I-Letrozole CAS:112809-51-5 Isithombe Esifakiwe Somhlinzeki Womkhiqizi

I-Letrozole CAS:112809-51-5 Umkhiqizi Womhlinzeki

I-Letrozole iyingxenye yesizukulwane esisha se-aromatase inhibitors ekhethwa kakhulu futhi iwukuphuma kokwenziwa kwe-benzotriazole.I-Letrozole ivimbela i-aromatase ekunciphiseni amazinga e-estrogen, ngaleyo ndlela ivimbele i-estrogen ekukhuthazeni ukukhula kwesimila.Umsebenzi wayo we-vivo unamandla izikhathi ezingu-150-250 kunowesizukulwane sokuqala se-aromatase inhibitor i-Amarante.Njengoba ikhetha kakhulu, ngeke ithinte i-glucocorticoid, i-mineralocorticoid kanye nemisebenzi ye-thyroid;ngisho nangemithamo ephezulu, ngeke ibe nemiphumela evimbela ekukhiqizweni kwe-adrenal corticosteroid, inikeze inkomba ephezulu yokwelashwa.

Oda noma Cela I-Quote

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isicelo kanye Nomphumela

I-Letrazole ingahlanganiswa ngezinyathelo ezimbili ukusuka ku-4- bromomethyl-benzonitrile ne-1,2,4-triazole futhi iyisizukulwane sesithathu se-aromatase inhibitor.Kuyi-inhibitor ethize kakhulu ye-P450arom evimbela ukuguqulwa kwe-androstenedione ku-estrone.Ukwehliswa kwe-plasma estrogen kwakushesha futhi kuthatha isikhathi eside.Lokhu kufezwa ngaphandle kokuvinjelwa kwenye i-steroid biosynthesis okwenza kube i-aromatase inhibitor ekhethiwe kakhulu ehlolwe.I-Letrazole inomsebenzi ophawulekayo we-antitumor, ibekezelelwa kahle futhi ayinayo imiphumela emibi enobuthi.Inamandla aphindwe izikhathi ezingu-10,000 kune-aminoglutethimide, ku-vivo, i-aromatase inhibitor yokuqala esungulwe kahle.

Isampula Lomkhiqizo

Ukupakishwa komkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	I-C17H11N5
Isivivinyo	99%
Ukubukeka	Impushana emhlophe
Inombolo ye-CAS.	112809-51-5
Ukupakisha	25KG
I-Shelf Life	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	ISO.