I-Venlafaxine CAS:93413-69-5

I-Venlafaxine iyisidakamizwa sokucindezeleka sesigaba se-serotonin kanye ne-norepinephrine reuptake inhibitor (SNRI). Lesi sidakamizwa saqala ukwenziwa nguWyeth ku-19Chemicalbook93 futhi manje sithengiswa yi-Pfizer. Lesi sidakamizwa sivunyelwe ukwelapha isifo sokucindezeleka esikhulu (MDD), isifo sokukhathazeka esijwayelekile (GAD), kanye nokucindezeleka okuhambisana nokukhathazeka.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

I-Venlafaxine ingavimbela ukuphinda kuthathwe kwe-NA kanye ne-5-HT, futhi ivimbele kancane ukuphinda kuthathwe kwe-dopamine. Ukuvinjelwa kwe-in vitro kwama-receptor e-cholinergic, ama-receptor e-histamine α Womabili ama-receptor awanayo i-affinity. Ukumuncwa kwesisu kuhle, futhi i-Chemicalbook iguqulwa yi-cytochrome P45011D6 esibindini futhi ikhishwa ngumchamo. I-t1/2 yama-metabolites asebenzayo ayinhloko isukela emahoreni ama-5 kuya kwangu-11. Ngemuva kwamasonto ama-3, ukuhlushwa kwesimo esizinzile kwafinyelelwa. Kusetshenziselwa ukwelapha ukucindezeleka.

Isampula Yomkhiqizo

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C17H27NO2
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe ekristalu
Inombolo ye-CAS	93413-69-5
Ukupakisha	25KG
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.