1,2,3,4,6-Penta-O-acetyl-D-mannopyranose CAS:25941-03-1

I-1,2,3,4,6-Penta-O-acetyl-D-mannopyranose isetshenziswa kakhulu njengesandulela ekwakhiweni kwamakhemikhali e-Glycosylated. I-Glycosylation ibhekisela enkambisweni yokunamathisela i-molecule kashukela, njenge-mannose, kwenye i-molecule (isb., amaprotheni, ama-peptide, izidakamizwa) ukushintsha izakhiwo zawo noma ukuthuthukisa imisebenzi yawo. Lolu hlobo lwe-D-mannose olune-acetylated lungasetshenziswa ukwethula izingxenye ze-mannose kuma-molecule ahlukahlukene ngokusebenzisa ukusabela kwamakhemikhali.

Enye yezindlela ezibalulekile zokusebenzisa i-1,2,3,4,6-Penta-O-acetyl-D-mannopyranose ukwenziwa kwemithi yokugomela i-glycoconjugate. Ngokuxhumanisa i-acetylated mannose neprotheni ethwalayo, i-glycoconjugate ephumayo ilingisa isakhiwo sama-antigen angaphezulu athile ezinto eziphilayo. Lokhu kusiza ekuvuseleleni impendulo ethile yomzimba, okuholela ekukhiqizweni kwama-antibodies ngokumelene nalezo zinto eziphilayo.

Ngaphezu kwalokho, le nhlanganisela ingasetshenziswa futhi ekwakhiweni kwama-glycoside nama-oligosaccharides, anezicelo ezingaba khona njengezinto zokwelapha, izithiyo zama-enzyme, kanye nezinhlelo zokulethwa kwemithi. Ngokusebenzisa amaqembu e-acetyl ku-molecule ye-mannose, abacwaningi bangashintsha izakhiwo kanye nokusebenzisana kwala ma-compound, okwenza akhetheke futhi asebenze kahle.