I-HATU CAS:148893-10-1 Intengo Yomkhiqizi

Ukusebenza kwamaqembu e-carboxyl: I-HATU isebenza njengesiqalisi esihle kakhulu samaqembu e-carboxyl, okuvumela ukuhlangana okuphumelelayo namaqembu e-amino. Isiza ukwakheka kwezibopho ze-peptide ezizinzile kakhulu phakathi kwama-amino acid.

Ukusebenza kahle kokuhlanganisa okuphezulu: I-HATU yaziwa ngokusebenza kahle kwayo kokuhlanganisa okuphezulu, okuholela ekuvuneni okuphezulu komkhiqizo we-peptide ofiselekayo. Ukusetshenziswa kwe-HATU kungasiza ekunciphiseni ukusabela okungekuhle futhi kuthuthukise ukusebenza kahle kwenqubo yokwenziwa kwe-peptide.

Ukuguquguquka: I-HATU ingasetshenziswa ezindleleni ezahlukene zokwenziwa kwe-peptide, okuhlanganisa kokubili ukwenziwa kwe-solution-phase kanye nokwenziwa kwe-solid-phase. Ibonisa ukuhambisana nohlu olubanzi lwe-amino acid derivatives, okuvumela ukwenziwa kwe-peptide sequences ehlukahlukene.

Izimo zokusabela okuncane: Ukusabela kokuxhumanisa kwe-HATU kungenziwa ngaphansi kwezimo eziphansi, njengokushisa kwegumbi noma amazinga okushisa aphezulu kancane. Lesi sici sinenzuzo njengoba sinciphisa ingozi yokusabela okungafuneki futhi sigcina ubuqotho bamaqembu asebenzayo abucayi ku-peptide ekhiqizwayo.

Ukuzinza: I-HATU iyi-reagent ezinzile engagcinwa isikhathi eside ngaphandle kokuwohloka okukhulu noma ukulahlekelwa ukusabela. Lokhu kuvumela ukusetshenziswa okulula kanye nokugcinwa kwesikhathi eside, okwenza kube ukukhetha okusebenzayo kwabacwaningi ekuhlanganisweni kwama-peptide.

Ukukhetha kanye nobumsulwa: Ukusetshenziswa kwe-HATU kuvame ukuphumela ekukhetheni okuphezulu kanye nobumsulwa bama-peptide ahlanganisiwe. Lokhu kubaluleke kakhulu ocwaningweni lwezokwelapha kanye ne-biology lapho i-peptide eqondiwe idinga ukutholakala ihlanzekile kakhulu ukuze kuqhutshekwe nokufundwa noma ukusetshenziswa.