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I-TOOS CAS: 82692-93-1 Intengo Yomkhiqizi
I-Sodium 3-(N-ethyl-3-methylanilino)-2-hydroxypropanesulfonate iyinhlanganisela yamakhemikhali eyaziwa kakhulu ngokuthi i-MESNa. Isetshenziswa ngokuyinhloko njenge-ejenti yokunciphisa ku-biochemistry kanye ne-molecular biology. I-MESNa inamandla okuphula izibopho ze-disulfide kumaprotheni, iwaguqule abe amaqembu e-sulfhydryl. Le nqubo yokunciphisa ibalulekile ekusetshenzisweni okuhlukahlukene njengokuguqulwa kwamaprotheni, ukuvimbela ukuhlanganiswa kwamaprotheni, ukulebula amaprotheni, kanye nokugoqwa kabusha kwamaprotheni. I-MESNa idlala indima ebalulekile ekuphathweni kwamaprotheni, ekuhlaziyweni nasekuguqulweni kocwaningo lwesayensi.
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I-CAPSO Na CAS:102601-34-3 Intengo Yomkhiqizi
I-CAPSO Na, eyaziwa nangokuthi i-3-(cyclohexylamino)-2-hydroxy-1-propanesulfonic acid sodium salt, iyinhlanganisela eyingxenye yomndeni wama-sulfonic acid. Iyi-zwitterionic buffer evame ukusetshenziswa ezinhlotsheni ezahlukene ze-biochemical kanye ne-molecular biology.
I-CAPSO Na isebenza njenge-ejenti elawula i-pH esebenzayo futhi isetshenziswa kabanzi ekwakhiweni kwe-buffer ukugcina i-pH ezinzile ebangeni elithile. Inenani le-pKa elicishe libe ngu-9.8 futhi ivame ukusetshenziswa ezivivinyweni ezidinga i-pH ephakathi kuka-8.5 no-10.
Uhlobo lwe-sodium salt lwe-CAPSO (CAPSO Na) luthuthukisa ukuncibilika kanye nokulula kokuphathwa uma kuqhathaniswa nohlobo lwe-free acid. Luncibilika emanzini futhi lwakha kalula izixazululo ezizinzile ngamanani ahlukene, okwenza kube lula ukusetshenziswa kwelebhu ehlukahlukene.
Ezinye izindlela ezivamile zokusebenzisa i-CAPSO Na zifaka phakathi ukusebenza njenge-buffer kumasu e-electrophoresis, ukuhlolwa kwama-enzyme, ukuhlanzwa kwamaprotheni, kanye nemidiya yokukhulisa amaseli. Amandla ayo okugcina nokuhambisana nezinhlelo zezinto eziphilayo kunegalelo ekusebenzeni kwayo kulezi zinsimu.
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2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0
I-2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl I-2,2,2-trichloreacetimidate iyinhlanganisela yamakhemikhali evame ukusetshenziswa kumakhemikhali e-carbohydrate kanye nokusabela kwe-glycosylation. Ivela ku-α-D-galactopyranose, uhlobo lukashukela, lapho amaqembu e-hydroxyl ezindaweni ezingu-2, 3, 4, kanye no-6 zendandatho ye-galactopyranose e-acetylated. Ngaphezu kwalokho, i-anomeric carbon (C1) kashukela ivikelwe yiqembu le-trichloroacetimidate, elenza libe yi-electrophile enamandla ngesikhathi sokusabela kwe-glycosylation.
Le nhlanganisela ivame ukusetshenziswa njenge-ejenti ye-glycosylating ukwethula izingxenye ze-galactose kuma-molecule ahlukahlukene, njengeprotheni, ama-peptide, noma ama-molecule amancane e-organic. Lokhu kungafezwa ngokuphendula le nhlanganisela nge-nucleophile (isb., amaqembu e-hydroxyl ku-molecule eqondiwe) ngaphansi kwezimo ezifanele. Iqembu le-trichloroacetimidate lenza kube lula ukunamatheliswa kwengxenye ye-galactose ku-molecule eqondiwe, okuholela ekwakhekeni kwesibopho se-glycosidic.
