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I-Cyclopentyl isocyanate CAS:4747-71-1
I-Cyclopentyl isocyanate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule C6H11NO. Iqukethe indandatho ye-cyclopentane eneqembu elisebenzayo le-isocyanate (–N=C=O) elinikeza ukusabela okuphawulekayo. Lolu ketshezi olungenambala kuya kophuzi olukhanyayo lusetshenziswa kakhulu ekwakhiweni kwezinto ezahlukahlukene zamakhemikhali, okuhlanganisa nemithi kanye namakhemikhali ezolimo. Amandla alo okuhlanganyela ekwelashweni kokwengeza kwe-nucleophilic avumela ukusebenza kwamanye amakhemikhali ezinto eziphilayo, okwenza kube yindawo ebalulekile ekwakhiweni kwezinto eziphilayo kanye ne-polymer chemistry.
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1,5-Pentanediol CAS:111-29-5
I-1,5-Pentanediol iyinhlanganisela yezinto eziphilayo echazwa yifomula i-C5H12O2. Ingeyomndeni wama-diol, enamaqembu amabili e-hydroxyl (–OH) ezindaweni zokuqala nezesihlanu zekhabhoni esakhiweni se-carbon straight-chain emihlanu. Lolu ketshezi olungenambala, oluyi-hygroscopic luyancibilika emanzini kanye nezinhlobo ezahlukene zezinyibilikisi zezinto eziphilayo. I-1,5-Pentanediol isetshenziswa kakhulu ekuhlanganiseni ama-polyester nama-polyurethane, okwenza ibe yigugu ezinhlotsheni ezahlukene zezimboni. Ngaphezu kwalokho, isebenza njengesinyibilikisi, i-plasticizer, kanye ne-ejenti yokugcina umswakama ezimonyweni nasezikhiqizweni zokunakekelwa komuntu siqu, okunegalelo ekubalulekeni kwayo okukhula embonini yamakhemikhali.
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I-5-Bromopentan-1-ol CAS:34626-51-2
5-I-Bromopentan-1-ol iyinhlanganisela yezinto eziphilayo enefomula yama-molecule C5H11BrO. Iqukethe i-athomu ye-bromine enamathiselwe ku-carbon yesihlanu yochungechunge lwe-pentanol, okwenza kube yinto ewusizo etholakala kuma-alcohols aqondile. Le nhlanganisela ibonakala njengoketshezi olungenambala kuya kophuzi olukhanyayo futhi isetshenziswa kakhulu ekuhlanganisweni kwezinto eziphilayo. Isebenza njenge-reagent ekuphenduleni okuhlukahlukene kwamakhemikhali, ikakhulukazi ekuguqulweni okubandakanya ukusabela kwe-halogenation kanye nokufakwa esikhundleni kwe-nucleophilic. I-5-Bromopentan-1-ol ibalulekile ekwakhiweni kwamakhemikhali ahlukahlukene, okuhlanganisa nemithi, amakhemikhali ezolimo, nezinye izinto eziphilayo ezisebenzayo.
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4-tert-Butylcyclohexyl chloroformate CAS:42125-46-2
4-I-tert-Butylcyclohexyl chloroformate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule C12H19ClO2. Iqukethe iqembu elisebenzayo le-chloroformate elinamathiselwe endandatho ye-cyclohexane ehlotshiswe ngeqembu le-tert-butyl endaweni engu-4. Lolu ketshezi oluphuzi olungenambala kuya koluphuzi lusetshenziswa kakhulu njengeqembu elivikelayo ekwakhiweni kwezinto eziphilayo, ikakhulukazi ekusebenzeni kwama-alcohols nama-amine. Ukusebenza kwalo kuvumela ukuthi linikeze ingxenye ye-chloroformate, engasetshenziswa ngempumelelo ekuphenduleni kwe-acylation, okwenza kube yi-reagent ebalulekile kumakhemikhali ezokwelapha kanye nokuhlanganiswa kwama-molecule ayinkimbinkimbi ezinto eziphilayo.
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I-4-Methoxyphenacyl chloride CAS:2196-99-8
4-I-Methoxyphenacyl chloride iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C10H9ClO2. Ineqembu le-phenacyl elithathelwe indawo yiqembu le-methoxy endaweni ye-para, okuholela ekuphumeni koketshezi oluphuzi olungenambala. Le nhlanganisela isetshenziswa kakhulu njenge-reagent ekwakhiweni kwezinto eziphilayo, ikakhulukazi ekwakhiweni kwamaqembu okuvikela asuswayo kanye nasekuhlanganisweni kwamakhemikhali asebenzayo ngokwezinto eziphilayo. Amandla ayo okusabela nama-nucleophiles ayenza ibe yindawo ebalulekile emikhondweni eyahlukene yokwenziwa, okuhlanganisa ukusetshenziswa kwe-chemistry yezokwelapha kanye nesayensi yezinto zokwakha.
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I-2-CHLOROBENZYL CHLOROFORMATE CAS:39545-31-8
2-I-chlorobenzyl chloroformate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C9H8Cl2O2. Njengoba ineqembu le-chloroformate elixhunywe engxenyeni ye-2-chlorobenzyl, lolu ketshezi olungenambala kuya kophuzi olukhanyayo lusetshenziswa kakhulu njenge-reagent ekwakhiweni kwezinto eziphilayo. Isebenza njengeqembu elivikela ama-alcohols nama-amine, okuvumela ukuthi lezi zenzo zifihlwe ngokukhetha ngesikhathi sokusabela okuyinkimbinkimbi kwezinyathelo eziningi. Ukusebenza kwayo kusiza ukwakheka kwama-carbamates nama-ester, okwenza kube yindawo ebalulekile ekwakhiweni kwemithi kanye nezinye izinto ezibalulekile zamakhemikhali.
