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I-2′-Deoxyuridine CAS:951-78-0
I-2′-Deoxyuridine iyi-nucleoside etholakala ku-uridine, enesici esihlukanisayo sokuba ne-athomu ye-hydrogen esikhundleni seqembu le-hydroxyl endaweni ye-2′ yoshukela we-ribose. Lokhu kuguqulwa kuyenza ibe yisisekelo esibalulekile ekwakhiweni kwe-DNA, lapho ihlangana khona ne-adenine ngesikhathi sokuhlanganiswa kwesisekelo. I-2′-Deoxyuridine idlala indima ebalulekile ekusetshenzisweni kweseli kanye nokuphindaphinda kwe-DNA. Ngaphezu kwalokho, isebenza njengesandulela sokwenziwa kwe-deoxythymidine futhi inezicelo ocwaningweni lwebhayoloji yama-molecular, ekwelapheni umdlavuza, kanye namasu okulwa namagciwane. Izakhiwo zayo ezihlukile ziyenza ibe yingxenye ebalulekile kokubili ocwaningweni oluyisisekelo nolusetshenziswayo.
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I-TERT-BUTYL ISOCYANIDE CAS:7188-38-7
I-tert-Butyl isocyanide (eyaziwa nangokuthi i-2-isocyanobutane) iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali i-C₄H₉N. Iqukethe iqembu le-tert-butyl elinamagatsha elixhunywe eqenjini elisebenzayo le-isocyanide (–N≡C). Lesi sakhiwo esiyingqayizivele sinikeza ukusabela okuphawulekayo, okwenza kube yindawo ebalulekile ekuhlanganisweni kwezinto eziphilayo. I-tert-Butyl isocyanide isetshenziswa kakhulu ekulungiseleleni amakhemikhali ahlukahlukene aqukethe i-nitrogen, okuhlanganisa imithi kanye namakhemikhali ezolimo. Izici zayo ezihlukile ziyenza ikwazi ukuhlanganyela ezindleleni eziningana ezibalulekile, okwenza kube ithuluzi eliwusizo kosokhemisi ekuthuthukisweni kwezinto ezintsha kanye nama-molecule asebenzayo.
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I-p-Toluenesulfonyl Isocyanate CAS:4083-64-1
I-p-Toluenesulfonyl isocyanate (PTSI) iyinhlanganisela yezinto eziphilayo enefomula yamakhemikhali i-C₉H₉N₂O₂S. Iqukethe iqembu le-p-toluenesulfonyl elixhunywe eqenjini elisebenzayo le-isocyanate, okwenza libe yi-reagent ebalulekile ekuhlanganisweni kwezinto eziphilayo kanye nesayensi yezinto ezibonakalayo. I-PTSI yaziwa ngokusebenza kwayo okuphezulu nokukhetha kwayo, ikakhulukazi ekuhlanganiseni nasekuhlanganisweni kwezinto eziphuma ku-urea. Ukusetshenziswa kwayo kudlulela emithini yemithi, amakhemikhali ezolimo, kanye ne-polymer chemistry. Izakhiwo ezihlukile ze-p-toluenesulfonyl isocyanate zenza kube ithuluzi elibalulekile kosokhemisi abafuna ukuthuthukisa amakhemikhali amasha anemisebenzi ethile.
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i-sodium N-lauroylsarcosinate CAS:137-16-6;7631-98-3
I-Sodium N-lauroylsarcosinate iyi-sodium salt etholakala ku-amino acid sarcosine kanye ne-lauric acid. Ngefomula yamakhemikhali i-C₁₂H₂₃NNaO₃S, yaziwa ngezakhiwo zayo ze-surfactant futhi ivame ukusetshenziswa emikhiqizweni yokunakekelwa komuntu siqu, izimonyo, kanye nezindlela zokuhlanza. Njengenhlanganisela ye-amphiphilic, i-sodium N-lauroylsarcosinate ikhombisa amakhono amahle kakhulu okukhipha amagwebu, ukuhlanganisa, kanye nokuhlanza, okwenza ifaneleke ezinhlelweni eziningi. Ubumnene bayo kanye nokuhambisana kwayo nesikhumba kwenza ibe yisithako esithandwayo ekwakhiweni okwenzelwe isikhumba esibucayi. Ukuqonda izakhiwo zayo kanye nokusetshenziswa kwayo kubalulekile ekusetshenzisweni kwayo ngempumelelo ezimbonini ezahlukene.
