Itraconazole CAS: 84625-61-6 Umhlinzeki Womkhiqizi

I-Itraconazole iyi-ejenti yokulwa namagciwane ye-triazole. Isetshenziselwa ukuvimbela ama-enzyme ancike ku-cytochrome P-450 kanye nokwakheka kwe-ergosterol. Isetshenziswe ngokumelene ne-histoplasmosis, i-blastotomycosis, i-cryptococcal meningitis, kanye ne-aspergillosis. Izindlela zayo ezahlukene zisetshenziselwa ukufunda izinhlobo ze-Candida ezifweni ezihlaselayo ze-murine. Isetshenziswe ukutadisha izinguquko ezandayo ze-forestomach mucosa kumagundane anesifo sikashukela abangelwa yi-alloxan. Ukwelapha izifo ezilandelayo ze-fungus ezigulini ezine-immunocompromised kanye nezinganayo i-immunocompromised: i-pulmonary and extrapulmonary blastomycosis, i-histoplasmosis, i-aspergillosis, kanye ne-onychomycosis.