Le nhlanganisela ivame ukusetshenziswa ekwakhiweni kwama-glycoconjugates, ama-glycopeptides, nama-glycolipids. Inikeza indlela eguquguqukayo nephumelelayo yokuguqula ama-molecule anezinsalela ze-galactose, ezingaba usizo emikhakheni ehlukahlukene, kufaka phakathi izifundo zezinto eziphilayo, izinhlelo zokulethwa kwemithi, noma ukuthuthukiswa kwemithi yokugoma.
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I-AMPD CAS: 115-69-5 Intengo Yomkhiqizi
I-2-Amino-2-methyl-1,3-propanediol, eyaziwa nangokuthi i-AMPD noma i-α-methyl serinol, iyinhlanganisela yamakhemikhali enefomula yama-molecule i-C4H11NO2. Iyi-amino alcohol evame ukusetshenziswa njenge-intermediate yamakhemikhali ekwakhiweni kwemithi kanye namakhemikhali e-organic. I-AMPD yaziwa ngekhono layo lokusebenza njenge-chiral assistant ekuphenduleni okungalingani, okwenza ibe wusizo ekukhiqizweni kwamakhemikhali ahlanzekile e-enantiomerically. Ngaphezu kwalokho, isetshenziswe njengesithako ekunakekelweni komuntu siqu kanye nemikhiqizo yezimonyo ngenxa yezakhiwo zayo zokuthambisa.
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Usawoti we-MES sodium CAS: 71119-23-8
Usawoti we-MES sodium, owaziwa nangokuthi usawoti we-sodium we-2-(N-morpholino)ethanesulfonic acid, uyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-ejenti yokubopha. Iyi-asidi enenani le-pKa elingaba ngu-6.15. Usawoti we-MES sodium uncibilika kakhulu emanzini futhi ububanzi bawo bokubopha obusebenzayo bungama-pH angu-5.5 kuya ku-6.7. Usetshenziswa kabanzi ocwaningweni lwe-biochemical kanye ne-biological, kanye nasekuphenduleni kwamakhemikhali ahlukahlukene, ukuhlanzwa kwamaprotheni, i-gel electrophoresis, izifundo ze-enzyme, kanye nokuhlolwa kokukhuliswa kwamaseli. Ifomu likasawoti we-sodium lithuthukisa ukuncibilika kanye nokuqina kwenhlanganisela, okwenza kube lula ukuyiphatha nokusebenzisa ezindaweni zelebhu.
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i-beta-d-glucose pentaacetate CAS:604-69-3
I-Beta-D-glucose pentaacetate iyinhlanganisela yamakhemikhali etholakala ku-glucose, ushukela olula. Yakhiwa yi-acetylating glucose enamaqembu amahlanu e-acetyl, okuholela ekunamatheleni kwala maqembu kumaqembu e-hydroxyl (OH) akhona ku-molecule ye-glucose. Lokhu kuguqulwa kwe-glucose kuyinika ukuzinza okuthuthukisiwe futhi kuyenze incibilike ezinyibilikisweni eziphilayo.
I-Beta-D-glucose pentaacetate inezinhlelo zokusebenza ezahlukahlukene emkhakheni we-organic chemistry, ikakhulukazi ekuhlanganisweni nasekuguqulweni kwama-carbohydrate. Ingasebenza njengesandulela noma isikhombisi-ndlela ekulungiseleleni ezinye izinto ezisuselwa kuma-carbohydrate noma amakhemikhali e-organic ayinkimbinkimbi. Ngaphezu kwalokho, isetshenziswe kwezinye izinhlelo zezokwelapha nezemithi ezifana nezinhlelo zokulethwa kwemithi kanye nezindlela zokukhishwa ezilawulwayo.
