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I-2′-O-Methyluridine CAS:2140-76-3 Intengo Yomkhiqizi
I-2′-O-Methyluridine iyi-nucleoside eguquliwe equkethe iqembu le-methyl endaweni engu-2′ yendandatho ye-ribose. Iyisakhiwo esibalulekile ekuhlanganisweni kwama-molecule e-RNA aguquliwe futhi ifundwe ngezakhiwo zayo ezingaba khona zezinto eziphilayo nezemithi. Ezinye zezicelo zayo ezibikiwe zifaka phakathi ukusetshenziswa kwayo ocwaningweni lwe-RNA, njengengxenye ekukhiqizweni kwe-RNA eguquliwe yezicelo zokwelapha nezokusebenza kwe-genomics, kanye nethuluzi ocwaningweni lwesakhiwo nomsebenzi we-RNA.
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I-4-Amino-1-((2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one I-CAS:951-77-9
I-2′-Deoxycytidine iyi-nucleoside eyakhiwe yi-nucleobase cytosine exhunywe ku-sugar deoxyribose. Iyingxenye ebalulekile ye-DNA futhi idlala indima ebalulekile ekugcinweni nasekudluliselweni kolwazi lwezakhi zofuzo ngaphakathi kwezinto eziphilayo.
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I-Cytidine-5′-monophosphate (CMP), i-asidi yamahhala i-CAS:63-37-6
I-Cytidine 5'-monophosphate (CMP) iyi-nucleotide esebenza njengesisekelo sokwakhiwa nokuguqulwa kwe-RNA. Iyingxenye ebalulekile ekwakhiweni kwama-molecule e-RNA futhi ihilelekile ezinqubweni ezifana nokugoba kwe-mRNA kanye ne-metabolism ye-nucleotide. I-CMP isetshenziswa futhi ocwaningweni lwe-biochemical kanye ne-molecular biology lwezinhlelo zokusebenza ezifana nokubhalwa kwe-in vitro kanye nokulebula i-nucleic acid. Indima yayo ku-metabolism ye-RNA kanye nokusetshenziswa kwayo kumasu ahlukahlukene okuhlola kwenza kube ithuluzi elibalulekile ekuqondeni isakhiwo kanye nomsebenzi wama-molecule e-RNA.
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I-IBMX, i-3-isobutyl-1-methylxanthine CAS:28822-58-4
I-3-isobutyl-1-methylxanthine, eyaziwa nangokuthi i-IBMX, iyi-derivative ye-methylxanthine evame ukusetshenziswa ocwaningweni lwesayensi njengesivimbeli esingaqondile sama-cyclic nucleotide phosphodiesterases. Kwaziwa ukuthi ikhulisa amazinga angaphakathi kweseli e-cyclic AMP (cAMP) kanye ne-cyclic GMP (cGMP) ngokuvimbela ukuwohloka kwawo, okungaguqula izindlela ezahlukene zokuthumela izimpawu zamaseli.
Ngaphezu kwezicelo zayo zocwaningo, i-IBMX isetshenziswe kwezinye izindawo zezokwelapha ngenxa yemiphumela yayo ye-bronchodilator kanye ne-vasodilator. Kodwa-ke, ukusetshenziswa kwayo kwezokwelapha kwabantu kulinganiselwe.
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4-Nitrophenyl phosphate disodium salt hexahydrate CAS:4264-83-9
I-4-Nitrophenyl phosphate disodium salt hexahydrate iyinhlanganisela yamakhemikhali evame ukusetshenziswa ocwaningweni lwe-biochemical kanye nemithi. Iwuhlobo lukasawoti lwe-4-nitrophenyl phosphate, equkethe ama-ion amabili e-sodium nama-molecule amanzi ayisithupha. Le nhlanganisela ivame ukusetshenziswa njengesisekelo sokuhlolwa kwe-phosphatase kanye nasekufundweni kwe-enzyme kinetics.
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I-5′-Deoxy-5-fluorocytidine CAS:66335-38-4
I-5′-Deoxy-5-fluorocytidine iyi-analog ye-nucleoside yokwenziwa ephenywayo ngomsebenzi wayo ongaba khona wokulwa namagciwane, ikakhulukazi ngokumelene namagciwane e-RNA njengegciwane le-hepatitis C (HCV) kanye namagciwane e-flavi. Isebenza ngokuphazamisa ukuphindaphindeka kwezinto zofuzo zegciwane, ekugcineni ivimbele ikhono legciwane lokwanda nokusabalala emzimbeni.
