I-Boc-Ile-ONp CAS:16948-38-2

I-Boc-Ile-ONp isetshenziswa kabanzi emasu okuhlanganisa i-bio kanye nezinqubo zokuguqula i-peptide. Ekuhlanganisweni kwe-peptide, yenza kube lula ukufakwa okulawulwayo kwezinsalela ze-isoleucine kuchungechunge lwe-peptide, okuvumela ukunamathiswa okuqondiwe kwamaqembu ahlukahlukene asebenzayo, amalebula, noma ama-molecule ukuze kusetshenziswe izinhlelo ezahlukene. Lokhu kuguqulwa okukhethiwe kuvumela ukudalwa kwama-peptide asebenzayo amaningi anezakhiwo ezilungiselelwe, njengokuqina okuthuthukisiwe, ukucaciswa kwenhloso, noma amakhono okuthwebula izithombe. Ocwaningweni lwe-proteomics, i-Boc-Ile-ONp ivumela ukulebula kwamaprotheni nama-peptide endaweni ethile, okufaka isandla ekuhlaziyweni kwesakhiwo, izifundo zokusebenzisana, kanye nokuhlolwa okusekelwe ku-mass spectrometry. Ukunamathiswa okulawulwayo kwe-Boc-Ile-ONp kuzinsalela ze-isoleucine kwenza kube lula ukuchaza okunembile kanye nokuhlaziywa kokusebenza kwamaprotheni nama-peptide, kusekela intuthuko ekuqondeni izinhlelo zezinto eziphilayo kanye nezindlela zesifo. Ngaphezu kwalokho, ekuthuthukisweni kwemithi, i-Boc-Ile-ONp idlala indima ebalulekile ekuhlanganiseni izinto zokwelapha kuma-peptide noma ama-protein, ukudala izinhlelo zokulethwa kwemithi eziqondiwe, ama-antibody-drug conjugates, noma izakhiwo zomuthi wokugoma ezinamaphrofayili e-pharmacokinetic athuthukisiwe kanye nemiphumela encishisiwe engaqondiwe. Sekukonke, ukuthembeka kwe-Boc-Ile-ONp kanye nokuguquguquka kwayo ekuguqulweni kwe-peptide kanye ne-bioconjugation kwenza kube ithuluzi elibalulekile lokuthuthukisa ucwaningo ekutholakaleni kwezidakamizwa, i-chemistry biology, kanye ne-proteomics, okunikeza amathuba ahlukahlukene okuthuthukisa izinhlelo zokusebenza ezintsha ze-biomedical.