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I-Trichloroethanol CAS:115-20-8
I-Trichloroethanol, eyaziwa nangokuthi i-2,2,2-trichloroethanol, iwuketshezi olungenambala, oluqinile olunefomula yamakhemikhali ye-C2HCl3O. Itholakala ekufakweni kwe-ethanol nge-chlorine futhi ivame ukusetshenziswa njengesinyibilikisi futhi iphakathi kokwenziwa kwezinto eziphilayo. I-Trichloroethanol inephunga elimnandi futhi incibilika kancane emanzini. Ngokuyinhloko, isebenza njengesandulela samakhemikhali ahlukahlukene kanye nemithi. Amandla ayo okusebenza njengesidambisi-zinhlungu futhi iyenza ifaneleke emkhakheni wezokwelapha, ikakhulukazi ekwakhiweni kwemithi ethile. Kodwa-ke, izinyathelo zokuphepha ziyadingeka ngenxa yobuthi bayo obungaba khona kanye nomthelela emvelweni.
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4-Methylcyclohexanol CAS:589-91-3
4-I-Methylcyclohexanol iyinhlanganisela yezinto eziphilayo enefomula yama-molecule i-C7H14O. Inendandatho ye-cyclohexane eneqembu le-methyl kanye neqembu le-hydroxyl (–OH) endaweni yesine. Lolu ketshezi olungenambala, olunamafutha luvame ukusetshenziswa njengesinyibilikisi ngenxa yezakhiwo zalo ezinhle zamakhemikhali. Inephunga elincane kanye nokuguquguquka okuphansi, okwenza ifaneleke ukusetshenziswa okuhlukahlukene embonini yamakhemikhali. I-4-Methylcyclohexanol isetshenziswa kakhulu ekukhiqizweni kwamanye amakhemikhali futhi njenge-intermediate ekwakhiweni, ifaka isandla ekwenziweni kwama-plasticizer, ama-resins, nama-surfactants.
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4-Chloroanisole CAS: 623-12-1
4-I-Chloroanisole, inhlanganisela yezinto eziphilayo enefomula yama-molecule i-C8H9ClO, ineqembu le-chloro elifakwe esikhundleni se-para molecule ye-anisole. Ibonakala njengoketshezi olungenambala olunephunga elimnandi neliyimbali futhi yaziwa ngokusebenza kwayo kanye nokuguquguquka kwayo ekuhlanganisweni kwezinto eziphilayo. I-4-Chloroanisole isetshenziswa kakhulu njengesandulela ekwakhiweni kwamakhemikhali ahlukahlukene, okuhlanganisa imithi kanye namakhemikhali ezolimo. Izakhiwo zayo ezihlukile ziyenza ibe yigugu ezinhlotsheni eziningana zezimboni eziningi, ikakhulukazi kumakhemikhali ezokwelapha kanye nesayensi yezinto ezibonakalayo.
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4-Bromo-2-chlorophenol CAS:3964-56-5
4-I-Bromo-2-chlorophenol iyinhlanganisela yezinto eziphilayo enefomula yama-molecule C6H4BrClO. Le nhlanganisela ineqembu le-phenolic hydroxyl, i-athomu ye-bromine endaweni ye-para, kanye ne-athomu ye-chlorine endaweni ye-meta maqondana neqembu le-hydroxyl endandatho ye-benzene. Ibonakala njengento eqinile noma ekristalu futhi isetshenziswa kakhulu ekwakhiweni kwamakhemikhali njenge-intermediate eguquguqukayo. I-4-Bromo-2-chlorophenol ibalulekile kwezemithi, amakhemikhali ezolimo, kanye nesayensi yezinto ngenxa yokusabela kwayo kanye nekhono lokubamba iqhaza ezinhlobonhlobo zezimpendulo zamakhemikhali, kufaka phakathi ukufakelwa kwe-nucleophilic kanye nokusabela kokuxhuma.
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I-2-Isocyanatoethyl Acrylate CAS:13641-96-8
2-I-Isocyanatoethyl acrylate iyinhlanganisela yezinto eziphilayo enefomula yama-molecule C7H9NO2. Iyi-acrylate derivative eneqembu elisebenzayo le-isocyanate kanye neqembu le-acrylic, elinikeza izakhiwo ezihlukile zokusabela. Lolu ketshezi olungenambala kuya kophuzi olukhanyayo lwaziwa ngekhono lalo lokusebenzisa i-polymerization, okwenza lube yigugu ezinhlotsheni ezahlukene zezimboni. I-2-Isocyanatoethyl acrylate isetshenziswa kakhulu ekukhiqizweni kwezimbozo, izinamathiselo, kanye nama-elastomers. Ukusebenza kwayo kuvumela ukwakheka kwama-polymer axhumene, okuthuthukisa izici zokusebenza kwezinto, ikakhulukazi emikhakheni yezimbozo nezinamathiselo.
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I-Axitinib CAS:319460-85-0
I-Axitinib iyi-inhibitor ye-tyrosine kinase encane esetshenziswa kakhulu ekwelapheni i-advanced renal cell carcinoma (RCC). Ivimbela ngokukhetha ama-receptor e-vascular endothelial growth factor (VEGF), okuholela ekuphazanyisweni kwe-angiogenesis—ukwakheka kwemithambo yegazi emisha enikeza ama-tumors izakhamzimba nomoya-mpilo. Ngokuqondisa lezi zindlela, i-Axitinib isiza ekunciphiseni ukukhula nokuqhubekela phambili kwesimila. Ivunyelwe yiziphathimandla ezilawulayo ukuze isetshenziswe emtholampilo, imelela intuthuko ebalulekile ekwelashweni komdlavuza okuqondiwe.
