1,4-Dithioerythritol (DTE) CAS:6892-68-8

I-ejenti Yokunciphisa: I-DTE ijwayele ukusetshenziselwa ukuphula izibopho ze-disulfide kuma-molecule.Inganciphisa izinhlanganisela ezine-disulfide efomini yazo ye-thiol, ivumele abacwaningi ukuthi bafunde isimo esincishisiwe samaprotheni, ama-peptide, namanye ama-biomolecules.Lokhu kubaluleke kakhulu ekuhlanzeni amaprotheni nasekulungiseleleni isampula, njengoba kusiza ukuvimbela ukuhlangana kwamaprotheni nokugcina ukuqina kwamaprotheni.

I-Protein Denaturation: I-DTE ingasetshenziselwa ukuguqula amaprotheni ngokuphazamisa ukwakheka kwawo okuphezulu.Lokhu kuwusizo ocwaningweni lwamaprotheni lapho kudingeka ukwembuleka nokuphinda kugoqelwe, njengokunquma kinetics yokugoqa amaprotheni noma ukuphenya ukusebenzisana kwamaprotheni namaprotheni.

I-Antioxidant: I-DTE inezindawo zokulwa ne-antioxidant futhi ingasusa ama-radicals mahhala kanye nezinhlobo ze-oxygen esebenzayo (ROS).Isiza ukuvikela amaseli nama-biomolecules emonakalweni we-oxidative obangelwa i-ROS.I-DTE ingasetshenziswa ocwaningweni lwesiko lamaseli ukutadisha imiphumela yengcindezi ye-oxidative kumaseli kanye nokuhlola umsebenzi we-antioxidant.

Izifundo Zokuvimbela Ama-Enzyme: I-DTE ivame ukusetshenziswa njengesilawuli esingalungile noma isivimbeli ezifundweni zokuvimbela ama-enzyme.Ngokuvimbela ngokungenakulungiseka indawo esebenzayo ye-enzyme, isiza abacwaningi ukunquma okucacile kanye nendlela yokuvinjelwa kwe-enzyme ngezinye izinhlanganisela.

Ukwenziwa kwamakhemikhali: I-DTE ingasetshenziswa ekuhlanganiseni amakhemikhali njenge-ejenti enciphisa ukuguqulwa kwezinhlanganisela ze-carbonyl zibe otshwaleni bazo obuhambisanayo.Iwusizo ikakhulukazi ku-asymmetric synthesis, lapho i-stereoselectivity ifunwa khona.