I-VALINOMYCIN CAS:2001-95-8 Intengo Yomkhiqizi

I-Valinomycin iyi-antibiotic yemvelo ye-cyclic peptide ekhiqizwa ngokuyinhloko yizinhlobo ezithile zamagciwane e-Streptomyces. Yakhiwe umjikelezo wama-amino acid ashintshanayo e-D- kanye ne-L-amino, ene-motif ye-cyclic depsipeptide ephakathi. I-Valinomycin yaziwa kakhulu ngokuhambisana kwayo okuphezulu kwama-cation e-monovalent, ikakhulukazi ama-ion e-potassium (K+).

Ngenxa yekhono layo lokubopha nokuthutha ama-ion e-potassium ngokukhetha kuwo wonke ama-membrane ezinto eziphilayo, i-valinomycin ithole izinhlelo zokusebenza ezahlukahlukene ocwaningweni lwesayensi kanye ne-biotechnology. Isetshenziswa kabanzi njenge-ionophore kuma-electrode akhetha ama-ion ukuze kulinganiswe amazinga e-potassium kumasampula ezinto eziphilayo. Ikhono eliyingqayizivele le-Valinomycin lokuthutha ama-ion e-potassium ngokukhetha liphinde lenze kube usizo ezifundweni zokuthuthwa kwama-ion kanye nekhono le-membrane kumaseli.

Oda noma Cela Isilinganiso

Imininingwane Yomkhiqizo

Amathegi Omkhiqizo

Ukusetshenziswa kanye Nomphumela

I-Valinomycin isebenza ngokuyinhloko njenge-ionophore, okusho ukuthi yenza kube lula ukuthuthwa kwama-ion athile kuwo wonke ama-membrane esisele. Umphumela wayo ophawuleka kakhulu ukuhambisana kwayo okunamandla nama-ion e-potassium (K+). I-Valinomycin yakha inhlanganisela enama-ion e-K+, okwenza ikhetheke kakhulu ekuthuthweni kwayo.

Enye yezindlela eziyinhloko zokusebenzisa i-valinomycin njenge-ionophore kuma-electrode akhetha ama-ion ukuze kulinganiswe amazinga e-potassium kumasampula ebhayoloji. Lawa ma-electrode asebenzisa ikhono le-valinomycin lokubopha nokuthutha ama-ion e-K+ ngokukhetha, okwenza kube nokulinganiswa okunembile nokuzwela kwama-ion e-potassium.

Ikhono le-Valinomycin lokuthutha ama-ion e-potassium liphinde lenze libe usizo ocwaningweni oluhlobene nokuthuthwa kwama-ion kanye nekhono le-membrane emaseli. Lisetshenziselwa ukutadisha indima yeziteshi ze-ion, amandla e-membrane, kanye ne-ion gradients ezinqubweni ezahlukene zezinto eziphilayo.

Ngaphezu kwalokho, i-valinomycin iye yaphenywa ngezinhlelo zayo zokwelapha ezingaba khona. Ibonise imiphumela ethembisayo njenge-ejenti yokulwa nomdlavuza ezinhlotsheni ezithile zomdlavuza. I-Valinomycin ibangela i-apoptosis (ukufa kwamangqamuzana) emaseli omdlavuza ngokuphazamisa amandla awo e-mitochondrial membrane.

Ukupakisha Umkhiqizo:

Ulwazi Olwengeziwe:

Ukwakheka	C54H90N6O18
Ukuhlolwa	99%
Ukubukeka	Impuphu emhlophe
Inombolo ye-CAS	2001-95-8
Ukupakisha	Encane futhi enkulu
Impilo Yeshelufu	iminyaka engu-2
Isitoreji	Gcina endaweni epholile neyomile
Isitifiketi	I-ISO.