I-Z-MeVal-OH CAS:42417-65-2

Lo mkhiqizo usetshenziswa kakhulu abacwaningi nezinkampani zemithi ukuze kuhlanganiswe ama-peptide aqukethe izinsalela ze-N-methylvaline. I-N-methylvaline yaziwa ngekhono layo lokuthuthukisa ukuzinza kokwakheka kanye nokuvuleka kwe-membrane yama-peptide, okwenza kube yisisekelo esibalulekile ekuthuthukisweni kwemithi nemithi yokwelapha esekelwe kuma-peptide. I-Z-MeVal-OH ihlanzekile kakhulu futhi iyahambisana nezinye izinto ezisetshenziswayo, okwenza kube ukukhetha okuthembekile kwamaphrojekthi okwenziwa kwama-peptide. I-Z-MeVal-OH iyithuluzi eliguquguqukayo labacwaningi emikhakheni ye-biochemistry, i-pharmacology, kanye nokutholwa kwemithi. Ukuqina kwayo, ubumsulwa, kanye nokuhambisana kwayo kwenza kube yingxenye ebalulekile ekuhlanganisweni kwama-peptide aqukethe i-N-methylvaline, anezicelo ezingaba khona ekuthuthukisweni kwemithi, ocwaningweni lwezinto eziphilayo, kanye nokungenelela kokwelapha. Ngokufaka i-Z-MeVal-OH kuchungechunge lwama-peptide, abacwaningi bangakha ama-compound amasha anezakhiwo ze-bioactivity ezithuthukisiwe kanye ne-pharmacokinetic, bathuthukise insimu yokutholwa kwemithi esekelwe kuma-peptide.