H-Leu-OBut·HCl CAS:2748-02-9.

I-H-Leu-OBut·HCl idlala indima ebalulekile ekuhlanganisweni kwe-peptide yesigaba esiqinile, isebenza njengesisekelo esibalulekile sokwakhiwa kwama-peptide anokulandelana okuthile kanye nezici zesakhiwo. Abacwaningi basebenzisa le nhlanganisela ukuze kube lula ukuhlanganiswa okukhethiwe kwama-amino acid, okuvumela ukuhlanganiswa kwe-peptides eziyinkimbinkimbi ngokunemba nangokusebenza kahle. Ukuhambisana kwayo nohlu olubanzi lwe-reagents zokuhlanganisa kanye nezisekelo ze-resin kwenza kube ukukhetha okuguquguqukayo kwezinqubo zokuhlanganiswa kwe-peptide, okunikeza abacwaningi ukuguquguquka ekwenzeni ngokwezifiso amasu okuhlanganiswa ukuze kufezwe izakhiwo ze-peptide ezahlukahlukene. Ngaphezu kwalokho, i-H-Leu-OBut·HCl isetshenziswa ekuthuthukisweni kwemithi emisha esekelwe ku-peptide, lapho ikhwalithi yayo ehambisanayo kanye nokuthembeka kubalulekile ekuqinisekiseni ukuphindaphindeka kwezinqubo zokwenziwa kanye nokukhiqizwa kwemikhiqizo ye-peptide emsulwa. Ekutholakaleni nasekuthuthukisweni kwemithi, ukuhlanganiswa okunembile kwama-peptide analogs kanye nama-derivatives kubalulekile ekuhloleni ubudlelwano besakhiwo nomsebenzi kanye nokwenza ngcono izakhiwo zokwelapha. Ngakho-ke, i-H-Leu-OBut·HCl isebenza njengethuluzi eliwusizo kososayensi ababandakanyeka ekwakhiweni nasekuhlanganisweni kwamakhemikhali asekelwe ku-peptide anezicelo ezingaba khona zezokwelapha. Sekukonke, ukusebenza okubanzi kwe-H-Leu-OBut·HCl ekwakhiweni kwe-peptide kanye nokuhambisana kwayo nezinqubo ezijwayelekile zelebhu kwenza kube yingxenye ebalulekile kumathuluzi abacwaningi nosokhemisi abasebenza emikhakheni yekhemistri ephilayo, ucwaningo lwemithi, kanye nokuthuthukiswa kwemithi.