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I-N-Acetyl-D-Glucosamine CAS: 7512-17-6 Umhlinzeki Womkhiqizi
N-I-Acetyl-D-Glucosamine iyi-N-acetyl derivative ye-glucosamine. Ngokwekhemikhali iyi-amide phakathi kwe-glucosamine ne-acetic acid. Ingxenye eyodwa ye-N-acetlyglucosamine exhunywe kuma-serine noma ama-threonine residues kumaprotheni enuzi kanye ne-cytoplasmic -O-GlcNAc, iwukuguqulwa kweprotheyini okutholakala yonke indawo ngemuva kokuguqulwa. Amaprotheni aguquliwe e-O-GlcNAc ahilelekile ekuboneni isimo sezakhamzimba sendawo ezungezile yamaseli nokulungisa umsebenzi wamaprotheni amaseli ngokufanele. I-O-GlcNAc ilawula izimpendulo zamaseli kuma-hormone afana ne-insulin, iqala impendulo yokuvikela ekucindezelekeni, ilawula ikhono leseli lokukhula nokuhlukana, futhi ilawula ukubhalwa kwezakhi zofuzo. Kubantu, ikhona esikhumbeni, e-cartilage nasemithanjeni yegazi njengengxenye ye-hyaluronic acid, kanye nezicubu zamathambo, i-cornea kanye ne-aorta njengengxenye ye-keratan sulfate.
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I-Creatine Pyruvate CAS: 55965-97-4 Umhlinzeki Womkhiqizi
I-Creatine Pyruvate iyinhlanganisela ehlanganisa i-Creatine ne-pyruvic acid futhi isetshenziswa ngabakhi bomzimba njengesengezo ukuze bathole imiphumela ye-ergogenic futhi incibilika ngokuphelele emanzini. Efomini yayo eyinhlanganisela i-Creatine Pyruvate incibilika ngokuphindwe kayishumi kunasefomini yayo ngayinye. Izifundo zemitholampilo zikhombisile ukuthi i-Pyruvate yehlisa amafutha omzimba ngaphandle kokuthinta iphrotheni yemisipha, okuyingxenye ebalulekile ekufezeni isisindo semisipha esiqinile. Izithako ze-Creatine Pyruvate ziwukusekelwa okunempilo okuhle kwabadlali abafuna ukukhulisa ukusebenza kwemisipha nokukhuthazela ezinhlelweni zokuzivocavoca ezinamandla kakhulu.
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I-Vitamin A Palmitat CAS: 79-81-2 Umhlinzeki Womkhiqizi
I-Retinyl palmitate ingeyesigaba samakhemikhali abizwa ngokuthi ama-retinoids, afana ngamakhemikhali ne-vitamin A. Ibonisa umphumela omuhle ekuboneni, esikhumbeni kanye nasekusebenzeni komzimba, ivimbela ukwanda kwamaseli futhi ivimbele umdlavuza. Iyindlela yokudla ebalulekile kanye ne-compound yokwelapha. I-All-trans-retinyl palmitate iyi-all-trans-retinyl ester etholakala ngokufinyela okusemthethweni kweqembu le-carboxy le-palmitic (hexadecanoic acid) neqembu le-hydroxy le-all-trans-retinol. Isetshenziswa emikhiqizweni yezimonyo ukwelapha izifo zesikhumba ezahlukahlukene ezifana ne-acne, ukuguga kwesikhumba, imibimbi, amabala amnyama, futhi ivikela ne-psoriasis. Inendima njenge-metabolite ye-Escherichia coli, i-metabolite ye-xenobiotic yomuntu kanye ne-antioxidant. Iyi-retinyl palmitate kanye ne-all-trans-retinyl ester. Ihlobene ngokusebenza ne-all-trans-retinol.
