2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate CAS:86520-63-0

I-2,3,4,6-Tetra-O-acetyl-α-D-galactopyranosyl 2,2,2-trichloroacetimidate iyinhlanganisela yamakhemikhali evame ukusetshenziswa kumakhemikhali we-carbohydrate kanye nokusabela kwe-glycosylation.Iphuma ku-α-D-galactopyranose, uhlobo lukashukela, lapho amaqembu e-hydroxyl asezindaweni ezingu-2, 3, 4, nezi-6 zendandatho ye-galactopyranose ane-acetylated.Ukwengeza, i-anomeric carbon (C1) yoshukela ivikelwe ngeqembu le-trichloroacetimidate, elenza i-electrophile eqinile ngesikhathi sokusabela kwe-glycosylation.

I-compound ivame ukusetshenziswa njenge-ejenti ye-glycosylating ukwethula izingxenye ze-galactose kuma-molecule ahlukahlukene, njengamaprotheni, ama-peptides, noma ama-molecule amancane.Lokhu kungafezwa ngokuphendula le nhlanganisela nge-nucleophile (isb, amaqembu e-hydroxyl ku-molecule eqondiwe) ngaphansi kwezimo ezifanele.Iqembu le-trichloroacetimidate lenza kube lula ukunamathiselwa kwe-galactose moiety ku-molecule eqondiwe, okuholela ekwakhekeni kwebhondi ye-glycosidic.

Lesi sakhi sivame ukusetshenziswa ekuhlanganiseni ama-glycoconjugates, glycopeptides, nama-glycolipids.Inikeza indlela eguquguqukayo nephumelelayo yokushintsha ama-molecule ngezinsalela ze-galactose, ezingaba usizo emikhakheni eyahlukene, okuhlanganisa izifundo zebhayoloji, izinhlelo zokulethwa kwezidakamizwa, noma ukuthuthukiswa komgomo.

Oda noma Cela I-Quote

Imininingwane Yomkhiqizo

Omaka bomkhiqizo

Isicelo kanye Nomphumela

I-Glycosylation: I-compound isabela nama-molecule ahlukahlukene amukelayo aqukethe amaqembu e-hydroxyl, njenge-alcohol noma ama-amines, ukuze kwakheke amabhondi e-glycosidic.Lokhu kuvumela ukwethulwa kwe-galactose ku-molecule eyamukelayo, okuholela ekwakhekeni kwama-glyconjugates, glycopeptides, noma glycolipids.

Ucwaningo lwe-biochemical and biological: Inhlanganisela isiza abacwaningi ukuthi bafunde imisebenzi yebhayoloji kanye nokusebenzisana kwama-molecule aqukethe i-galactose.Ngokukhetha ngokunamathisela i-galactose kumaprotheni, ama-peptide, noma amanye ama-biomolecules, abacwaningi bangaphenya izindima zabo ezinqubweni zamaselula, ukusebenzisana kwe-receptor-ligand, nezindlela zezifo.

Amasistimu okulethwa kwezidakamizwa: Inhlanganisela ingasetshenziswa ukuguqula ama-molecule ezidakamizwa ngezinsalela ze-galactose, kube lula ukulethwa kwezidakamizwa okuhlosiwe kumathishu noma amaseli athile.I-Galactose ingasebenza njenge-ligand eqondisayo, ibona ama-receptors athile avezwa ebusweni bamaseli, ikakhulukazi ama-hepatocyte.Ngokunamathisela i-galactose ezidakamizweni, abacwaningi bangathuthukisa ukukhetha kwabo kanye nempumelelo ekwelashweni okuhlosiwe.

Ukuthuthukiswa komgomo: Ama-molecule aqukethe i-galactose adlala indima ebalulekile ekuphenduleni amasosha omzimba, njengoba abonwa ama-lectins akhona kumaseli omzimba.Ngokuhlanganisa ama-antigen nezinhlayiya ze-galactose besebenzisa lesi sithako, abacwaningi bangathuthukisa ukuphendula kwamasosha omzimba futhi bakhe imithi yokugoma esebenza ngempumelelo kakhudlwana.

I-Chemical synthesis: Inhlanganisela ingasetshenziswa kuma-chemical syntheses ahlukahlukene lapho kudingeka khona ukuguqulwa kwe-galactose.Lokhu kuhlanganisa ukulungiswa kwezakhiwo eziyinkimbinkimbi ze-carbohydrate, i-oligosaccharides, noma i-glycomimetics, engasetshenziswa ngokuqhubekayo kumakhemikhali okwelapha noma njengamathuluzi okucwaninga.

Isampula Lomkhiqizo

Ukupakishwa komkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	I-C16H20Cl3NO10
Isivivinyo	99%
Ukubukeka	Impushana emhlophe
Inombolo ye-CAS.	86520-63-0
Ukupakisha	Ezincane nezinkulu
I-Shelf Life	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	ISO.