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I-Ziconotide CAS:107452-89-1
I-Ziconotide iyisivimbeli se-calcium channel esithathwe ezingxenyeni ezitholakala ebuchosheni beminenke yasolwandle. Inciphisa ukudluliselwa kobuhlungu ngokuvimbela imigudu ye-calcium kuma-neurons futhi isetshenziswa kabanzi emkhakheni wezokwelapha i-analgesia.
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I-DECAPEPTIDE-4 CAS:72957-37-0
I-DECAPEPTIDE-4, eyaziwa nangokuthi i-Acetyl Decapeptide-3, iyi-peptide yokwenziwa esetshenziswa ekwakhiweni kokunakekelwa kwesikhumba ukuqondisa izimpawu ezahlukahlukene zokuguga. Le peptide yenzelwe ukusekela izinqubo zokuvuselela isikhumba nokukhuthaza isikhumba esisesincane ngokubhekana nezinkinga ezifana nemigqa emincane, imibimbi, kanye nokulahlekelwa ukunwebeka. Iyisithako esivame ukufakwa emikhiqizweni yokunakekelwa kwesikhumba elwa nokuguga ngenxa yezakhiwo zayo ezingaba khona zokuvuselela isikhumba.
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I-DIPEPTIDE-1 CAS:72957-37-0
I-DIPEPTIDE-1, eyaziwa nangokuthi i-Acetyl-Dipeptide-1, iyi-peptide yokwenziwa esetshenziswa kabanzi embonini yezimonyo ngenxa yezakhiwo zayo zokuthuthukisa isikhumba. Le dipeptide yenzelwe ukubhekana nezinkinga ezahlukahlukene zesikhumba, ikakhulukazi lezo ezihlobene nokuguga. Kukholakala ukuthi ikhuthaza ukumuncwa kwesikhumba, ithuthukise ukunwebeka, futhi isekele ukubukeka kwesikhumba sonke, inegalelo ekwakhiweni kwesikhumba okusemusha nokugqamile.
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I-Melanotan ll CAS:121062-08-6
I-Melanotan II iyi-peptide yokwenziwa elingisa isenzo se-hormone evuselela i-melanocyte (MSH) yemvelo. Yaziwa kakhulu ngekhono layo lokukhuthaza ukukhiqizwa kwe-melanin esikhumbeni, okuholela ekushiseni isikhumba. Yakhelwe ukusetshenziswa okungenzeka ekwelapheni izimo zesikhumba ezifana ne-vitiligo nokunciphisa ingozi yomdlavuza wesikhumba, ithole ukuthandwa embonini yezimonyo njenge-agent yokushisisa isikhumba.
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I-Melanotan l CAS:75921-69-6
I-Melanotan I, i-peptide yokwenziwa, yenzelwe ukuphindaphinda isenzo se-melanocyte-stimulating hormone (MSH). Isebenza ngokuyinhloko ngokuvuselela ukukhiqizwa kwe-melanin esikhumbeni, okufaka isandla ekushintsheni kombala okufana ne-tan. Ekuqaleni yaklanywa ukuze isetshenziswe ekwelapheni, ihlose ukubhekana nezimo ezifana ne-vitiligo nokunikeza izinzuzo zokuvikela emisebeni ye-UV.
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I-Mastoparan CAS:72093-21-1
I-Mastoparan iyi-peptide toxin etholakala ebuthi be-wasp, eyaziwa ngekhono layo lokuphazamisa ulwelwesi lwamaseli. Isebenzisana ne-lipid bilayers futhi ingathonya imisebenzi yamaseli, okwenza ibe yindaba ethakazelisayo ocwaningweni lwezinto eziphilayo.
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I-Oligopeptide-10 CAS:466691-40-7
I-Oligopeptide-10 iyi-peptide encane eyakhiwe uchungechunge olufushane lwama-amino acid. Ekunakekelweni kwesikhumba, i-Oligopeptide-10 ivame ukusetshenziswa ngenxa yekhono layo lokusekela impilo yesikhumba nokuvuselelwa.
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I-Semaglutide CAS:910463-68-2
I-Semaglutide iyi-peptide-1 (GLP-1) receptor agonist esetshenziswa ekwelapheni isifo sikashukela sohlobo 2. Ilingisa isenzo se-GLP-1, esikhuthaza ukukhishwa kwe-insulin ekuphenduleni ukudla futhi sivimbele ukukhishwa kwe-glucagon kumaseli e-pancreatic alpha.
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I-PNC-27 peptide CAS:1181365-35-4
I-peptide ye-PNC-27 iyi-ejenti entsha yokulwa nomdlavuza eyenzelwe ukuhlasela nokubhubhisa amangqamuzana omdlavuza ngokuphazamisa ulwelwesi lwawo lwamaseli, okuholela ku-apoptosis (ukufa kwamaseli okuhleliwe) ngaphandle kokulimaza amangqamuzana anempilo.
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I-Etelcalcetide CAS:1262780-97-1
I-Etelcalcetide iyi-ejenti ye-calcimimetic esetshenziselwa ukwelapha i-hyperparathyroidism yesibili ezigulini ezinesifo sezinso esingamahlalakhona lapho zihlanzwa nge-hemodialysis. Isebenza ngokulingisa isenzo se-calcium ku-receptor ezwa i-calcium ku-parathyroid gland, ngaleyo ndlela inciphise ukukhiqizwa kwe-parathyroid hormone (PTH).
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I-Pexiganan CAS:147664-63-9
I-Pexiganan iyi-analog yokwenziwa ye-magainin, i-peptide yemvelo yokulwa namagciwane etholakala ekukhiqizweni kwesikhumba sexoxo. Ibonisa umsebenzi onamandla wokulwa namagciwane ngokumelene nezinhlobo eziningi zamagciwane, okwenza kube yikhambi elithembisayo lokusetshenziswa kwezokwelapha.
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I-Humanin CAS:330936-69-1
I-Humanin iyi-peptide engama-amino acid angu-24 ebhalwe yi-genome ye-mitochondrial, eyaziwa ngezakhiwo zayo zokuvikela izinzwa kanye nokuvikela i-cytoprotective. Idlala indima ebalulekile ekusindeni kwamaseli futhi ihilelekile ekulawulweni kwezinqubo ezahlukahlukene zebhayoloji, okuhlanganisa i-apoptosis, ukuvuvukala, kanye ne-metabolism.