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I-Cytidine-5′-triphosphate (CTP), usawoti we-disodium I-CAS:652154-13-7
I-Cytidine-5′-triphosphate (CTP), usawoti we-disodium iyi-triphosphate ye-nucleoside esebenza njengesisekelo sokwakhiwa kwe-RNA. Idlala indima ebalulekile ekusetshenzisweni kwe-metabolism yamaseli futhi ibalulekile ekudlulisweni kolwazi lwezakhi zofuzo kusuka ku-DNA kuya ku-RNA ngesikhathi sokubhalwa. I-CTP isetshenziswa kabanzi ocwaningweni lwe-molecular biology, ikakhulukazi ezifundweni ezihlobene nokwakheka kwe-RNA, ukuphazamiseka kwe-RNA, kanye nezinye izinqubo ezihlobene ne-RNA. Ngaphezu kwalokho, isetshenziswa ekuphenduleni kwe-enzyme, ezifundweni ze-nucleotide metabolism, kanye nanjengesisekelo sokuhlolwa okuhlukahlukene kwe-biochemical. Embonini yezemithi, i-CTP ingaba nezicelo ezingaba khona ekuthuthukisweni kwemithi yokulwa namagciwane kanye neyomdlavuza.
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ITP, inosine 5′-triphosphate trisodium salt CAS:35908-31-7
Usawoti we-Inosine-5′-triphosphate trisodium, ovame ukufushaniswa ngokuthi i-ITP-Na3, uwuhlobo lwe-inosine lwe-triphosphate, i-nucleoside edlala indima ebalulekile ezinqubweni ezahlukene zezinto eziphilayo. Le nhlanganisela iyisimo sikasawoti, okwenza incibilike emanzini futhi ifanele ukusetshenziswa ekuhlolweni kwamakhemikhali kanye ne-enzymatic, kanye nocwaningo lwe-molecular biology. Usawoti we-Inosine-5′-triphosphate trisodium usetshenziselwa ukufunda ukusabela kwe-enzymatic, i-nucleotide interconversion, kanye ne-substrate yama-enzyme athile. Ukusetshenziswa kwawo kudlulela nasezifundweni ze-nucleotide analog kanye nanjengengxenye ekulungiseleleni izingxube ze-nucleotide ezisetshenziswa kumasu e-molecular biology.
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I-5-Bromouracil CAS: 51-20-7 Intengo Yomkhiqizi
I-5-Bromouracil iyi-analog yokwenziwa ye-uracil, eyingxenye ye-RNA. I-5-Bromouracil ingafakwa kuma-nucleic acid futhi ingadala izinguquko ngokungasebenzi kahle kwe-guanine ngesikhathi sokuphindaphinda kwe-DNA. Isetshenziswa njenge-mutagen ocwaningweni lwezakhi zofuzo ukuze kufundwe amazinga okuguqulwa kwezakhi zofuzo kanye nezindlela.
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I-5-Fluoro-2′-deoxyuridine CAS:50-91-9
I-5-Fluoro-2′-deoxyuridine iyi-analog ye-nucleoside yokwenziwa evimbela ukwakheka kwe-DNA. Ihlolisiswe ngezakhiwo zayo ezingaba khona zokulwa namagciwane kanye nokulwa nomdlavuza. Ngaphezu kwalokho, isetshenziswa njengethuluzi lokucwaninga ku-biology yamangqamuzana kanye ne-biochemistry.
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usawoti we-disodium we-Cytidine-5′-triphosphate CAS:36051-68-0
Usawoti we-disodium i-Cytidine-5′-triphosphate (CTP-Na2) uyi-triphosphate ye-nucleoside esebenza njengesisekelo sokwakha ekwakhiweni kwe-RNA. Idlala indima ebalulekile ekusetshenzisweni kwamaseli, isebenza njengesisekelo sama-polymerase e-RNA ekubhalweni nasekusetshenzisweni kwamandla kwe-enzyme ehlukahlukene. I-CTP-Na2 ivame ukusetshenziswa ocwaningweni lwe-biochemical kanye ne-molecular biology njengengxenye yokusabela okubandakanya ukwakheka kwe-RNA, ukuguqulwa, kanye nokulawulwa kwayo. Uhlobo lwayo lwe-disodium salt lukhulisa ukuncibilika kwayo ezixazululweni zamanzi, okwenza kube lula ukusetshenziswa elabhorethri.
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I-Ribonucleic acid evela ku-Baker's Yeast CAS:63231-63-0
I-Ribonucleic acid (i-RNA) evela kumvubelo kaBaker, eyaziwa nangokuthi i-Saccharomyces cerevisiae, ibhekisela kuma-molecule e-RNA akhona kule fungus evamile eneseli elilodwa. Isebenza imisebenzi ehlukahlukene ebalulekile esitokisini, okuhlanganisa ukwakheka kwamaprotheni, umsebenzi we-enzymatic, kanye nokulawulwa kwezakhi zofuzo. I-RNA evela kumvubelo kaBaker iyathakazelisa ososayensi nabacwaningi abafunda i-biology yama-molecular, izakhi zofuzo, kanye nezinqubo zamaseli. Isetshenziswa ezinhlobonhlobo zokuhlola nezifundo ukuze kutholakale ukuqonda ngokuvezwa kwezakhi zofuzo, ukucutshungulwa kwe-RNA, kanye nezinqubo zama-molecule ezisekela imisebenzi yamaseli.
