I-5-Bromouracil CAS: 51-20-7 Intengo Yomkhiqizi

I-5-bromouracil iyi-analog yokwenziwa ye-thymine, ingxenye ye-DNA. Uma ikhona ku-DNA, i-5-bromouracil ingadlula ekushintsheni kwe-tautomeric, okuholela ekungahambelani kahle ne-guanine ngesikhathi sokuphindaphinda kwe-DNA, okungabangela ukuguqulwa kwezakhi zofuzo. Lesi sici senze i-5-bromouracil yaba usizo njenge-mutagen ocwaningweni lwezakhi zofuzo, ikakhulukazi ekutadisheni amazinga okuguqulwa kwezakhi zofuzo kanye nezindlela. Iphinde yasetshenziswa ekuphenyeni isakhiwo kanye nomsebenzi we-nucleic acid, kanye nasezifundweni ezihlobene nokulungiswa kwe-DNA kanye nezinqubo zokuphindaphinda. Ngaphezu kwalokho, i-5-bromouracil isetshenziswe ukutadisha i-mutagenesis kanye nokubonakaliswa kwezakhi zofuzo ezintweni eziphilayo ezahlukahlukene.