I-H-Asp-(OBzl)-OBzl·TOS CAS:2886-33-1

I-H-Asp-(OBzl)-OBzl·Tos idlala indima ebalulekile ekwakhiweni kwe-peptide, lapho amaqembu avikela i-benzyl ester kanye nokusebenza kwe-tosyl kusiza ukuvimbela ukusabela okungathandeki ngesikhathi sokuhlanganiswa kwama-peptide aqukethe izinsalela ze-aspartic acid. Lokhu kwenza kube lula ukulungiselela ama-peptide aguquliwe okutadisha ukusebenzisana kwamaprotheni, ubudlelwano be-enzyme-substrate, kanye nobudlelwano besakhiwo nomsebenzi. Ngaphezu kwalokho, le nhlanganisela ithola ukusetshenziswa ekwakhiweni kwe-peptide yesigaba esiqinile, indlela eyisisekelo ekhemistri ye-peptide kanye nemizamo yokuthola izidakamizwa, okuvumela ukuthuthukiswa kwama-peptide amasha kanye nama-peptidomimetics anezicelo zokwelapha ezingaba khona. Ngaphezu kwalokho, i-H-Asp-(OBzl)-OBzl·Tos inegalelo ekuthuthukiseni ukuqonda kwethu ubudlelwano besakhiwo nomsebenzi we-peptide futhi isebenza njengengxenye ebalulekile ekuhlolweni kwezici ezahlukahlukene zesayensi ye-peptide. Ukusetshenziswa kwayo kudlulela ophenyweni lwe-bioconjugation kanye ne-biology yamakhemikhali, okusiza ukuhlanganiswa kwama-peptide kwamanye ama-molecule ukuze kunikezwe noma kuhlolwe okuqondiwe. Sekukonke, kumi njengethuluzi elibalulekile, okuvumela abacwaningi ukuthi bahlole ubunzima be-peptide chemistry kanye nemiphumela yayo ocwaningweni lwezokwelapha, ekuthuthukisweni kwemithi, kanye nokungenelela okungenzeka kokwelapha. Ngezinhlelo zayo eziningi ocwaningweni lwe-peptide, le reagent inenani elikhulu ekuthuthukiseni ulwazi lwesayensi kanye nokufaka isandla ekuthuthukisweni kwemithi yokwelapha esekelwe kwi-peptide.