I-Simvastatin CAS:79902-63-9 Umkhiqizi Womhlinzeki

I-Simvastatin i-semi-synthetic, i-hydrophobic kancane, i-analogue ye-lovastatin.Njenge-lovastatin, i-simvastatin iyi-inhibitor ethile ye-HMG-CoA reductase futhi isetshenziswa ngokwelapha ukwehlisa i-cholesterol ye-LDL.Muva nje, ama-statins abe uphenyo olubalulekile lwe-biochemical ku-cell biology.Ukuzibandakanya kwabo ezenzakalweni eziningi kungahlotshaniswa nendlela yabo yokusebenza eyinhloko, nokho, indlela yokusebenza yeminye imiphumela eminingi ibonakala kancane. I-Simvastatin iyi-inhibitor ethile ye-HMG-CoA reductase, i-enzyme edala ukuguqulwa kwe-HMG-CoA. i-mevalonate, isinyathelo sokuqala se-cholesterol biosynthesis.Isetshenziswa ekwelapheni i-hypercholesterolemia, njengoba inciphisa amazinga e-low density lipoproteins kanye ne-triglycerides, futhi ikhuphule amazinga e-high-density lipoprotein.