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![I-3-FLUORO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE CAS:719268-92-5](https://cdn.globalso.com/xindaobiotech/HSUS81DS80Y35NTEZTU357.png)
I-3-FLUORO-5-(4,4,5,5-TETRAMETHYL-[1,3,2]DIOXABOROLAN-2-YL)PYRIDINE CAS:719268-92-5
3-I-Fluoro-5-(4,4,5,5-tetramethyl-[1,3,2]dioxaborolan-2-yl)pyridine iyinhlanganisela ephilayo equkethe i-boron ebonakala ngokuba khona kwe-athomu ye-fluorine endandatho ye-pyridine kanye ne-dioxaborolane substituent. Lesi sakhiwo esiyingqayizivele sithuthukisa ukusabela kwayo kanye nokuqina, okwenza kube ngumxhumanisi obalulekile ezinhlelweni ezahlukahlukene zokwenziwa. Ukufakwa kwayo ekuphenduleni okuhlanganisiwe, njengokusabela kwe-Suzuki-Miyaura, kuvumela ukwakheka okuphumelelayo kwezibopho ze-carbon-carbon. Njengesakhiwo esiguquguqukayo, le nhlanganisela idlala indima ebalulekile ekuthuthukisweni kwemithi, amakhemikhali ezolimo, kanye nezinto ezithuthukisiwe, igcizelela ukubaluleka kwayo kumakhemikhali wokwenziwa wesimanje.
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1-Bromoadamantane CAS:768-90-1
I-1-Bromoadamantane iyinhlanganisela yezinto eziphilayo eyingxenye yomndeni we-adamantane, ehlukaniswa ngokuba khona kwe-athomu ye-bromine exhunywe ku-carbon yokuqala yesakhiwo se-adamantane. Le nhlanganisela igcina uphawu oluhlukile lwesakhiwo se-adamantane, okufaka isandla ekuzinzeni kwayo kanye nokuziphatha kwayo okuhlukile kwamakhemikhali. I-1-Bromoadamantane isetshenziswa kakhulu ekuhlanganisweni kwezinto eziphilayo kanye ne-chemistry yezokwelapha, isebenza njengesihluthulelo esiyinhloko sokukhiqiza izinto ezahlukahlukene ezitholakalayo. Ukusebenza kwayo namanye amaqembu asebenzayo kuyenza ibe usizo ekuhloleni amakhemikhali amasha anezicelo ezingaba khona zemithi.
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I-6-(4-morpholinyl)-3-pyridinylboronic acid I-CAS:904326-93-8
6-I-(4-Morpholinyl)-3-pyridinylboronic acid iyinhlanganisela equkethe i-boron equkethe iqembu le-morpholine elixhunywe endandatho ye-pyridine endaweni yesithupha kanye neqembu elisebenzayo le-boronic acid. Ifomula yayo yama-molecule yi-C11H14BNO2. Le nhlanganisela ibalulekile ekwakhiweni kwezinto eziphilayo, ikakhulukazi kumakhemikhali ezokwelapha, lapho isebenza khona njengesakhiwo esibalulekile sokuthuthukiswa kwama-molecule asebenzayo. Izici ezihlukile zesakhiwo zinikeza ukusabela okuthile, okuvumela ukuthi uhlanganyele ekusabeleni okubalulekile njenge-Suzuki-Miyaura cross-coupling, okusiza ukwakheka kwezibopho ze-carbon-carbon kuma-compound ayinkimbinkimbi e-organic.
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I-6-(Morpholin-4-yl)pyridine-3-boronic acid i-pinacol ester CAS:485799-04-0
I-6-(Morpholin-4-yl)pyridine-3-boronic acid i-pinacol ester iyinhlanganisela equkethe i-boron ebonakala ngokuba khona kwengxenye ye-morpholine enamathiselwe kwindandatho ye-pyridine endaweni yesithupha kanye ne-pinacol ester ye-boronic acid. Le nhlanganisela iphawuleka ngokusebenza kwayo ekuhlanganiseni izinto eziphilayo, ikakhulukazi ekuthuthukisweni kwemithi kanye namakhemikhali ezolimo. Ifomu le-pinacol ester lithuthukisa ukuzinza kanye nokuncibilika kwe-boronic acid, okwenza kube lula ukusetshenziswa kwayo ekusabeleni kwamakhemikhali ahlukahlukene, okuhlanganisa ukuhlangana kwe-Suzuki-Miyaura. Isakhiwo sayo esiyingqayizivele sivumela ukuhlanganiswa kwama-molecule ayinkimbinkimbi e-organic anemisebenzi eyahlukahlukene yebhayoloji.
