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I-Methylfolate (L-5 Methyl Calcium Tetrahydrofolate) I-CAS:134-35-0 Umhlinzeki Womkhiqizi
I-5-Methyltetrahydrofolic acid (5-MTHF) iyi-metabolite esebenzayo ye-folate. Idlala indima ebalulekile ekwakhiweni kwe-methionine kusuka ku-homocysteine ngokunikela ngeqembu le-methyl. I-5-Methyltetrahydrofolic acid- (glutamic acid-13C5) iyi-isotope ye-vitamin B9 lapho wonke ama-glutamate carbon amahlanu ethathelwa indawo yi-13C6 carbon.
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I-Creatine phosphate CAS: 67-07-2 Umhlinzeki Womkhiqizi
I-Creatine phosphateiyi-phosphoamino acid equkethe i-creatine eneqembu le-phospho elixhunywe ku-nitrogen eyinhloko yeqembu le-guanidino. Inendima njenge-metabolite yomuntu kanye ne-metabolite yegundane. Iyi-phosphoamino acid kanye ne-phosphagen. Ihlobene ngokusebenza ne-creatine. Iyi-conjugate acid ye-N-phosphocreatinate(2-).
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I-Vitamin A Acid CAS: 302-79-4 Umhlinzeki Womkhiqizi
I-retinoic acid(I-1965)I-Tretinoin）Isetshenziswa kakhulu emithini yesikhumba, okuyisigaba se-vitamin A (Victoria methanol) metabolic intermediates. Ithinta kakhulu ukukhula kwamathambo kanye ne-epithelial metabolism, ingakhuthaza ukwanda kwamaseli e-epithelial kanye nokuvuselelwa, futhi ingavimbela ukwanda kanye nokwehlukaniswa kwama-keratinocytes, ngakho-ke i-hyperkeratosis ingabuyela esimweni sayo esijwayelekile. Ngakho-ke i-keratosis eminingi ephelele noma engaphelele, i-hyperkeratosis yezifo inomphumela othile wokwelapha, yelapha izifo ezahlukahlukene zesikhumba. Ukusetshenziswa komuthi kungangena esikhumbeni esingaphezulu ngokushesha, kuvumele ukwanda okukhulu kwe-epithelial cell turnover. Lolu hlobo lwemithi lunokuvimbela okunamandla nokusheshayo ekukhiqizweni kwezindlala ze-sebaceous, lunganciphisa ukukhiqizwa kwe-sebum. Ngaphezu kwalokho, umkhiqizo ubuye ube nokulwa nomdlavuza, ukhuthaze ukuphulukiswa kwamanxeba kanye nemiphumela yokulwa nokuvuvukala.
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I-L-Carnitine CAS: 541-15-1 Umhlinzeki Womkhiqizi
I-L-Carnitine, eyaziwa nangokuthi i-L-carnitine kanye ne-vitamin BT, ifomula yamakhemikhali yi-C7H15NO3, igama lamakhemikhali yi-(R)-3-carboxyl-2-hydroxy-n, N, n-trimethylammonium propionate hydroxide usawoti wangaphakathi, kanti umuthi omele yi-L-carnitine. Luhlobo lwe-amino acid olukhuthaza ukuguqulwa kwamafutha abe amandla.
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I-Chromium Polynicotinate CAS: 64452-96-6 Umhlinzeki Womkhiqizi
I-Chromium Polynicotinate iyimpuphu ecolekile empunga ebhemayo. Le nto izinzile uma ishisa ekamelweni futhi ayincibiliki emanzini nase-ethanol. Ukusebenza kwe-chromium kungu-3+. Isetshenziswa kakhulu ezithasiselweni zokudla, emikhiqizweni yezempilo yezokwelapha, ezithasiselweni zokudla, njll. Indima yayo ukukhuthaza ukukhula nentuthuko yezilwane, ukusheshisa ukukhiqizwa, nokukhuthaza ukwenziwa kwamaprotheni.
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I-N-Acetyl-D-Glucosamine CAS: 7512-17-6 Umhlinzeki Womkhiqizi
N-I-Acetyl-D-Glucosamine iyi-N-acetyl derivative ye-glucosamine. Ngokwekhemikhali iyi-amide phakathi kwe-glucosamine ne-acetic acid. Ingxenye eyodwa ye-N-acetlyglucosamine exhunywe kuma-serine noma ama-threonine residues kumaprotheni enuzi kanye ne-cytoplasmic -O-GlcNAc, iwukuguqulwa kweprotheyini okutholakala yonke indawo ngemuva kokuguqulwa. Amaprotheni aguquliwe e-O-GlcNAc ahilelekile ekuboneni isimo sezakhamzimba sendawo ezungezile yamaseli nokulungisa umsebenzi wamaprotheni amaseli ngokufanele. I-O-GlcNAc ilawula izimpendulo zamaseli kuma-hormone afana ne-insulin, iqala impendulo yokuvikela ekucindezelekeni, ilawula ikhono leseli lokukhula nokuhlukana, futhi ilawula ukubhalwa kwezakhi zofuzo. Kubantu, ikhona esikhumbeni, e-cartilage nasemithanjeni yegazi njengengxenye ye-hyaluronic acid, kanye nezicubu zamathambo, i-cornea kanye ne-aorta njengengxenye ye-keratan sulfate.
