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2,2-DIISOAMYL-1,3-PROPANEDIOL CAS:403519-64-2
I-2,2-Diisoamyl-1,3-propanediol iyinhlanganisela yezinto eziphilayo ebonakala ngomgogodla wayo we-propanediol enamaqembu amabili e-isoamyl anamathele ku-carbon yesibili. Iwuketshezi olungenambala, oluqinile olwaziwa ngezakhiwo zalo ezifana ne-glyceryl. Le nhlanganisela ithole ukunakwa emikhakheni eyahlukahlukene ngenxa yesakhiwo sayo esiyingqayizivele sama-molecule kanye nezicelo ezingaba khona ekwakhiweni kwamakhemikhali kanye nesayensi yezinto.
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I-METHYL OXALYL CHLORIDE CAS:5781-53-3
I-Methyl oxalyl chloride iyinhlanganisela eyinhloko yephunga ebonakala ngokuba khona kwamaqembu amabili e-carbonyl kanye ne-athomu ye-chlorine exhunywe eqenjini le-methyl. Ngefomula yamakhemikhali i-C4H3ClO3, le nhlanganisela isebenza njengomxhumanisi obalulekile ekuhlanganisweni kwezinto eziphilayo, ikakhulukazi ekulungiseleleni imithi ehlukahlukene kanye namakhemikhali ezolimo. Ukusebenza kwayo kuvela ekubeni khona kokubili imisebenzi ye-oxalyl kanye ne-chlorine, evumela ukuthi ihlanganyele ekuguqulweni kwamakhemikhali okuhlukahlukene. Ucwaningo nge-methyl oxalyl chloride lugqamise ukubaluleka kwayo ekwakhiweni kwama-molecule ayinkimbinkimbi, kufaka phakathi ama-heterocycle abalulekile kanye nezinye izinto eziphilayo ezisebenzayo.
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I-Ethyl oxalyl monochloride CAS:4755-77-5
I-ethyl oxalyl monochloride iyinhlanganisela ebalulekile yezinto eziphilayo ebonakala ngeqembu le-ethyl elixhunywe engxenyeni ye-oxalyl, enamaqembu amabili e-carbonyl kanye ne-athomu eyodwa ye-chlorine. Ngefomula yama-molecule i-C5H7ClO3, le nhlanganisela yaziwa kabanzi njenge-intermediate ebalulekile ekuhlanganisweni kwezinto eziphilayo, ikakhulukazi embonini yezokwelapha kanye ne-agrochemical. Ukusebenza kwayo okuyingqayizivele kuvela kokubili ekusebenzeni kwayo kwe-oxalyl kanye ne-chlorinated, okuvumela ukuthi ihlanganyele ekuguqulweni okuhlukahlukene kwamakhemikhali. Abacwaningi bahlole i-ethyl oxalyl monochloride ngezinhlelo zayo ezingaba khona ekudaleni ama-molecule ayinkimbinkimbi anemisebenzi eyahlukahlukene yezinto eziphilayo.
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I-DL-4-Chlorophenylglycine CAS:6212-33-5
I-DL-4-Chlorophenylglycine iyinhlanganisela yamakhemikhali ethole isithakazelo esikhulu emikhakheni yekhemistri yezokwelapha kanye ne-pharmacology. Njenge-glycine derivative, ineqembu le-chlorophenyl, elithuthukisa izakhiwo zalo zokubopha kanye nomsebenzi webhayoloji. Le nhlanganisela iye yacwaningwa ngezinhlelo zayo ezingaba khona ekwelapheni izifo ezahlukahlukene zezinzwa, ikakhulukazi ngokuguqula ama-receptor e-glutamate. Isakhiwo esiyingqayizivele se-DL-4-Chlorophenylglycine siphinde siyivumele ukuthi isebenze njengomphikisi noma i-agonist kuye ngendawo yayo, okwenza ibe yi-candidate eguquguqukayo yocwaningo ngemithi yokwelapha ye-neuropharmacological. Ukuhlanganiswa kwayo kanye nokuhlukaniswa kwayo kuyaqhubeka nokuba yizindawo zophenyo olusebenzayo.
