I-D-fucose CAS:3615-37-0 Intengo Yomkhiqizi

I-D-fucose iyi-monosaccharide, ikakhulukazi ushukela we-carbon ayisithupha, ongoweqembu loshukela olula olubizwa ngokuthi ama-hexoses. Iyi-isomer ye-glucose, ehlukile ekubunjweni kweqembu elilodwa le-hydroxyl.

I-D-fucose itholakala ngokwemvelo ezintweni eziphilayo ezahlukahlukene, okuhlanganisa amabhaktheriya, isikhunta, izitshalo, kanye nezilwane. Idlala indima ebalulekile ezinqubweni eziningana zezinto eziphilayo, njengokubonisana kwamaseli, ukunamathela kwamaseli, kanye nokwakheka kwama-glycoprotein. Iyingxenye yama-glycolipids, ama-glycoprotein, kanye nama-proteoglycans, ahilelekile ekuxhumaneni nasekuqaphelweni kwamaseli.

Kubantu, i-D-fucose nayo ihilelekile ekwakhiweni kwezakhiwo ezibalulekile ze-glycan, njenge-Lewis antigens kanye ne-antigens yeqembu legazi, okunomthelela ekuvumelaneni kwegazi kanye nokuzwela ezifweni.

I-D-fucose ingatholakala emithonjeni eyahlukahlukene, okuhlanganisa ulwandle, izitshalo, kanye nokubiliswa kwamagciwane. Isetshenziswa ocwaningweni kanye nasekusetshenzisweni kwezokwelapha, kanye nasekukhiqizweni kwemithi ethile kanye namakhemikhali okwelapha.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

Imiphumela Yokulwa Nokuvuvukala: I-D-fucose iboniswe ukuthi inezakhiwo zokulwa nokuvuvukala. Ingavimbela ukukhiqizwa kwama-cytokine abangela ukuvuvukala futhi inciphise ukusebenza kwamaseli omzimba, ngaleyo ndlela inikeze izinzuzo zokwelapha ezimweni zokuvuvukala.

Imiphumela Yokulwa Nomdlavuza: I-D-fucose ibonise imisebenzi yokulwa nomdlavuza ngokuvimbela ukwanda kwamaseli omdlavuza, okubangela i-apoptosis (ukufa kwamaseli), kanye nokucindezela ukukhula kwesimila. Ingaphinde iguqule ukubonakaliswa kwezakhi zofuzo ezihilelekile ekulawulweni komjikelezo weseli kanye nokusabalala kwamangqamuzana.

Imiphumela Yokuguquguqula Amasosha omzimba: I-D-fucose ingathonya izimpendulo zamasosha omzimba ngokushintsha imisebenzi yamangqamuzana omzimba. Kuye kwabonakala ukuthi ithuthukisa umsebenzi we-phagocytic wama-macrophage, ivuselela ukukhiqizwa kwama-antibodies, futhi ithuthukise ukuxhumana kwamaseli omzimba.

Imiphumela Yokulwa Namagciwane: I-D-fucose ibonisa izakhiwo zokulwa namagciwane ngokumelene namagciwane ahlukahlukene. Ingavimbela ukunamathela kwamagciwane kumaseli abambe iqhaza, ngaleyo ndlela ivimbele ukwakheka kwe-biofilm futhi inciphise ingozi yokutheleleka ngamagciwane.

Ukuvinjelwa kwe-Glycosylation kanye ne-Glycosylation: I-D-fucose idlala indima ebalulekile ezinqubweni ze-glycosylation, okubandakanya ukunamathiswa koshukela kumaprotheni noma ama-lipid. Ihilelekile ekwakhiweni kwama-glycoprotein, ama-glycolipid, kanye namanye ama-carbohydrate ayinkimbinkimbi. Ama-analog noma ama-inhibitor e-D-fucose angasetshenziswa ukuphazamisa izinqubo ze-glycosylation, okungase kuthinte imisebenzi yamaseli kanye nezimo ze-pathological.

Ukusetshenziswa Kwezokwelapha Nokwelapha: I-D-fucose kanye nezinto ezitholakala kuyo zisetshenziswa ezinhlotsheni ezahlukene zezokwelapha nezokwelapha. Zisetshenziswa njengezinto zokusetshenziswa ekukhiqizweni kwemithi, ikakhulukazi imithi yokulwa namagciwane kanye nemithi yokucindezela amasosha omzimba. Amakhemikhali nama-conjugates asekelwe ku-D-fucose nawo ayafundwa ukuze asetshenziswe njengezinhlelo zokulethwa kwemithi kanye nokwelashwa okuqondiwe.

Isampula Yomkhiqizo

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C6H12O5
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe
Inombolo ye-CAS	3615-37-0
Ukupakisha	Encane futhi enkulu
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.