I-Z-Lys(Z)-ONp CAS:21160-82-7

I-Z-Lys(Z)-ONp isetshenziswa kumakhemikhali e-peptide njenge-reagent eyinhloko yokwenziwa kwama-peptide. Isebenza njenge-ejenti yokuhlanganisa, ikhuthaza ukwakheka kwezibopho ze-peptide phakathi kwama-amino acid residues ngesikhathi sokwenziwa kwe-peptide yesigaba esiqinile (i-SPPS) kanye nokwakheka kwe-peptide yesigaba sesisombululo. Abacwaningi kanye nosokhemisi bavame ukusebenzisa i-Z-Lys(Z)-ONp ukuguqula noma ukwandisa amaketanga e-peptide, okuvumela ukudalwa kokulandelana kwe-peptide ngokwezifiso ngokulawula okunembile ukwakheka kwe-amino acid. Ngaphezu kokwenziwa kwe-peptide, i-Z-Lys(Z)-ONp ithola ukusetshenziswa ekuthuthukisweni kwezindlela zokwelapha ezisekelwe ku-peptide, lapho ukulawula okunembile isakhiwo se-peptide kubalulekile emsebenzini wezinto eziphilayo kanye ne-pharmacokinetics. Ubumsulwa bayo obuphezulu kanye nokuqina kwayo kwenza kube yingxenye ebalulekile ekukhiqizweni kwama-peptide asezingeni eliphezulu ocwaningo lwemithi kanye nentuthuko. Ngaphezu kwalokho, i-Z-Lys(Z)-ONp isetshenziswa ezifundweni ze-biochemical kanye ne-biophysical ukuphenya ukusebenzisana kwamaprotheni namaphrotheni, i-enzyme kinetics, kanye nobudlelwano besakhiwo nomsebenzi. Ukuguquguquka kwayo kanye nokuthembeka kwayo kwenza kube ithuluzi elibalulekile kososayensi abahlola izindima ezahlukahlukene zama-peptide namaprotheni ezinhlelweni zezinto eziphilayo. Sekukonke, i-Z-Lys(Z)-ONp idlala indima ebalulekile ekuthuthukiseni ucwaningo kanye nokusungula izinto ezintsha emikhakheni ye-biochemistry, yezemithi, kanye ne-biology yamakhemikhali, okwenza ososayensi nabacwaningi bakwazi ukuhlola amandla amakhulu amakhemikhali asekelwe kuma-peptide ngezinjongo zokwelapha nezesayensi.