I-Sitagliptin Phosphate CAS: 654671-78-0 Umhlinzeki Womkhiqizi

I-Sitagliptin Phosphate iyi-trizolopyrazine dipeptidyl peptidase IV inhibitor. I-Sitagliptin isanda kuvunyelwa ekwelapheni isifo sikashukela sohlobo lwesibili. I-Sitagliptin phosphate iyi-dipeptidyl peptidase Ⅳ(DDP-4) inhibitor class yemithi eyenziwe yinkampani yaseJalimane i-Merck futhi okokuqala yathola imvume ye-US Food and Drug Administration yokwelapha isifo sikashukela sohlobo lwesibili, iyisidakamizwa esisha sokwelapha isifo sikashukela, ingathuthukisa ikhono lomzimba lokunciphisa amazinga aphezulu kashukela egazini, kanye nokwanda kwe-incretin okwenzeka ngokwemvelo ngokuvimbela umsebenzi wale enzyme, kufaka phakathi amazinga e-glucagon-like peptide 1 kanye ne-glucose-dependent insulinotropic peptide, ngaleyo ndlela ibangele ukuthi ama-pancreas athuthukise ukukhiqizwa kwe-insulin futhi amise ukukhiqizwa kwe-glucose esibindini, futhi ekugcineni kunciphise umphumela wezokwelapha wokuhlushwa kwe-glucose egazini.