I-Itraconazole CAS:84625-61-6 Umkhiqizi Womhlinzeki

I-Itraconazole iyi-ejenti ye-antifungal ye-triazole.Isetshenziselwa ukuvimbela ama-enzyme ancike ku-cytochrome P-450 kanye nokuhlanganiswa kwe-ergosterol.Isetshenziswe ngokumelene ne-histoplasmosis, i-blastomycosis, i-cryptococcal meningitis, ne-aspergillosis.Ukwakheka kwayo okuhlukile kusetshenziselwa ukutadisha izinhlobo ze-Candida ezifweni ezihlasela i-murine.Isetshenziselwe ukutadisha izinguquko ezikhulayo ze-forestomach mucosa kumagundane esifo sikashukela esibangelwa i-alloxan.Ukwelashwa kwezifo ezilandelayo zefungal ezigulini ezingenakuzivikela kanye nezingenayo i-immunocompromised: i-blastomycosis yamaphaphu kanye ne-extrapulmonary, i-histoplasmosis, i-aspergillosis, ne-onychomycosis.