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![i-sodium 2-[methyl(1-oxododecyl)amino]ethanesulphonate I-CAS: 4337-75-1](https://cdn.globalso.com/xindaobiotech/14Z4YR3PJ6@V5_YM349.png)
i-sodium 2-[methyl(1-oxododecyl)amino]ethanesulphonate I-CAS: 4337-75-1
I-Sodium 2-[methyl(1-oxododecyl)amino]ethanesulphonate iyinhlanganisela yokwenziwa enezici ze-surfactant kanye ne-amphiphilic, ebonakala ngesakhiwo sayo esiyingqayizivele esihlanganisa iqembu le-sulfonate ne-derivative ye-fatty acid enochungechunge olude. Ngokusetshenziswa emikhakheni ehlukahlukene, ikakhulukazi ku-biochemistry, kwezemithi, kanye nakwezezimonyo, le nhlanganisela isebenza njenge-emulsifier, stabilizer, kanye ne-solubilizing agent ephumelelayo. Amandla ayo okuxhumana nama-lipid membranes kanye namaprotheni ayenza ibe usizo ezinhlelweni zokulethwa kwemithi kanye nezakhiwo ezihlose ukuthuthukisa ukungena kwesikhumba. Ukuqonda izakhiwo zayo zamakhemikhali kanye nezicelo zokusebenza kubalulekile ekwenzeni ngcono ukusetshenziswa kwayo emikhiqizweni ekhethekile.
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i-sodium hydrogen N-(1-oxododecyl)-L-glutamate CAS:29923-31-7;42926-22-7
I-Sodium hydrogen N-(1-oxododecyl)-L-glutamate iyinhlanganisela ye-amphiphilic ehlanganisa izakhiwo ze-fatty acid derivative ne-amino acid L-glutamate. Isakhiwo sayo esiyingqayizivele sine-fatty acid enochungechunge olude, ethuthukisa izakhiwo zayo ze-surfactant, okwenza ifaneleke ukusetshenziswa okuhlukahlukene ku-biochemistry, emithini yemithi, kanye nemikhiqizo yokunakekelwa komuntu siqu. Le nhlanganisela ingasebenza njenge-emulsifier, stabilizer, kanye ne-solubilizing agent ephumelelayo, ikhuthaza ukuhlanganiswa kwezigaba zamafutha namanzi. Ukuqonda ukuziphatha kwayo kwamakhemikhali kanye nokusetshenziswa kwayo okusebenzayo kubalulekile ekwenzeni ngcono ukusetshenziswa kwayo ekwakhiweni okukhethekile.
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I-N4-Acetylcytosine CAS:14631-20-0
I-N4-Acetylcytosine (ac4C) iyi-nucleobase eguquliwe etholakala ku-cytosine, equkethe iqembu le-acetyl elixhunywe ku-nitrogen endaweni yesine yendandatho ye-pyrimidine. Lokhu kuguqulwa kwenzeka ngokwemvelo ku-RNA futhi kuthole isithakazelo esikhulu socwaningo ngenxa yendima yalo ekulawuleni ukuvezwa kwezakhi zofuzo kanye nokuthonya imetabolism ye-RNA. I-N4-acetylcytosine ihilelekile ezinqubweni ezahlukahlukene zebhayoloji, okuhlanganisa ukuzinza kwe-mRNA, ukusebenza kahle kokuhumusha, kanye nezimpendulo zokucindezeleka kwamaseli. Ucwaningo lwe-ac4C lunikeza ukuqonda ngezindlela zomthetho ngemuva kokubhalwa futhi lugcizelela ubunzima bokuguqulwa kwe-RNA okufaka isandla ekusebenzeni kwamaseli kanye nokulawulwa kwezakhi zofuzo.
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I-Polyquaternium-10 CAS: 68610-92-4;53568-66-4
I-Polyquaternium-10 iyi-polymer ye-cationic eguquguqukayo, encibilika emanzini esetshenziswa kabanzi emikhiqizweni yokunakekelwa komuntu siqu, ikakhulukazi ekwakhiweni kwezinwele nesikhumba. Yaziwa ngezakhiwo zayo ezinhle kakhulu zokulungisa isimo, ithuthukisa ukugcinwa komswakama futhi ithuthukisa ukuthungwa kwezinwele nesikhumba. Le nhlanganisela inikeza umuzwa othambile, inciphisa ukuqina, futhi ikhulisa ukuphathwa kahle kwemikhiqizo yezinwele, okwenza ibe yisithako esidumile kuma-shampoo, ama-conditioner, kanye nezinsiza zesitayela. Ngaphezu kwalokho, i-Polyquaternium-10 ibonisa amakhono okwenza ifilimu asiza ukuvikela izinwele ekulimaleni kwemvelo ngenkathi ithuthukisa ukuzinza komkhiqizo. Izici zayo eziningi zenza ibe yisisekelo ekwakhiweni kokunakekelwa kobuhle nokomuntu siqu.
