanye nokukhishwa kwe-detox kumakhemikhali esibindini.
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3-(N-tosyl-L-alaninylazy)-5-phenylpyrrole CAS:99740-00-8
3-(I-N-tosyl-L-alaninylazy)-5-phenylpyrrole iyinhlanganisela yamakhemikhali enesakhiwo esiyingqayizivele esihlanganisa iqembu le-tosyl, insalela ye-L-alanine, kanye nengxenye ye-phenylpyrrole.
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3,3′,5,5′-Tetramethylbenzidine sulfate CAS:54827-18-8
I-3,3′,5,5′-Tetramethylbenzidine sulfate iyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-substrate ekuhlolweni kwe-immunosorbent okuxhunywe yi-enzyme (ELISA) nakwezinye izivivinyo ze-biomedical. Ibonisa ukusabela kombala oluhlaza okwesibhakabhaka uma ixutshwe yi-enzyme ethile, okwenza kube wusizo ekuboneni ukuba khona kwama-molecule aqondiwe njenge-antigen nama-antibodies. Le nhlanganisela yaziwa ngokuzwela kwayo okuphezulu kanye nokuqina, okuvumela ukuhlaziywa kwenani okuthembekile nokunembile.
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I-PVP-K30 CAS:9003-39-8 Intengo Yomkhiqizi
I-Polyvinylpyrrolidone (PVP) iyi-polymer yokwenziwa esetshenziswa kabanzi ezimbonini ezahlukahlukene. Iyinhlanganisela encibilikayo emanzini futhi engeyona i-ionic, okwenza ifaneleke ukusetshenziswa njengemithi, izimonyo, izinamathiseli, kanye nokucubungula ukudla. I-PVP yaziwa ngekhono layo lokwakha izinhlanganisela ezizinzile ngezinto eziningi, okwenza ibe yisithako esibalulekile sokwenziwa kwemithi kanye nemikhiqizo yezimonyo. Iphinde ibonise izakhiwo zokwakha amafilimu kanye nezinamathiseli, okwenza ibe usizo ekumbozweni nasekunamathiseleni. Ngaphezu kwalokho, i-PVP ivame ukusetshenziswa njenge-binder kanye ne-stabilizer ekusetshenzisweni kokudla neziphuzo.
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3,4,5,6-Tetrabromophenolsulfonephthalein CAS:77172-72-6
I-3,4,5,6-Tetrabromophenolsulfonephthalein iyinhlanganisela yamakhemikhali yokwenziwa evame ukusetshenziswa njengenkomba ye-pH ekuhlolweni kwelebhu. Ibonakala njenge-okuqinile okuphuzi-nsundu futhi kushintsha umbala kusuka kophuzi kuya koviolet kuye nge-pH ye ikhambi. Le nhlanganisela iwusizo kakhulu ekunqumeni ubumuncu noma i-alkalinity yezinto ezinhlobonhlobo zezicelo zesayensi.
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I-S-Nitrosoglutathione CAS: 57564-91-7 Intengo Yomkhiqizi
S-I-Nitrosoglutathione (GSNO) iyi-molecule encane eyakhiwe ama-amino acid amathathu (i-glutamine, i-cysteine, ne-glycine) kanye neqembu le-nitric oxide (NO). Isebenza njengendawo yokugcina nokuthutha i-nitric oxide, i-molecule ebalulekile yokubonisa emzimbeni. I-GSNO ihilelekile ezinqubweni ezahlukahlukene zomzimba ezifaka phakathi umsebenzi we-antioxidant, ukuguqulwa kwamaprotheni, imiphumela yokulwa nokuvuvukala, kanye nokulawulwa kwenhliziyo nemithambo yegazi. Inezinhlelo zokwelapha ezingaba khona ezimweni ezifana nezifo zenhliziyo, izifo ze-neurodegenerative, kanye nomdlavuza.
