1,2,3,4,6-Penta-O-acetyl-D-mannopyranose CAS:25941-03-1

I-1,2,3,4,6-Penta-O-acetyl-D-mannopyranose isetshenziswa ngokuyinhloko njengesandulela ekuhlanganisweni kwe-Glycosylated compounds.I-Glycosylation isho inqubo yokunamathisela i-molecule kashukela, njenge-mannose, kwenye i-molecule (isb., amaprotheni, ama-peptide, izidakamizwa) ukuze kuguqulwe izakhiwo zazo noma ukuthuthukisa imisebenzi yazo.Lolu hlobo lwe-acetylated lwe-D-mannose lungasetshenziswa ukwethula izingxenye ze-mannose kuma-molecule ahlukahlukene ngokusabela kwamakhemikhali.

Esinye sezicelo ezibalulekile ze-1,2,3,4,6-Penta-O-acetyl-D-mannopyranose sisekuhlanganisweni kwemithi yokugoma ye-glicoconjugate.Ngokuxhumanisa i-mannose ene-acetylated nephrotheni ethwalayo, i-glyccoconjugate ewumphumela ilingisa ukwakheka kwama-antigen angaphezulu amagciwane.Lokhu kusiza ukuvuselela ukusabela okuqondile kokuzivikela komzimba, okuholela ekukhiqizeni amasosha omzimba ngokumelene nalawo magciwane.

Ngaphezu kwalokho, le nhlanganisela ingasetshenziswa futhi ekuhlanganiseni ama-glycosides nama-oligosaccharides, anezicelo ezingase zibe njengama-ejenti okwelapha, ama-enzyme inhibitors, nezinhlelo zokulethwa kwezidakamizwa.Ngokukhohlisa amaqembu e-acetyl ku-molecule ye-mannose, abacwaningi bangashintsha izakhiwo nokusebenzelana kwalezi zinhlanganisela, zizenze zikhethe futhi ziphumelele.