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I-DRONEDARONE HYDROCHLORIDE CAS:141625-93-6
I-Dronedarone hydrochloride iwumuthi olwa nokushaya kwenhliziyo osetshenziswa kakhulu ekuphatheni i-atrial fibrillation kanye ne-atrial flutter. Njengoba isuselwa ku-amiodarone, yathuthukiswa ukuze inikeze izinzuzo ezifanayo zokwelapha ngenkathi inciphisa eminye yemiphumela emibi ehlotshaniswa ne-amiodarone, ikakhulukazi ubuthi bayo be-thyroid kanye namaphaphu. I-Dronedarone isebenza ngokwandisa amandla okusebenza kanye nesikhathi sokungaguquki ezicutshini zenhliziyo, iqinise isigqi senhliziyo, futhi inciphise ingozi yokulaliswa esibhedlela ngenxa yezehlakalo zenhliziyo. Ivunyelwe ukusetshenziswa emitholampilo emazweni ahlukahlukene, i-dronedarone imelela intuthuko ebalulekile ekuphathweni kwemithi ye-atrial arrhythmias.
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i-valproic acid CAS:99-66-1
I-Valproic acid, eyaziwa nangokuthi i-2-propylpentanoic acid, iwumuthi osetshenziswa kabanzi wokulwa nokuxhuzula kanye nowokuzinzisa imizwa oqashelwa kakhulu ekwelapheni isifo sokuwa kanye nesifo sokuphazamiseka kwengqondo. Yatholakala ngawo-1960, isebenza ngokwandisa amazinga e-gamma-aminobutyric acid (GABA) ebuchosheni, i-neurotransmitter ebalulekile esiza ukulawula ukujabula kwemizwa. I-Valproic acid ithole ukuqashelwa hhayi nje kuphela ngokusebenza kwayo kahle ekuphatheni ukuxhuzula kodwa futhi nangendima yayo ekuvimbeleni i-migraines kanye nokwelapha izimo ezithile zengqondo. Iphrofayili yayo enhle yezokwelapha iyenza ibe yinto ebalulekile yokwelapha ku-neurology kanye ne-psychiatry.
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I-Sodium Valproate CAS:1069-66-5
I-Sodium valproate, usawoti we-sodium we-valproic acid, umuthi oqeda ukuxhuzula kanye nowokuzinzisa imizwa osetshenziswa kakhulu ekwelapheni isifo sokuwa kanye nesifo sokuphazamiseka kwengqondo. Isebenza ngokwandisa amazinga e-gamma-aminobutyric acid (GABA) ebuchosheni, i-neurotransmitter edlala indima ebalulekile ekunciphiseni ukujabula kwemizwa. Yavunywa ngasekupheleni kwekhulu lama-20, i-sodium valproate yaziwa ngokusebenza kwayo kuzo zonke izinhlobo zokuxhuzula futhi isetshenziswa nasekuvimbeleni i-migraine. Iphrofayili yayo enhle yezokwelapha yenze kwaba inketho ebalulekile yokwelapha ku-neurology kanye ne-psychiatry.
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I-ETHYL 5-AMINOBENZOFURAN-2-CARBOXYLATE CAS:174775-48-5
I-Ethyl 5-aminobenzofuran-2-carboxylate iyinhlanganisela yamakhemikhali eyingxenye yezinhlobo ze-benzofuran, ezibalulekile kumakhemikhali ezokwelapha ngenxa yemisebenzi yazo eminingi yebhayoloji. Le nhlanganisela ineqembu elisebenzayo le-ethyl ester kanye nokufakwa esikhundleni kwe-amino endandatho ye-benzofuran, okwenza kube yisisekelo sokwakha esiguquguqukayo sokwenziwa kwama-molecule asebenzayo. I-Ethyl 5-aminobenzofuran-2-carboxylate ithole ukunakwa ocwaningweni lwezokwelapha ngezicelo zayo ezingaba khona ekuthuthukiseni ama-ejenti amasha okwelapha, ikakhulukazi ezindaweni ezifana nokwelashwa okulwa nokuvuvukala, ukudambisa ubuhlungu, noma ama-antimicrobial, ngenxa yezakhiwo ezihlukile zesakhiwo ezinikezwa yi-scaffold ye-benzofuran.
