I-Boc-MeIle-OH CAS:52498-32-5

I-Boc-MeIle-OH isetshenziswa kakhulu ekuhlanganisweni kwe-peptide yesigaba esiqinile ukudala ama-peptide aklanywe ngokwezifiso anezinhlu ezithile kanye nokusebenza. Njengendlela evikelwe ye-N-methyl-isoleucine, ivumela ukufakwa okulawulwayo kwezinsalela ze-N-methyl-isoleucine ku-peptide chain ekhulayo, ivimbela ukusabela okungathandeki okungathandeki futhi ivumela ukuhlanganiswa kwama-peptide ayinkimbinkimbi anezakhiwo ezilungiselelwe. Ku-bioconjugation kanye ne-chemistry biology, i-Boc-MeIle-OH isebenza njengesakhiwo esiguquguqukayo sokudala ama-peptide asebenzayo, ama-probe anelebula, kanye ne-peptide-based therapeutics. Ukusetshenziswa kwayo kwenza ukuguqulwa okunembile kwama-peptide namaprotheni, kusiza ukuthuthukiswa kwama-molecule amaningi anokuqina okuthuthukisiwe, ukucaciswa okuqondiwe, noma amakhono okuthwebula izithombe zezinhlelo zokusebenza ezahlukahlukene ze-biomedical. Ngaphezu kwalokho, ekutholakaleni kwemithi kanye nokuthuthukiswa kokwelapha, i-Boc-MeIle-OH isetshenziswa ukudala ama-peptide conjugates nama-peptide aguquliwe anamaphrofayili e-pharmacokinetic athuthukisiwe kanye nemisebenzi ye-biological. Lokhu kuguqulwa kungathuthukisa ukusebenza kahle, ukukhetha, kanye nokulethwa kwemithi esekelwe kuma-peptide, okufaka isandla ekuthuthukisweni kwemithi enembile kanye nemithi yokwelapha eqondiwe. Sekukonke, ukuthembeka kanye nokuguquguquka kwe-Boc-MeIle-OH ekuhlanganisweni kwe-peptide kanye ne-bioconjugation kwenza kube ithuluzi elibalulekile lokuthuthukisa ucwaningo ekutholakaleni kwezidakamizwa, i-chemistry biology, kanye ne-proteomics, okunikeza amathuba ahlukahlukene okuthuthukisa izinhlelo zokusebenza ezintsha ze-biomedical.