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I-3-(DiMethylaMino)phenylboronic Acid Hydrochloride (iqukethe i-Anhydride ehlukahlukene) I-CAS:1256355-23-3
3-(Dimethylamino)phenylboronic acid hydrochloride iyinhlanganisela equkethe i-boron equkethe iqembu le-dimethylamino elixhunywe endandatho ye-phenyl endaweni ye-meta kanye neqembu elisebenzayo le-boronic acid. Ifomu le-hydrochloride lithuthukisa ukuncibilika kwayo emanzini, okwenza ifaneleke ukusetshenziswa okuhlukahlukene. Le nhlanganisela idlala indima ebalulekile ekuhlanganisweni kwezinto eziphilayo, ikakhulukazi kumakhemikhali ezokwelapha, lapho isetshenziswa khona njengesakhiwo esiguquguqukayo sokuthuthukisa ama-molecule asebenzayo ngokwezinto eziphilayo. Ukusebenza kwayo okuyingqayizivele, ikakhulukazi ekuphenduleni kwe-Suzuki-Miyaura okuhlanganisiwe, kwenza kube lula ukwakhiwa kwezakhiwo eziphilayo eziyinkimbinkimbi ezibalulekile kwezemithi kanye nesayensi yezinto zokwakha.
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I-5-Bromo-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronic acid CAS:475102-13-7
5-I-Bromo-1-(tert-butoxycarbonyl)-1H-indol-2-ylboronic acid iyinhlanganisela ekhethekile yezinto eziphilayo evame ukusetshenziswa kumakhemikhali emithi kanye nocwaningo lwezinto eziphilayo zokwenziwa. Le nhlanganisela ine-indole core, ebalulekile ekusebenzeni kwezinto eziphilayo, kanye neqembu elisebenzayo le-boronic acid elisiza ukusabela kokuhlangana kwezinqubo zokuhlanganisa ze-Suzuki. Iqembu le-tert-butoxycarbonyl (Boc) linikeza indlela yokuvikela i-amine ngesikhathi sokwenziwa, okuthuthukisa ukuzinza kwenhlanganisela. Lesi sakhiwo siyenza ibe yindawo ebalulekile ekwakhiweni kwama-molecule ahlukahlukene asebenzayo, kufaka phakathi abantu abangaba khona abazongenela izidakamizwa. Izakhiwo zayo ezihlukile zivumela osokhemisi ukuthi bakwazi ukuyilawula futhi bayihlanganise ezinhlakeni zamakhemikhali ezahlukahlukene.
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I-3-Methoxypyridine-5-boronic acid i-pinacol ester CAS:445264-60-8
3-I-Methoxypyridine-5-boronic acid i-pinacol ester iyinhlanganisela ebalulekile equkethe i-boron esetshenziswa kakhulu ekuhlanganisweni kwezinto eziphilayo. Le nhlanganisela inendandatho ye-pyridine ene-methoxy substituent kanye nengxenye ye-boronic acid evikelwe njenge-pinacol ester. Ifomu le-pinacol ester lithuthukisa ukuzinza kokusebenza kwe-boron, okwenza lifaneleke kakhulu ekwelashweni okuhlukahlukene kokuxhuma, ikakhulukazi ekuhlanganisweni kwe-Suzuki-Miyaura. Isebenza njengesakhiwo esiguquguqukayo sokwenza ama-molecule ayinkimbinkimbi, kufaka phakathi imithi kanye namakhemikhali ezolimo, ngenxa yamandla ayo okwenza kube lula ukwakheka kwesibopho se-carbon-carbon kanye nokuguqulwa okuqhubekayo kokusebenza.
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I-Ethyl 2-bromoheptanoate CAS:5333-88-0
I-Ethyl 2-bromoheptanoate iyi-ester ene-halogenated ebonakala nge-athomu ye-bromine exhunywe ku-carbon yesibili yeketanga le-heptanoate le-carbon eziyisikhombisa, neqembu le-ethyl njengengxenye yotshwala. Le nhlanganisela ingeyesigaba sama-acyl bromides futhi isebenza njenge-intermediate ebalulekile ekuhlanganisweni kwezinto eziphilayo ngenxa yokusabela kwayo okuhlukile. Ukuba khona kwamaqembu okusebenza e-bromo kanye ne-ester kuvumela ukuguqulwa okuhlukahlukene kwamakhemikhali, okwenza kube usizo kumakhemikhali emithi, ukusetshenziswa kwe-agrochemical, kanye nokukhiqizwa kwamakhemikhali akhethekile. Isakhiwo sayo sinegalelo ezimpahleni zayo ezihlukile kanye nokusetshenziswa okuguquguqukayo.