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I-Hypoxanthine CAS:68-94-0
I-Hypoxanthine iyisisekelo se-purine esenzeka ngokwemvelo esidlala indima ebalulekile ezinqubweni ezahlukene ze-biochemical, ikakhulukazi ekusetshenzisweni kwe-metabolism yama-nucleotide. Isebenza njengomxhumanisi ekuhlanganisweni nasekuwohlokeni kwama-purine, okuholela ekwakhekeni kwama-molecule abalulekile njenge-adenine ne-guanine. Ngaphezu kwalokho, i-hypoxanthine ithole isithakazelo ocwaningweni lwezokwelapha ngezicelo zayo zokwelapha ezingaba khona, okuhlanganisa izindima ekusetshenzisweni kwamandla eseli kanye nokuvikela ama-antioxidant. Ukubandakanyeka kwayo ezindleleni ze-metabolism kuyenza ibaluleke ezinqubweni ezahlukene ze-physiological, okugcizelela kakhulu ukubaluleka kwayo kokubili ku-biochemistry kanye nakwezokwelapha.
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I-Uridine CAS:58-96-8
I-Uridine iyi-nucleoside ye-pyrimidine eyakhiwe yi-uracil ye-nitrogenous base kanye ne-sugar ribose. Idlala indima ebalulekile ezinqubweni ezahlukene zezinto eziphilayo, ikakhulukazi ekwakhiweni kwe-RNA, lapho isebenza khona njengenye yezinto ezibalulekile zokwakha. I-Uridine ayigcini nje ngokubamba iqhaza ekusetshenzisweni kwe-metabolism yamaseli kodwa futhi ihlolwe ngemiphumela yayo engaba khona yokwelapha, okuhlanganisa ukuvikela izinzwa kanye nokuthuthukiswa kwengqondo. Izinto eziphuma kuyo zisetshenziswa ekwakhiweni kwemithi, ikakhulukazi ekwelapheni izifo zezinzwa kanye nezifo ze-metabolic. Njengoba ucwaningo luqhubeka nokwembula izindima zalo eziningi, i-uridine iyaqashelwa kokubili ku-biochemistry kanye ne-pharmacology.
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I-Fluorocytosine CAS:2022-85-7
I-Fluorocytosine, eyaziwa nangokuthi i-5-fluorocytosine (5-FC), iyi-ejenti yokukhunta esetshenziswa kakhulu ekwelapheni izifo zesikhunta ezihambisana nomzimba, ikakhulukazi lezo ezibangelwa izinhlobo ze-Candida ne-Cryptococcus. Isebenza njenge-antimetabolite, ivimbela ukukhula kwesikhunta ngokuphazamisa ukwakheka kwe-nucleic acid. Lo muthi uthole ukubaluleka ezindaweni zemitholampilo, ikakhulukazi ekwelapheni i-cryptococcal meningitis ezigulini ezine-immunocompromised, njengalezo ezine-HIV/AIDS. Nakuba isebenza kahle, i-fluorocytosine ivame ukusetshenziswa kanye nezinye izidakamizwa zokukhunta ukuze kuthuthukiswe ukusebenza kahle kokwelapha nokunciphisa ingozi yokumelana.
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I-D(-)-Ribose CAS:50-69-1
I-D(-)-ribose ushukela otholakala ngokwemvelo, ikakhulukazi i-pentose monosaccharide, edlala indima ebalulekile ekusetshenzisweni kwamaseli. Iyingxenye ebalulekile ye-ATP (adenosine triphosphate), umthwali wamandla oyinhloko kuwo wonke amaseli aphilayo, okwenza kube lula izinqubo ezibalulekile ze-biochemical njengokukhiqizwa kwamandla kanye nokuhlanganiswa kwe-nucleic acid. I-D(-)-ribose nayo ibalulekile ekwakhiweni kwama-nucleotide nama-nucleic acid, okwenza ibaluleke kakhulu kuzo zombili izakhiwo ze-DNA kanye ne-RNA. Ngaphandle kwezindima zayo ze-metabolic, i-D(-)-ribose ithole ukunakwa ocwaningweni lwezokwelapha ngezinzuzo zayo ezingaba khona ekuthuthukiseni amazinga wamandla amaseli kanye nokuthuthukisa ukululama ekuzivocavoceni.
