I-H-Glu-(OMe)-OMe·I-HCL CAS:23150-65-4

I-H-Glu-(OMe)-OMe·HCl isebenza njengesakhiwo esibalulekile ekuhlanganisweni kwe-peptide, okuvumela ukwakhiwa kwama-peptide anezakhiwo ezilungiselelwe ngenxa yokuba khona kwamaqembu e-methyl ester. Lezi zinguquko zithinta ukusabela kwamakhemikhali kanye nokusebenzisana kwe-hydrophobic kwe-peptide, okwenza kube wusizo ekwakheni ama-peptide anokuvuleka kwe-membrane okuthuthukisiwe noma amakhono athile okukhomba. Ekuthuthukisweni kwemithi, le nhlanganisela ingasetshenziswa ukudala izidakamizwa ezisekelwe ku-peptide ngokuqina okuthuthukisiwe kanye nokutholakala kwezinto eziphilayo, okungenzeka kuholele ekusebenzeni kahle kokwelapha okuthuthukisiwe, ikakhulukazi ngesimo sayo se-HCl. Ngaphezu kwalokho, ocwaningweni lwe-proteomics kanye nolwe-biochemical, i-H-Glu-(OMe)-OMe·HCl ithola izinhlelo zokusebenza ekutadisheni ukusebenzisana kwamaprotheni namaprotheni, ekuphenyeni imisebenzi ye-enzyme, nasekuhloleni amandla okugoqa amaprotheni. Izakhiwo zayo ezihlukile zivumela abacwaningi ukuthi bahlole ubunzima bezinqubo zamaseli kanye nezindlela zezifo, okufaka isandla ekuthuthukisweni kokuqonda impilo kanye ne-pathology. Ukuguquguquka kanye nokuhambisana kwale nhlanganisela nezimo ezahlukahlukene zokuhlola kwenza kube yingxenye ebalulekile yokwembula ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Ekuphetheni, i-H-Glu-(OMe)-OMe·HCl imele ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide anezakhiwo ezithile futhi ihlukanise izindlela eziyisisekelo zezinqubo zezinto eziphilayo, ngaleyo ndlela inikele ekuthuthukisweni kwezokwelapha kanye ne-biotechnology.