I-Sitagliptin Phosphate CAS:654671-78-0 Umkhiqizi Supplier

I-Sitagliptin Phosphate iyi-trizolopyrazine dipeptidyl peptidase IV inhibitor.I-Sitagliptin isanda kugunyazwa ukwelapha uhlobo lwesifo sikashukela sohlobo lwesibili. I-Sitagliptin phosphate iyikilasi le-dipeptidyl peptidase Ⅳ(DDP-4) inhibitor yekilasi lemithi ethuthukiswe inkampani yaseJalimane i-Merck futhi yaqale yathola imvume ye-US Food and Drug Administration yokwelapha uhlobo 2. isifo sikashukela, isidakamizwa esisha se-antidiabetic, singathuthukisa ikhono lomzimba ngokwalo lokunciphisa amazinga kashukela aphezulu egazini, kanye nokwanda okulinganiselwe okwenzeka ngokwemvelo kwe-incretin ngokuvimbela umsebenzi wale enzyme, okuhlanganisa amazinga e-glucagon-like peptide 1 kanye ne-insulinotropic encike ku-glucose. i-peptide, ngaleyo ndlela ivuse ama-pancreas ukuthi athuthukise ukukhiqizwa kwe-insulin futhi amise ukukhiqizwa kwe-glucose esibindini, futhi ekugcineni anciphise umphumela womtholampilo wokuhlushwa kweglucose yegazi.