I-N-Acetyl-D-proline CAS:59785-68-1

I-N-Acetyl-D-proline ibaluleke kakhulu kumakhemikhali e-peptide njengengxenye ebalulekile yokwenziwa kwama-peptide nama-peptidomimetics. Njenge-acetylated D-proline derivative, isebenza njengendlela eguquguqukayo yokungenisa izinsalela ezithile ze-chiral kumaketanga e-peptide ngezindlela zokwenziwa kwe-peptide zesigaba esiqinile nesigaba sesisombululo. Abacwaningi kanye nosokhemisi basebenzisa i-N-Acetyl-D-proline ukwenza ngezifiso ukulandelana kwe-peptide ngokulawulwa okunembile kwe-stereochemical, okuvumela ukwakheka kwamakhemikhali amasha e-bioactive kanye nama-peptide okwelapha aqondisa ama-receptor, ama-enzyme, noma abathuthi ezinhlelweni zebhayoloji. Ngaphezu kwalokho, i-N-Acetyl-D-proline isetshenziswa njengebhloko yokwakha i-chiral ekukhiqizweni kwezidakamizwa eziphakathi, lapho i-stereochemistry yayo ehlukile ibalulekile ekuhlanganisweni kwezidakamizwa ze-chiral kanye namakhemikhali e-bioactive. I-chirality yayo kanye nokuzinza kwayo kuyenza ibe yinto ebalulekile ekukhiqizweni kwemikhiqizo yemithi, ithuthukise izakhiwo zemithi kanye nomsebenzi webhayoloji wezidakamizwa zokugcina. Ngaphezu kwalokho, i-N-Acetyl-D-proline isetshenziswa ocwaningweni lwe-biochemical ukutadisha i-proline metabolism, umsebenzi wamaprotheni, kanye ne-enzyme kinetics. Indima yayo ekucaciseni izindlela zamaseli kanye nezinqubo ze-metabolic inegalelo ekuqondeni imisebenzi ye-proline ezinhlelweni zezinto eziphilayo kanye nemiphumela yayo engaba khona empilweni nasezifweni. Ngamafuphi, i-N-Acetyl-D-proline idlala indima ebalulekile ekuthuthukiseni ucwaningo lwesayensi, intuthuko yemithi, kanye nezifundo ze-biochemical, inikeza ososayensi nochwepheshe ithuluzi elisebenziseka ngezindlela eziningi lokuhlola ukusetshenziswa okuhlukahlukene kwe-proline derivatives ekutholakaleni kwemithi, ukwenziwa kwe-peptide, kanye nophenyo lwe-biochemical.