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I-Creatine Pyruvate CAS: 55965-97-4 Umhlinzeki Womkhiqizi
I-Creatine Pyruvate iyinhlanganisela ehlanganisa i-Creatine ne-pyruvic acid futhi isetshenziswa ngabakhi bomzimba njengesengezo ukuze bathole imiphumela ye-ergogenic futhi incibilika ngokuphelele emanzini. Efomini yayo eyinhlanganisela i-Creatine Pyruvate incibilika ngokuphindwe kayishumi kunasefomini yayo ngayinye. Izifundo zemitholampilo zikhombisile ukuthi i-Pyruvate yehlisa amafutha omzimba ngaphandle kokuthinta iphrotheni yemisipha, okuyingxenye ebalulekile ekufezeni isisindo semisipha esiqinile. Izithako ze-Creatine Pyruvate ziwukusekelwa okunempilo okuhle kwabadlali abafuna ukukhulisa ukusebenza kwemisipha nokukhuthazela ezinhlelweni zokuzivocavoca ezinamandla kakhulu.
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I-Vitamin A Palmitat CAS: 79-81-2 Umhlinzeki Womkhiqizi
I-Retinyl palmitate ingeyesigaba samakhemikhali abizwa ngokuthi ama-retinoids, afana ngamakhemikhali ne-vitamin A. Ibonisa umphumela omuhle ekuboneni, esikhumbeni kanye nasekusebenzeni komzimba, ivimbela ukwanda kwamaseli futhi ivimbele umdlavuza. Iyindlela yokudla ebalulekile kanye ne-compound yokwelapha. I-All-trans-retinyl palmitate iyi-all-trans-retinyl ester etholakala ngokufinyela okusemthethweni kweqembu le-carboxy le-palmitic (hexadecanoic acid) neqembu le-hydroxy le-all-trans-retinol. Isetshenziswa emikhiqizweni yezimonyo ukwelapha izifo zesikhumba ezahlukahlukene ezifana ne-acne, ukuguga kwesikhumba, imibimbi, amabala amnyama, futhi ivikela ne-psoriasis. Inendima njenge-metabolite ye-Escherichia coli, i-metabolite ye-xenobiotic yomuntu kanye ne-antioxidant. Iyi-retinyl palmitate kanye ne-all-trans-retinyl ester. Ihlobene ngokusebenza ne-all-trans-retinol.
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I-Benfotiamine CAS: 22457-89-2 Umhlinzeki Womkhiqizi
I-S-Benzoylthiamine I-O-monophosphate (i-Benfotiamine) iyi-derivative ye-S-acyl thiamine etholakala emanzini abandayo. Iyivithamini encibilika kuma-lipid. I-Benfotiamine iqukethe indandatho ye-thiazole. I-Benfotiamine inokutholakala okukhulu kwe-bioavailability kune-thiamine.
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I-Collagen Hydrolyzed CAS: 92113-31-0 Umhlinzeki Womkhiqizi
I-collagen ene-hydrolyzed ibizwa nangokuthi i-collagen ene-hydrolyzed. I-collagen ene-hydrolyzed uhlobo olusha lomkhiqizo we-collagen, olukhiqizwa yi-collagen noma izinsiza ezicebile nge-collagen. Ngaphezu kokwakheka kwe-amino acid okuphawulekayo kwe-collagen (cishe u-30% wezinsalela ze-amino acid iyonke yi-glycine), futhi ine-15-30% yama-amino acid amabili angatholakali kakhulu kwamanye amaprotheni, i-proline kanye ne-4-hydroxyproline Ngaphezu kwe-asidi), iphinde ibe nezici zesisindo esincane sama-molecule, futhi ukwakheka kwakhiwe kakhulu ngama-peptide amancane anesisindo sama-molecule esingaphansi kuka-3000.
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I-Vitamin E Yemvelo CAS: 59-02-9 Umhlinzeki Womkhiqizi
Uwoyela we-Vitamin E uyivithamini encibilika emafutheni, eyaziwa nangokuthi i-tocopherol. Ingenye yama-antioxidants abaluleke kakhulu. Iyizinyibilikisi eziphilayo ezincibilika emafutheni njenge-ethanol, futhi ayincibiliki emanzini, ishisa, iqinile nge-asidi, i-base-labile. Izwela umoya-mpilo kodwa ayincibiliki ekushiseni. Futhi umsebenzi we-vitamin E wawuphansi kakhulu ekuthoseni. I-α-Tocopherol yenziwe kusuka ku-γ-tocopherol ngesenzo se-enzyme i-γ-tocopherol methyltransferase. Iyindlela eyinhloko ye-Vitamin E ku-plasma yomuntu. Ikhona ku-oyela wembewu yelanga.
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I-Curcumin (i-turmeric) 95% I-CAS: 458-37-7 Umhlinzeki Womkhiqizi
I-Curcumin iyi-pigment ephuzi eyinhloko ku-turmeric kanye ne-curry futhi inemisebenzi yokulwa ne-antioxidant, anti-inflammatory, kanye ne-antitumor. Ivimbela ukukhiqizwa kwe-nitric oxide (NO) (IC50 = 6 μM) futhi inciphisa umsebenzi we-nitric oxide synthase (iNOS) ongasebenzi kahle kumaseli e-RAW 264.7 avuselelwe yi-LPS. I-Curcumin ivimbela ukukhishwa kwe-histamine kanye nama-cytokines avuvukalayo i-TNF-α, IL-1β, IL-6, kanye ne-IL-8 avela kumaseli e-HMC-1 mast. Ebuchosheni, i-curcumin yehlisa amazinga e-histamine kanye ne-TNF-α egazini, ivimbela izinguquko ze-histopathological ze-mucosa yamakhala, futhi yehlisa inani lokuthimula kanye nokuhlikihla kwamakhala kumodeli yegundane ye-rhinitis ebangelwa yi-ovalbumin.
