Umhlinzeki Womkhiqizi we-Olmesartan Medoxomil CAS:144689-63-4

I-Olmesartan medoxomil iyi-angiotensin II receptor antagonist esetshenziselwa ukwelapha umfutho wegazi ophakeme. I-Olmesartan isebenza ngokuvimbela ukubopha kwe-angiotensin II kuma-receptor e-AT1 emisipheni yemithambo yegazi. Ngokuvimba ukubopha esikhundleni sokwenziwa kwe-angiotensin II, i-olmesartan ivimbela impendulo engalungile yokulawula ekukhiqizweni kwe-renin. I-Olmesartan medoxomil iyisidakamizwa esisekela ukukhishwa kwe-metabolite esebenzayo, i-olmesartan. I-Olmesartan inezindlela ezimbili zokususa, cishe ama-60% asuswa yisibindi kanti okusele kukhishwa yizinso. Ezimweni zokusebenza kwezinso okungasebenzi kahle noma kwesibindi, indlela ehlukile yokukhipha ingabuyisela leyo ethintekile.