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1,3-Dibromo-2-propanol CAS:96-21-9
I-1,3-Dibromo-2-propanol iyinhlanganisela yezinto eziphilayo ene-halogenated enama-athomu amabili e-bromine anamathele kuma-athomu e-carbon yokuqala neyesithathu yomgogodla we-propanol one-carbon ezintathu. Ukuba khona kweqembu le-hydroxyl (-OH) ku-carbon yesibili kwenza kube utshwala obungena-halogenated. Isakhiwo esiyingqayizivele sale nhlanganisela sinikeza ukusabela kwamakhemikhali okuhlukile kanye nezakhiwo, okwenza kube yindawo ebalulekile ekuhlanganisweni kwezinto eziphilayo. Isetshenziswa kakhulu ekulungiseleleni izinto eziphilayo ezahlukahlukene futhi inezicelo kumakhemikhali ezokwelapha, amakhemikhali ezolimo, kanye nokukhiqizwa kwamakhemikhali akhethekile ngenxa yamandla ayo okuzibandakanya ekuphenduleni kokushintsha kwe-nucleophilic.
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3,3-DIMETHYL-1-BUTANOL CAS:624-95-3
I-3,3-Dimethyl-1-butanol iyi-alcohol ene-branched chain ebonakala ngeqembu le-hydroxyl (-OH) elixhunywe ku-carbon yokuqala ye-butane ye-carbon ezine, enamaqembu amabili e-methyl engeziwe ku-carbon yesithathu. Lesi sakhiwo esiyingqayizivele sinikeza izakhiwo zamakhemikhali ezihlukile, okwenza kube yinto ethakazelisayo kumakhemikhali e-organic kanye nezicelo zezimboni. Yaziwa ngekhono layo lokusebenza njengesinyibilikisi kanye nesiphakathi ekusabeleni okuhlukahlukene kwamakhemikhali. Ukwakheka kwayo kwe-branched kunegalelo ekunciphiseni ukuguquguquka uma kuqhathaniswa ne-linear alcohols, okungaba wusizo ezisetshenzisweni eziningana okuhlanganisa ukwakheka kukaphethiloli kanye namakhemikhali akhethekile.
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I-2-CHLORO-5-FLUORO-3-NITROPYRIDINE CAS:936250-17-8
2-I-Chloro-5-fluoro-3-nitropyridine iyinhlanganisela enuka kamnandi ene-halogen engowomndeni we-pyridine, ebonakala ngokuba khona kwe-chlorine kanye ne-fluorine esikhundleni sesibili nesesihlanu, ngokulandelana, kanye neqembu le-nitro endaweni yesithathu. Le nhlanganisela inefomula yama-molecule i-C5H4ClFNO2 futhi ikhombisa izakhiwo zamakhemikhali ezihlukile ngenxa yokuba khona kwama-athomu amaningi angenawo ama-electronegative. Isebenza njengesixhumi esibalulekile ekuhlanganisweni kwezinto eziphilayo kanye ne-chemistry yemithi, lapho isetshenziswa khona ekuthuthukisweni kwamakhemikhali ahlukahlukene asebenzayo ngokwezinto eziphilayo, ikakhulukazi emikhakheni yamakhemikhali ezolimo kanye ne-chemistry yezokwelapha.
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(4-BOC-AMINOPHENYL)BORONIC ACID CAS:380430-49-9
I-(4-BOC-aminophenyl)boronic acid iyinhlanganisela ebonakala ngeqembu elisebenzayo le-boronic acid elixhunywe ku-4-tert-butyloxycarbonyl (BOC) modified aminophenyl moiety. Le nhlanganisela ithola usizo ekuhlanganisweni kwezinto eziphilayo, ikakhulukazi ekuhlanganyeleni okuhlanganisiwe, indlela eyinhloko yokwakha izibopho ze-carbon-carbon emkhakheni we-chemistry yezokwelapha kanye nesayensi yezinto. Iqembu le-BOC lisebenza njengeqembu elivikela i-amine, lisiza ekuguqulweni okuhlukahlukene ngenkathi livimbela ukusabela okungekuhle. Lapho isuswa ekuvikeleni, ukusebenza kwe-amine kungabamba iqhaza ekuphenduleni okuqhubekayo, okuthuthukisa ukuguquguquka kwe-(4-BOC-aminophenyl)boronic acid njengesisekelo sokwakha ekwakhiweni kwama-molecule ayinkimbinkimbi e-organic. Ukusetshenziswa kwayo ekuthuthukisweni kwemithi kanye nesayensi yezinto ezibonakalayo kugcizelela ukubaluleka kwayo kumakhemikhali wanamuhla.
