I-N-Acetyl-D-Glucosamine CAS: 7512-17-6 Umhlinzeki Womkhiqizi

N-I-Acetyl-D-Glucosamine iyi-N-acetyl derivative ye-glucosamine. Ngokwekhemikhali iyi-amide phakathi kwe-glucosamine ne-acetic acid. Ingxenye eyodwa ye-N-acetlyglucosamine exhunywe kuma-serine noma ama-threonine residues kumaprotheni enuzi kanye ne-cytoplasmic -O-GlcNAc, iwukuguqulwa kweprotheyini okutholakala yonke indawo ngemuva kokuguqulwa. Amaprotheni aguquliwe e-O-GlcNAc ahilelekile ekuboneni isimo sezakhamzimba sendawo ezungezile yamaseli nokulungisa umsebenzi wamaprotheni amaseli ngokufanele. I-O-GlcNAc ilawula izimpendulo zamaseli kuma-hormone afana ne-insulin, iqala impendulo yokuvikela ekucindezelekeni, ilawula ikhono leseli lokukhula nokuhlukana, futhi ilawula ukubhalwa kwezakhi zofuzo. Kubantu, ikhona esikhumbeni, e-cartilage nasemithanjeni yegazi njengengxenye ye-hyaluronic acid, kanye nezicubu zamathambo, i-cornea kanye ne-aorta njengengxenye ye-keratan sulfate.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

I-N-Acetyl-D-glucosamine isetshenziswa ekuboneni nasekuchazeni i-N-acetyl-beta-D-hexoaminidase. Iphinde isetshenziswe ekwelapheni i-osteoarthritis kanye nesifo samathumbu esivuvukalayo (IBD), okuhlanganisa i-ulcerative colitis kanye nesifo sikaCrohn. Ngaphezu kwalokho, isetshenziswa njengesisekelo ekukhiqizweni kwe-sialic acid, izimonyo kanye nocwaningo lokuthuthukiswa kwemithi. I-N-acetyl-D-Glucosamine (GlcNAc) iyi-monosaccharide derivative ye-glucose. Ikhishwa yisenzo se-O-GlcNAcase, ezinhlelweni zezilwane ezincelisayo ezivela kumaprotheni aguqulwe ngemuva kokuhumusha nge-O-GlcNAc. Amazinga amaprotheni e-O-GlcNAcylation avela ezicutshini zobuchopho zesifo se-Alzheimer ancishisiwe uma kuqhathaniswa nalawo alawulwayo, okuphakamisa ukuthi ukukhululwa kwe-GlcNAc kungasiza ekubangeleni i-pathogenesis.

Isampula Yomkhiqizo

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C8H15NO6
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe kuya kwemhlophe kakhulu
Inombolo ye-CAS	7512-17-6
Ukupakisha	25KG
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.