I-AC-D-Trp-OH CAS:2280-01-5.

I-AC-D-Trp-OH ibaluleke kakhulu kumakhemikhali e-peptide njengengxenye ebalulekile yokwenziwa kwama-peptide nama-peptidomimetics. Njenge-acetylated D-tryptophan derivative, isebenza njengendlela eguquguqukayo yokungenisa izinsalela ezithile ze-chiral kumaketanga e-peptide ngokusebenzisa izindlela zokwenziwa kwe-peptide zesigaba esiqinile nesigaba sesisombululo. Abacwaningi kanye nosokhemisi basebenzisa i-AC-D-Trp-OH ukwenza ngezifiso ukulandelana kwe-peptide ngokulawula okunembile kwe-stereochemical, okuvumela ukwakheka kwamakhemikhali amasha e-bioactive kanye nama-peptide okwelapha aqondisa ama-receptor, ama-enzyme, noma abathuthi ezinhlelweni ze-biological. Ngaphezu kwalokho, i-AC-D-Trp-OH isetshenziswa njengebhloko yokwakha i-chiral ekukhiqizweni kwezidakamizwa eziphakathi, lapho i-stereochemistry yayo ehlukile ibalulekile ekuhlanganisweni kwezidakamizwa ze-chiral kanye namakhemikhali e-bioactive. I-chirality yayo kanye nokuzinza kwayo kuyenza ibe yinto ebalulekile ekukhiqizweni kwemikhiqizo yemithi, ithuthukise izakhiwo ze-pharmacological kanye nomsebenzi we-biological wezidakamizwa zokugcina. Ngaphezu kwalokho, i-AC-D-Trp-OH isetshenziswa ocwaningweni lwe-biochemical ukutadisha i-tryptophan metabolism, umsebenzi wamaprotheni, kanye ne-neurochemistry. Indima yayo ekucaciseni izindima zama-molecule atholakala ku-tryptophan ekudlulisweni kwemizwa, ukulawulwa kwemizwa, kanye ne-circadian rhythms kunegalelo ekuqondeni imiphumela yawo engaba khona ezinkingeni zemizwa kanye nezimo zengqondo. Ngamafuphi, i-AC-D-Trp-OH idlala indima ebalulekile ekuthuthukiseni ucwaningo lwesayensi, ukuthuthukiswa kwemithi, kanye nezifundo ze-biochemical, inikeza ososayensi nochwepheshe ithuluzi elisebenziseka ngezindlela eziningi lokuhlola ukusetshenziswa okuhlukahlukene kwe-tryptophan derivatives ekutholakaleni kwemithi, ukwenziwa kwe-peptide, kanye nophenyo lwe-biochemical.