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I-Benfotiamine CAS: 22457-89-2 Umhlinzeki Womkhiqizi
I-S-Benzoylthiamine I-O-monophosphate (i-Benfotiamine) iyi-derivative ye-S-acyl thiamine etholakala emanzini abandayo. Iyivithamini encibilika kuma-lipid. I-Benfotiamine iqukethe indandatho ye-thiazole. I-Benfotiamine inokutholakala okukhulu kwe-bioavailability kune-thiamine.
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I-Collagen Hydrolyzed CAS: 92113-31-0 Umhlinzeki Womkhiqizi
I-collagen ene-hydrolyzed ibizwa nangokuthi i-collagen ene-hydrolyzed. I-collagen ene-hydrolyzed uhlobo olusha lomkhiqizo we-collagen, olukhiqizwa yi-collagen noma izinsiza ezicebile nge-collagen. Ngaphezu kokwakheka kwe-amino acid okuphawulekayo kwe-collagen (cishe u-30% wezinsalela ze-amino acid iyonke yi-glycine), futhi ine-15-30% yama-amino acid amabili angatholakali kakhulu kwamanye amaprotheni, i-proline kanye ne-4-hydroxyproline Ngaphezu kwe-asidi), iphinde ibe nezici zesisindo esincane sama-molecule, futhi ukwakheka kwakhiwe kakhulu ngama-peptide amancane anesisindo sama-molecule esingaphansi kuka-3000.
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I-Vitamin E Yemvelo CAS: 59-02-9 Umhlinzeki Womkhiqizi
Uwoyela we-Vitamin E uyivithamini encibilika emafutheni, eyaziwa nangokuthi i-tocopherol. Ingenye yama-antioxidants abaluleke kakhulu. Iyizinyibilikisi eziphilayo ezincibilika emafutheni njenge-ethanol, futhi ayincibiliki emanzini, ishisa, iqinile nge-asidi, i-base-labile. Izwela umoya-mpilo kodwa ayincibiliki ekushiseni. Futhi umsebenzi we-vitamin E wawuphansi kakhulu ekuthoseni. I-α-Tocopherol yenziwe kusuka ku-γ-tocopherol ngesenzo se-enzyme i-γ-tocopherol methyltransferase. Iyindlela eyinhloko ye-Vitamin E ku-plasma yomuntu. Ikhona ku-oyela wembewu yelanga.
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I-Curcumin (i-turmeric) 95% I-CAS: 458-37-7 Umhlinzeki Womkhiqizi
I-Curcumin iyi-pigment ephuzi eyinhloko ku-turmeric kanye ne-curry futhi inemisebenzi yokulwa ne-antioxidant, anti-inflammatory, kanye ne-antitumor. Ivimbela ukukhiqizwa kwe-nitric oxide (NO) (IC50 = 6 μM) futhi inciphisa umsebenzi we-nitric oxide synthase (iNOS) ongasebenzi kahle kumaseli e-RAW 264.7 avuselelwe yi-LPS. I-Curcumin ivimbela ukukhishwa kwe-histamine kanye nama-cytokines avuvukalayo i-TNF-α, IL-1β, IL-6, kanye ne-IL-8 avela kumaseli e-HMC-1 mast. Ebuchosheni, i-curcumin yehlisa amazinga e-histamine kanye ne-TNF-α egazini, ivimbela izinguquko ze-histopathological ze-mucosa yamakhala, futhi yehlisa inani lokuthimula kanye nokuhlikihla kwamakhala kumodeli yegundane ye-rhinitis ebangelwa yi-ovalbumin.
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I-Vitamin B1 (i-Thiamine Hydrochloride) I-CAS: 67-03-8 Umhlinzeki Womkhiqizi
I-Thiamine Hydrochloride uhlobo lukasawoti lwe-thiamine (i-vitamin B1), i-vitamin ebalulekile ekusebenzeni kwe-aerobic, ukukhula kwamaseli, ukudluliselwa kwemizwa yezinzwa kanye nokwakheka kwe-acetylcholine. I-Vitamin B1 isiza ukuvimbela izinkinga ezahlukahlukene zempilo okuhlanganisa nokulimala kwenhliziyo.
