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I-Venlafaxine CAS:93413-69-5
I-Venlafaxine iyi-antidepressant yesigaba se-serotonin ne-norepinephrine reuptake inhibitor (SNRI).Lo muthi wasungulwa okokuqala ngu-Wyeth ku-19Chemicalbook93 futhi manje usumakethwa ngabakwaPfizer.Lesi sidakamizwa sigunyazwe ukwelashwa kwe-depressive disorder enkulu (MDD), ukuphazamiseka kokukhathazeka okujwayelekile (GAD), nokucindezeleka okuhambisana nokukhathazeka.
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I-β-Nicotinamide Mononucleotide CAS:1094-61-7
I-Nicotinamide mononucleotide (NMN), umkhiqizo wokusabela kwe-NAMPT kanye nokhiye we-NAD+ omaphakathi, ithuthukisa ukungabekezelelani kwe-glucose ngokubuyisela amazinga e-NAD+ kumagundane e-T2D enziwe yi-HFD.I-NMN iphinde ithuthukise ukuzwela kwe-insulin yesibindi futhi ibuyisele ukubonakaliswa kofuzo okuhlobene nengcindezi ye-oxidative, impendulo yokuvuvukala, nesigqi se-circadian, ngokwengxenye ngokusebenzisa i-SIRT1.I-NMN isetshenziselwa ukutadisha ama-motifs abophayo ngaphakathi kwama-aptamers e-RNA kanye nezinqubo zokuvula i-ribozyme ezibandakanya izingcezu ze-RNA ezicushiwe ze-β-nicotinamide mononucleotide (β-NMN).
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I-β-Nicotinamide Adenine Dinucleotide CAS:53-84-9
I-β-Nicotinamide adenine dinucleotide (NAD) iwuhlobo lwe-oxidized ye-β-Nicotinamide Adenine Dinucleotide.Ikhona njenge-anion ngaphansi kwezimo ezivamile ze-physio-logic.Ihlobene ngokusebenza ne-deamido-NAD zwitterion.Isisekelo se-conjugate se-NAD(+).Itholakala kabanzi endalweni futhi ibandakanyeka ekuphenduleni okuningi kwe-enzymatic lapho isebenza khona njengesithwali se-electron ngokushintshwa nge-oxidized (NAD+) kanye nokunciphisa (NADH).
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I-β-Nicotinamide Adenine Dinucleotide, ifomu elincishisiwe CAS:606-68-8
I-β-Nicotinamide adenine dinucleotide (NAD+) kanye ne-β-Nicotinamide adenine dinucleotide, encishisiwe (NADH) ihlanganisa i-coenzyme redox pair (NAD+:NADH) ehilelekile ekuphenduleni okubanzi kokunciphisa i-enzyme catalyzed oxidation.Ngokungeziwe emsebenzini wayo we-redox, i-NAD+/NADH ingumnikeli wamayunithi e-ADP-ribose ku-ADP-ribosylaton (ADP-ribosyltransferases; poly(ADP-ribose) polymerases ) ukusabela kanye nomanduleli we-cyclic ADP-ribose (ADP-ribosyl cyclases) .
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I-β-Nicotinamide Adenine Dinucleotide Phosphate Tetrasodium Usawoti, ifomu elincishisiwe CAS:2646-71-1
I-NADPH iwuhlobo oluncishisiwe lwe-coenzyme NADP+;esetshenziswa ekuphenduleni kwe-anabolic njenge-lipid ne-nucleic acid synthesis, edinga i-NADPH njenge-ejenti yokunciphisa.I-NADPH, i-Tetrasodium Salt iyi-coenzyme etholakala yonke indawo esebenza njenge-electron donor ekuphenduleni okuningi kusetshenziswa i-dehydrogenase kanye ne-reductase enzymes.Ikhiqizwa ngokuncishiswa kwe-electron eyamukela i-NADP+.Izindlela zebhayoloji ezilandelayo zibandakanya i-NADPH: ukwakheka kwe-carbohydrate esuka ku-CO2 ngesikhathi se-photosynthesis, ukugcinwa kwamazinga aphezulu e-glutathione encishisiwe ku-erythrocytes, ukunciphisa i-thioredoxin.
