1,4-Dithioerythritol (DTE) CAS:6892-68-8

I-Reducing Agent: I-DTE ivame ukusetshenziselwa ukuphula izibopho ze-disulfide kuma-molecule. Inganciphisa ama-compounds aqukethe i-disulfide abe yi-thiol form yawo, okuvumela abacwaningi ukuthi batadishe isimo esinciphile samaprotheni, ama-peptide, kanye namanye ama-biomolecule. Lokhu kuwusizo kakhulu ekuhlanzweni kwamaprotheni kanye nokulungiselela isampula, njengoba kusiza ukuvimbela ukuhlanganiswa kwamaprotheni nokugcina ukuqina kwamaprotheni.

Ukuguquka Kwamaprotheni: I-DTE ingasetshenziswa ukuphazamisa isakhiwo sawo sesithathu. Lokhu kuyasiza ezifundweni zamaprotheni lapho kudingeka khona ukuvuleka nokugoqana kabusha, njengokunquma i-kinetics yokugoqa amaprotheni noma ukuphenya ukusebenzisana kwamaprotheni namaphrotheni.

I-Antioxidant: I-DTE inezakhiwo ze-antioxidant futhi ingasusa ama-free radical kanye nezinhlobo ze-reactive oxygen (ROS). Isiza ukuvikela amaseli nama-biomolecule emonakalweni we-oxidative obangelwa yi-ROS. I-DTE ingasetshenziswa ekuhlolweni kokukhula kwamaseli ukutadisha imiphumela yokucindezeleka kwe-oxidative kumaseli nokuhlola umsebenzi we-antioxidant.

Izifundo Zokuvimbela Ama-enzyme: I-DTE ivame ukusetshenziswa njengokulawula okungekuhle noma isithiyo ezifundweni zokuvimbela ama-enzyme. Ngokuvimbela ngokungenakuguqulwa indawo esebenzayo ye-enzyme, kusiza abacwaningi ukunquma ukucaciswa kanye nendlela yokuvimbela ama-enzyme ngamanye ama-compound.

Ukwenziwa kwamakhemikhali: I-DTE ingasetshenziswa ekuhlanganisweni kwamakhemikhali njenge-ejenti yokunciphisa ukuguqulwa kwamakhemikhali e-carbonyl abe yi-alcohols yawo ehambisanayo. Iwusizo kakhulu ekuhlanganisweni okungalingani, lapho kudingeka khona ukukhetha kwe-stereo.