I-Setmelanotide CAS:920014-72-8 Umhlinzeki Womkhiqizi

I-Setmelanotide iyi-agonist ye-melanocortin-4 receptor (MC4R). Ukusetshenziswa kwayo kufaka phakathi ukwelashwa kwezifo ezithile zofuzo ezihlobene nokukhuluphala, njengokuntuleka kwe-pro-opiomelanocortin (POMC), ukuntuleka kwe-leptin receptor (LEPR), kanye ne-Bardet-Biedl syndrome. I-Setmelanotide isetshenziselwa ukuphatha ukukhuluphala okukhulu ezigulini ezinalezi zimo ezithile zofuzo, ngokusiza ekulawuleni isifiso sokudla kanye nesisindo somzimba. Imiphumela emibi evame kakhulu ihlanganisa ukusabela kwendawo yomjovo, i-hyperpigmentation yesikhumba (amabala esikhumba amnyama kunesikhumba esizungezile), ikhanda elibuhlungu kanye nemiphumela emibi yesisu (njengesicanucanu, uhudo, kanye nobuhlungu besisu), phakathi kwezinye. Ukuma kobulili okuzenzakalelayo kwabesilisa kanye nokusabela okubi kocansi kwabesifazane kuye kwenzeka ngokwelashwa. Ukucindezeleka kanye nemicabango yokuzibulala nakho kuye kwenzeka nge-setmelanotide.