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I-Diethyl benzylmalonate CAS:607-81-8
I-Diethyl benzylmalonate iyinhlanganisela ebalulekile yezinto eziphilayo esetshenziswa kakhulu kumakhemikhali okwenziwa, ikakhulukazi ekulungiseleleni imithi ehlukahlukene kanye namakhemikhali ezolimo. Le nhlanganisela ye-malonic acid inezinhlobo ezimbili ze-ethyl ester kanye ne-benzyl substituent, ethuthukisa ukusabela kwayo ekuphenduleni kokushintsha kwe-nucleophilic. I-Diethyl benzylmalonate isebenza njengesakhiwo esiguquguqukayo ekwakhiweni kwama-molecule asebenzayo ngokwezinto eziphilayo, kufaka phakathi izinto ezibalulekile ekuthuthukisweni kwemithi. Isakhiwo sayo esiyingqayizivele kanye nezakhiwo zayo zokusebenza kuyenza ibe yinkimbinkimbi ebalulekile kumakhemikhali okwelapha, okuvumela osokhemisi ukuthi bahlole izindlela ezahlukahlukene zokwenziwa zokuthuthukisa izindlela zokwelapha ezintsha.
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I-Indazole CAS:271-44-3
I-Indazole iyinhlanganisela enuka kamnandi enama-bicyclic equkethe indandatho ye-pyrazole enamalungu amahlanu ehlanganiswe nendandatho ye-benzene enamalungu ayisithupha. Lesi sakhiwo se-heterocyclic saziwa ngemisebenzi yaso ehlukahlukene yezinto eziphilayo kanye nokusetshenziswa okungenzeka kumakhemikhali ezokwelapha. I-Indazole kanye nezinto eziphuma kuyo zidonsele ukunaka okukhulu ngenxa yokubandakanyeka kwazo ezicini ezahlukahlukene zezokwelapha, njengemiphumela yokulwa nokuvuvukala, yokulwa nomdlavuza, kanye ne-antimicrobial. Le nhlanganisela isebenza njengesikafu esibalulekile ekuthuthukisweni kwemithi, ikakhulukazi ekwakhiweni kwezindlela zokwelapha ezintsha ezihlose izifo eziningi. Ucwaningo oluqhubekayo luyaqhubeka nokuhlola izindlela zokwenziwa kanye nemiphumela yezinto eziphilayo ehlobene ne-indazole.
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I-ETHYL 5-NITROBENZOURAN-2-CARBOXYLATE CAS:69604-00-8
I-Ethyl 5-nitrobenzofuran-2-carboxylate iyinhlanganisela ebalulekile emkhakheni we-organic chemistry, ikakhulukazi ngaphakathi komkhakha we-heterocyclic compounds. Njenge-nitro-substituted benzofuran derivative, ikhombisa izakhiwo zamakhemikhali ezihlukile kanye nemisebenzi yezinto eziphilayo ezenza kube yinto ekhangayo yocwaningo lwezokwelapha. Ukuba khona kweqembu le-nitro kuthuthukisa ukusabela kwayo, okuvumela ukusetshenziswa okungenzeka ekwakhiweni kwemithi emisha. I-Ethyl 5-nitrobenzofuran-2-carboxylate idonsele ukunaka ngokusetshenziswa kwayo okungenzeka ekuthuthukiseni ama-anti-inflammatory, antimicrobial, kanye nama-anticancer agents, igcizelela ukubaluleka kwayo ekuthuthukisweni kwamasu okuthola i-chemistry yezokwelapha kanye nemithi.
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4-Bromophenylacetone CAS: 6186-22-7
I-4-Bromophenylacetone iyi-aromatic ketone ebonakala nge-bromine esikhundleni se-phenyl ring, kanye neqembu elisebenzayo le-acetone. Le nhlanganisela idonsele ukunaka ekuhlanganisweni kwezinto eziphilayo ngenxa yokuguquguquka kwayo njengesisekelo sokwakha ama-molecule ayinkimbinkimbi kakhulu, okuhlanganisa nemithi kanye namakhemikhali ezolimo. Ukuba khona kwe-athomu ye-bromine kuthuthukisa isimo sayo se-electrophilic, okwenza kube lula ukusabela okuhlukahlukene ezindleleni zokwenziwa. Ngaphezu kwalokho, i-4-bromophenylacetone ibonise imisebenzi engaba khona yezinto eziphilayo, okwenza kube yinto ethakazelisayo kumakhemikhali ezokwelapha ukuze kuhlolwe futhi kusetshenziswe ekutholakaleni kwezidakamizwa.
