Umhlinzeki Womkhiqizi we-Rosuvastatin Calcium CAS:147098-20-2

I-Rosuvastatin calcium iyisithibi esikhethiwe se-HMG-CoA reductase. Isithibi se-HMG-CoA reductase yi-enzyme enciphisa izinga le-transition hydroxy-3-methylglutaryl coenzyme A ukuze i-valerate A (I-precursor ye-cholesterol). Indawo eyinhloko yesenzo se-rosuvastatin yisibindi - izitho eziqondiwe zokwehlisa i-cholesterol. I-Rosuvastatin yandisa inani lama-receptor e-hepatic LDL ebusweni beseli, ikhuthaza ukumuncwa kanye ne-catabolism ye-LDL, ivimbela ukwakheka kwe-VLDL kwesibindi, ngaleyo ndlela inciphise inani eliphelele lezinhlayiya ze-VLDL kanye ne-LDL. I-Rosuvastatin calcium iyakwazi ukuvimbela i-reductase yesibindi ye-methylglutaryl coenzyme A, futhi iqhubeka nomphumela wayo omuhle ekunciphiseni amafutha. Inesikhathi eside sokuphila. Ubulili kanye nobudala beziguli abunawo umthelela omkhulu ekusetshenzisweni kwemithi.