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I-2-(tris(hydroxymethyl)methylamino)ethane-1-sulphonic acid I-CAS:7365-44-8
I-2-(Tris(hydroxymethyl)methylamino)ethane-1-sulfonic acid, efushaniswe ngokuthi i-TES, iyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-ejenti yokubopha ocwaningweni lwezinto eziphilayo kanye namakhemikhali. Njenge-sulfonic acid derivative ye-tris(hydroxymethyl)aminomethane (Tris), i-TES ingagcina ububanzi be-pH obuzinzile obungu-6.8 kuya ku-8.2. Ivame ukusetshenziswa kwimidiya yokukhulisa amaseli, ukusabela kwe-enzyme, i-protein electrophoresis, kanye nocwaningo lwe-DNA/RNA. I-TES iguquguquka kakhulu futhi ibalulekile ekugcineni izimo ezifanele ekuhlolweni nasemasuni ahlukahlukene elebhu.
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i-piperazine-1,4-bis(2-ethanesulfonic acid) usawoti we-disodium CAS:76836-02-7
I-Disodium piperazine-1,4-diethanesulphonate iyinhlanganisela yamakhemikhali evame ukusetshenziswa njenge-ejenti yokubopha kanye ne-stabilizer ezinhlotsheni ezahlukene zesayensi nezokwelapha. Usawoti we-sodium ongokwemvelo otholakala ku-piperazine kanye ne-diethanesulphonic acid.
Le nhlanganisela incibilika kakhulu emanzini futhi inokubukeka okumhlophe okukristalu. Yaziwa ngezakhiwo zayo zokulawula i-pH, okusiza ukugcina i-acidity noma i-alkalinity yezixazululo ngaphakathi kobubanzi obufunwayo.
Ukusetshenziswa okukhulu kwe-disodium piperazine-1,4-diethanesulphonate kusemkhakheni we-electrophysiology kanye ne-neurobiology. Ivame ukusetshenziswa njengengxenye yezixazululo zokuqopha ze-electrophysiological kanye nemidiya yokukhulisa amaseli ukuze kulondolozwe ukuzinza nobuqotho bamaseli nezicubu ngesikhathi sezinqubo zokuhlola.
Ngaphezu kwalokho, le nhlanganisela itholakale inemiphumela ethile yokuvikela izinzwa kanye ne-antioxidant, okwenza ibe usizo ocwaningweni oluhlobene nesistimu yezinzwa ephakathi kanye nokucindezeleka kwe-oxidative.
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2-NAPHTHYL-BETA-D-GALACTOPYRANOSIDE CAS:312693-81-5
I-2-NAPHTHYL-BETA-D-GALACTOPYRANOSIDE iyinhlanganisela yamakhemikhali evame ukusetshenziswa ocwaningweni nasekuhlaziyweni kwamakhemikhali. Ivela ku-galactose, uhlobo lukashukela. Le nhlanganisela ivame ukusetshenziswa njengesisekelo sokuthola umsebenzi we-beta-galactosidase, i-enzyme ekhona ezintweni eziningi eziphilayo, kufaka phakathi amabhaktheriya. Lapho i-beta-galactosidase ikhona, ihlukanisa i-2-NAPHTHYL-BETA-D-GALACTOPYRANOSIDE ibe yi-naphthol kanye ne-galactose. I-molecule ye-naphthol etholakala ingatholakala kalula ngokumunca kwayo ukukhanya kwe-ultraviolet, okuvumela ososayensi ukuthi balinganise umsebenzi we-beta-galactosidase. Lokhu kuhlolwa kuvame ukusetshenziswa ocwaningweni lwe-molecular biology kanye nezakhi zofuzo, njengezicelo ezinjengokufunda ukulawulwa kwezakhi zofuzo, ukuvezwa kwamaprotheni, kanye nokuphila kwamaseli.
