I-CHAPS (3--[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate) isihlanzi esivame ukusetshenziswa ku-biochemistry kanye ne-molecular biology.Isihlanzi se-zwitterionic, okusho ukuthi sinokubili iqembu elikhokhiswe kahle nelibi.
I-CHAPS yaziwa ngekhono layo lokunyibilikisa kanye nokusimamisa amaprotheni olwelwesi lwama-membrane, okulwenza lusebenziseke ezinhlotsheni ezihlukahlukene ezifana nokukhipha amaprotheni, ukuhlanzwa, kanye nokuhlukaniswa kwezinhlamvu.Iphazamisa ukusebenzisana kwe-lipid-protein, ivumela amaprotheni e-membrane ukuthi akhishwe esimweni sawo somdabu.
Ngokungafani nezinye izihlanzi, i-CHAPS imnene uma kuqhathaniswa futhi ayiwakhiqizi amaphrotheni amaningi, okwenza kube ukukhetha okuhle kakhulu ekugcineni ukwakheka nokusebenza kwamaprotheni ngesikhathi sokuhlolwa.Kungasiza futhi ukuvimbela ukuhlangana kwamaprotheni.
I-CHAPS ivame ukusetshenziswa kumasu afana ne-SDS-PAGE (i-sodium dodecyl sulfate polyacrylamide gel electrophoresis), i-isoelectric focusing, kanye ne-Western blotting.Ibuye isetshenziswe kaningi ezifundweni ezibandakanya ama-enzyme aboshwe ulwelwesi, ukudluliselwa kwesignali, nokusebenzisana kwamaprotheni-lipid.