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I-Thio-Nicotinamide Adenine Dinucleotide (Thio-NAD) CAS:4090-29-3
I-Thionicotinamide adenine dinucleotide iyi-analog ye-NAD.Ukusetshenziswa kwe-Thio-NAD esikhundleni se-NAD njenge-substrate yama-enzyme adla i-NAD(+) kunenzuzo enkulu njengoba uhlobo oluncishisiwe lwe-Thio-NAD lubonisa ukwanda okukhulu kokumunca ku-405 nM, ubude begagasi obutholakala kakhulu kubafundi be-microplate.
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I-β-Nicotinamide Adenine Dinucleotide Phosphate Monosodium Salt CAS:1184-16-3
I-Nicotinamide adenine dinucleotide phosphate, efushanisiwe i-NADP+ noma, ekubhalweni kwakudala, i-TPN (triphosphopyridine nucleotide), iyi-cofactor esetshenziswa ekuphenduleni kwe-anabolic, njengomjikelezo we-Calvin kanye ne-lipid ne-nucleic acid syntheses, edinga i-NADPH njenge-ejenti yokunciphisa ('umthombo we-hydrogen. ').Isetshenziswa yizo zonke izinhlobo zempilo yamaselula.
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I-Ciclopirox Ethanolamine CAS:41621-49-2 Umkhiqizi Supplier
I-Ciclopirox ethanolamine iyi-ejenti ebanzi ye-antigfungal, futhi ibonisa umsebenzi we-antibacterial ngokumelene nama-bacteria amaningi e-Gram-positive kanye ne-Gram-negative, futhi inezici zokuqeda ukuvuvukala.Isetshenziswa ekwelapheni i-topical yesikhumba se-fungal ne-nail infections.
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I-Desvenlafaxine Succinate CAS:386750-22-7
I-Desvenlafaxine Succinate iyi-dual serotonin kanye ne-norepinephrine reuptake inhibitor (SNRI) eyagunyazwa ukwelashwa kwe-depressive disorder (MDD) e-United States ngo-2008. Ukuze kuthuthukiswe ukusebenza kahle nokuphepha kwephrofayili ye-venlafaxine, u-Wyeth wathola futhi wasungula eyodwa. Ama-metabolites amakhulu e-venlafaxine, okuyi-O-desmethyl metabolite (desvenlafaxine).
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I-Doxazosin Mesylate CAS:77883-43-3 Umhlinzeki Womkhiqizi
I-Doxazosin mesylate iyinhlanganisela ye-quinazoline eyi-inhibitor ekhethiwe ye-alpha1 subtype ye-alpha adrenergic receptors.I-Doxazosin mesylate isizukulwane esisha se-quinazolone α1 receptor blocker eyakhiwe yinkampani ye-Pfizer (United States), Inesigamu sempilo ende, yenza imiphumela yayo yokunweba imithambo yegazi, inciphise ukumelana nemithambo kanye nokwehlisa umfutho wegazi ngokuvimbela imithambo yegazi. i-receptor engu-1.Kuye kwatuswa emazweni angaphandle njengemithi yomtholampilo yokuqala ye-anti-hypertension kanye nokwelashwa kwesifo se-prostate.
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L-Isoleucine CAS:73-32-5 Umkhiqizi Supplier
I-L-Isoleucine, eyaziwa nangokuthi i-Isoleucine, i-amino acid eyi-isomer ye-leucine.Ibalulekile ekuhlanganiseni kwe-hemoglobin kanye nokulawulwa koshukela egazini kanye namazinga wamandla.I-L-Isoleucine iyi-isomer ye-L-leucine futhi iyi-amino acid ebalulekile.Ihlanganiswe kusuka ku-threonine futhi iyi-branched-chain hydrophobic amino acid.
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Captopril CAS:62571-86-2 Umkhiqizi Supplier
I-Captopril ingumuthi ocwaningwe kakhulu kuma-angiotensin-converting enzyme inhibitors ophakanyiswe njengomuthi we-antihypertensive.Ivimbela i-angiotensin-converting enzyme, ecindezela ukwakheka kwe-angiotensin II futhi ikhulule umphumela wayo we-vasoconstricting emithanjeni ye-arterial kanye ne-venous.Sekukonke ukungezwani kwe-vascular peripheral kuyancipha, okuholela ekwehleni komfutho we-arterial.