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3,5-Dichloro-2-hydroxybenzenesulfonic acid usawoti wesodium CAS:54970-72-8
I-3,5-Dichloro-2-hydroxybenzenesulfonic acid usawoti we-sodium uyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-reagent ekwakhiweni kwezinto eziphilayo. Ibonakala njenge-i-powder ekristalu emhlophe kuya kokumhlophe okungeyona futhi iyancibilika emanzini. Uma kukhona i-chlorine kanye namaqembu e-hydroxyl, ingasetshenziswa ezinhlobonhlobo ze-chemical reactions ezifana ne-sulfonation noma i-halogenation. Le nhlanganisela inezicelo ezimbonini zemithi kanye namakhemikhali njengesisekelo esiphakathi noma esakhiweni sokuhlanganiswa kwamakhemikhali e-organic.
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I-Fluorescein Isothiocyante CAS:3326-32-7
I-Fluorescein isothiocyanate (FITC) iwudayi we-fluorescent ovame ukusetshenziswa ocwaningweni lwezokwelapha kanye nezicelo zokuxilonga. Iwuhlobo lwe-fluorescein olushintshiwe ukuze luqukathe iqembu le-isothiocyanate, elivumela ukuthi libopheke ndawonye kumaprotheni, ama-antibodies, kanye namanye ama-biomolecule.
I-FITC ikhipha ukukhanya okuluhlaza okukhanyayo uma ishukunyiswa ukukhanya kobude be-wavelength obufanele, ngokuvamile obungu-488 nm. Lokhu kukhanya kungatholakala futhi kulinganiswe kusetshenziswa amasu ahlukahlukene okuthwebula izithombe, njenge-fluorescence microscopy, i-flow cytometry, kanye ne-fluorescence spectroscopy.
Ngokuhlanganisa i-FITC nama-biomolecule athakazelisayo, abacwaningi bangalandelela futhi babone ngeso lengqondo ukusatshalaliswa, indawo, kanye nokusebenzisana kwala ma-biomolecule ngaphakathi kwamaseli, izicubu, noma amasampula ezinto eziphilayo. Ama-antibodies anelebula le-FITC, isibonelo, angasetshenziswa ukuthola amaprotheni noma ama-antigen athile ekuhlolweni kwe-immunofluorescence noma ukuhlaziya inani lamaseli ekuhlolweni kwe-flow cytometry.
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I-GSH CAS: 70-18-8 Intengo Yomkhiqizi
I-GSH, noma i-glutathione, iyi-molecule yemvelo ye-antioxidant etholakala emzimbeni. Idlala indima ebalulekile ekugcineni ukusebenza kahle kwamaseli futhi ihilelekile ezinqubweni eziningana ezibalulekile zomzimba. I-GSH isiza ukuvikela amaseli ekulimaleni kwe-oxidative ngokunciphisa ama-free radical ayingozi kanye nezinhlobo ze-oxygen ezisabelayo. Iphinde isize ezinqubweni zokukhipha ubuthi ngokubopha nokususa ubuthi nezinsimbi ezisindayo emzimbeni.
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I-BCA-2Na CAS:979-88-4 Intengo Yomkhiqizi
I-BCA-2Na, eyaziwa nangokuthi i-Bacillus cereus adenosine triphosphate (ATP) bioluminescent assay, iyisivivinyo se-biochemical esisetshenziselwa ukuthola ukuthi kukhona i-ATP kusampula. I-ATP iyi-molecule etholakala kuzo zonke izinto eziphilayo futhi ivame ukusetshenziswa njengesibonakaliso sokungcoliswa noma ukuhlanzeka kwamagciwane. Isivivinyo se-BCA-2Na sisebenzisa i-enzyme luciferase ukuze sivuselele ukusabela okukhiqiza ukukhanya lapho kukhona i-ATP. Ukuqina kokukhanya okukhishwayo kuyalinganiswa futhi kunganikeza ukuhlolwa okusheshayo nokubucayi komsebenzi wamagciwane noma ukuhlanzeka ezimbonini ezahlukahlukene, njengokukhiqizwa kokudla neziphuzo, ukukhiqizwa kwemithi, kanye nokuhlolwa kwekhwalithi yamanzi. Isivivinyo se-BCA-2Na sivame ukusetshenziswa njengendlela esheshayo nethembekile yokuqapha inhlanzeko kanye nokulawula ikhwalithi.
