I-3-Morpholino-2-hydroxypropanesulfonic acid usawoti we-sodium, owaziwa nangokuthi usawoti we-sodium we-MES, iyinhlanganisela yamakhemikhali evamise ukusetshenziswa njenge-ejenti ephazamisayo ocwaningweni lwebhayoloji nolwe-biochemical.
I-MES iyibhafa ye-zwitterionic esebenza njengesilawuli se-pH, egcina i-pH izinzile ezinhlelweni ezihlukene zokuhlola.Incibilika kakhulu emanzini futhi inenani le-pKa elilinganiselwa ku-6.15, okuyenza ifaneleke ukugcinwa kumthamo kububanzi be-pH obungu-5.5 ukuya ku-7.1.
Usawoti we-sodium we-MES uvame ukusetshenziswa kumasu ebhayoloji yamangqamuzana afana nokuhlukaniswa kwe-DNA ne-RNA, ukuhlolwa kwama-enzyme, nokuhlanzwa kwamaprotheni.Iphinde isetshenziswe emithonjeni yemidiya yamaseli ukuze kugcinwe indawo ezinzile ye-pH yokukhula kwamaseli nokwanda.
Isici esisodwa esiphawulekayo se-MES ukuzinza kwayo ngaphansi kwezimo ze-physiological kanye nokumelana nokushintsha kwezinga lokushisa.Lokhu kuyenza ifanelekele ukusetshenziswa ekuhloleni lapho kulindeleke khona ukuguquka kwezinga lokushisa.
Abacwaningi bavame ukukhetha usawoti we-sodium we-MES njengesivimbeli ngenxa yokuphazanyiswa okuncane kokusabela kwe-enzymatic kanye nomthamo we-buffer ephezulu ngaphakathi kwebanga le-pH elifanele.