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I-TOPS CAS:40567-80-4 Intengo Yomkhiqizi
I-Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate iyinhlanganisela yamakhemikhali enesakhiwo esiyinkimbinkimbi sama-molecule. Ivame ukusetshenziswa ezinhlotsheni ezahlukene zesayensi nocwaningo. Le nhlanganisela iyi-sulfonate derivative, eyaziwa ngokuncibilika kwayo emanzini nakwezinye izinyibilikisi ze-polar. Ingasetshenziswa njenge-reagent noma i-additive ekusabeleni nasekucubungulweni kwamakhemikhali. Ngenxa yesakhiwo sayo esiyingqayizivele kanye nezakhiwo zayo, i-Sodium 3-(N-ethyl-3-methylanilino)propanesulfonate ivame ukusetshenziswa ekuthuthukisweni kwemithi, udayi, kanye nezinye izinhlanganisela eziphilayo.
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I-CHES Na CAS:103-47-9 Intengo Yomkhiqizi
I-2-(Cyclohexylamino)ethanesulfonic acid iyinhlanganisela yamakhemikhali enefomula yama-molecule C10H21NO3S. Yaziwa nangokuthi isifinyezo sayo i-CHES. I-CHES iyi-derivative ye-sulfonic acid equkethe kokubili iqembu lama-amino kanye neqembu le-sulfonic acid esakhiweni sayo.
I-CHES ivame ukusetshenziswa njenge-ejenti yokuvimba ocwaningweni lwe-biochemical kanye ne-biological. Izinzile nge-pH futhi igcina indawo ye-pH ehambisanayo, ikakhulukazi ezindaweni zelebhu ezibandakanya ukusabela kwe-enzyme noma izifundo zamaprotheni. I-CHES ine-pKa engu-9.3, okwenza ibe yi-buffer ephumelelayo ezungeze i-pH engu-9.
Isakhiwo sayo samakhemikhali esiyingqayizivele kanye nezakhiwo zayo kwenza i-CHES ibe usizo ezinhlelweni ezahlukahlukene, njengokulungiselela izixazululo ze-buffer ze-electrophoresis, ukuhlolwa kwe-enzyme, kanye nemidiya yokukhulisa amaseli. Ngokuvamile ikhethwa ezinhlelweni ezidinga ububanzi be-pH obungu-8.5 kuya ku-10.
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2,3,4,6-Tetra-O-benzyl-D-galactopyranose CAS:53081-25-7
I-2,3,4,6-Tetra-O-benzyl-D-galactopyranose iyinhlanganisela evame ukusetshenziswa ekwakhiweni kwezinto eziphilayo, ikakhulukazi emkhakheni we-carbohydrate chemistry. Isebenza njengeqembu elivikela amaqembu e-hydroxyl e-galactose, okuvimbela ukusabela okungafuneki ngesikhathi sokuguqulwa kwamakhemikhali. Le nhlanganisela yakhiwa yi-molecule ye-galactose enamaqembu amane e-benzyl anamathele kumaqembu e-hydroxyl ezindaweni 2, 3, 4, kanye no-6 zendandatho ye-galactose.
Ukuba khona kwamaqembu e-benzyl kuvikela amaqembu e-hydroxyl, okwenza angasebenzi, kuyilapho kulondolozwa ukusabela kwamanye amaqembu asebenzayo ku-molecule. Lokhu kwenza ukuguqulwa okukhethiwe kwe-galactose noma ukuguqulwa okuqhubekayo kwenzeke ngaphandle kokuthinta amaqembu e-hydroxyl avikelwe.
I-2,3,4,6-Tetra-O-benzyl-D-galactopyranose ivame ukusetshenziswa njengento yokuqala yokwenziwa kwama-carbohydrate ayinkimbinkimbi, ama-glycoconjugates, noma amanye ama-compounds aqukethe izinsalela ze-galactose. Iwusizo kakhulu ekuphenduleni kwe-glycosylation, lapho isebenza njengomnikeli we-glycosyl ophumelelayo, okwenza kube lula ukunamathela kwe-galactose kuma-molecule amukelayo.