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Umhlinzeki Womkhiqizi we-Hydroxycobalamin HCL CAS:78091-12-0
I-Hydroxycobalamin (ohcbl, noma i-B12a) uhlobo lwemvelo lwe-vitamin B12, noma olunye lwezinhlobo ze-vitamin B12. Ilungu eliyisisekelo leqembu le-cobalamine. Amabhaktheriya amaningi akhiqiza amavithamini akhiqiza i-vitamin B12 ngendlela ye-hydroxycobalamin. I-Hydroxycobalamin ibomvu ngokumnyama. I-Vitamin B12 emzimbeni womuntu ayivamile ukuba khona ngendlela ye-hydroxycobalamin. Kodwa-ke, kubantu, i-hydroxycobalamin iguqulwa kalula ibe uhlobo lwe-coenzyme oluwusizo lwe-vitamin B12. Umkhiqizo we-hydroxycobalamin wezokwelapha uwumjovo wawo ongenamagciwane, osetshenziselwa ukwelapha ukuntuleka kwamavithamini kanye nobuthi be-cyanide (ngoba uyahambisana nama-ion e-cyanide).
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I-Collagen II CAS: 9064-67-9 Umhlinzeki Womkhiqizi
I-Collagen iyona eyinhloko ye-extracellular matrix enamaprotheni amaningi esakhiwo se-fibrous kuzo zonke izingxenye eziphakeme. Itholakala kakhulu ezicutshini ze-fibrous ezifana nesikhumba, i-ligament kanye ne-tendon ngesimo se-fibrils ende futhi itholakala kakhulu ku-cornea, imithambo yegazi, amathambo, i-cartilage, i-intervertebral disc kanye namathumbu. Lawa amaprotheni amaningi kakhulu ezincelisayo akha ngaphezu kwama-30% amaprotheni aphelele emzimbeni wesilwane.
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I-Nicotinamide Riboside (Chloride) CAS:23111-00-4 Umhlinzeki Womkhiqizi
I-Nicotinamide Riboside Chloride uhlobo lukasawoti we-chloride lwe-nicotinamide riboside (NR). I-NR uhlobo olusha lwe-pyridine-nucleoside ye-vitamin B3 olusebenza njengesandulela se-nicotinamide adenine dinucleotide (NAD) noma i-NAD+. I-Nicotinamide riboside chloride uhlobo lwekristalu lwe-Nicotinamide riboside (NR) chloride. I-Nicotinamide riboside chloride inyusa amazinga e-NAD[+] futhi isebenze i-SIRT1 ne-SIRT3, okuholela ekuthuthukisweni kwe-oxidative metabolism kanye nokuvikelwa ekuphazamisekeni kwe-metabolic okubangelwa ukudla okunamafutha amaningi. I-Nicotinamide riboside chloride isetshenziswa ezithasiselweni zokudla.
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I-D-Fructose 1,6-Disphosphate Trisodium Salt CAS:38099-82-0
I-Fructose-1,6-biphosphate (F1,6P) iyi-glycolytic intermediate ekhiqizwa ukudluliselwa kwe-phosphate kusuka ku-ATP iye ku-fructose-6-phosphate yi-enzyme i-phosphofructokinase. I-Fructose-1,6-biphosphate, kanye ne-fructose-2,6-biphosphate, ilawula umsebenzi we-phosphofructokinase-1 (PFK-1), isinyathelo esinciphisa izinga ku-glycolysis. Ngesikhathi se-glycolysis, i-aldolase ihlukanisa i-Fructose-1,6-biphosphate ibe yi-dihydroxacetone phosphate (DHAP) kanye ne-glyceraldehyde phosphate. I-Fructose-1,6-biphosphate iphinde ibe yi-allosteric activator ye-M2 isoform ye-Pyruvate Kinase (PK-M2), uhlobo oluyinhloko lwe-pyruvate kinase kumaseli omdlavuza.
