H-Leu-OBzl·Tos CAS:1738-77-8

I-H-Leu-OBzl·Tos isebenza njengesakhiwo esibalulekile ekwakheni ama-peptide, idlala indima ebalulekile ekwakheni ama-peptide anezici ezithile zesakhiwo kanye nokusebenza. Ukuba khona kweqembu elivikela i-benzyl kuqinisekisa ukuthi insalela ye-leucine ihlala ingashintshiwe ngesikhathi sezinqubo zokwenziwa kwama-peptide, okuvumela ukuhlanganiswa kwama-peptide okunembile nokulawulwayo. Iqembu le-tosyl lenza kube lula ukusabela kokukhetha okuphakathi, okuvumela ukuhlanganiswa kwama-peptide aqukethe i-leucine namanye ama-molecule noma izindawo ngendlela elawulwayo. Le nhlanganisela iwusizo ekudaleni ama-peptide conjugates anezakhiwo ezithile njengokuqina okuthuthukisiwe, ukuncibilika, noma ikhono le-bioconjugation. Ngaphezu kwendima yayo ekwakhiweni kwama-peptide, i-H-Leu-OBzl·Tos ithola ukusetshenziswa ocwaningweni lwe-proteomics kanye ne-biochemical, lapho ingasetshenziswa khona ekuguqulweni kwamaprotheni endaweni ethile, ekwakhiweni kwama-peptide libraries, noma ekusebenzeni kwezindawo zokuhlola ezahlukahlukene ze-bioanalytical. Ukuguquguquka kwayo kanye nokuhambisana kwayo nezimo ezahlukahlukene zokuhlola kuyenza ibe yingxenye ebalulekile yokwembula ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Sekukonke, i-H-Leu-OBzl·Tos imelela ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide anezakhiwo ezithile kanye nokusebenza kwawo, ngaleyo ndlela enikela ekuthuthukisweni kwezokwelapha, ubuchwepheshe be-bio, kanye namasu okuhlanganisa i-bio.