I-H-Ile-OMe·HCl CAS:18598-74-8

I-H-Ile-OMe·HCl isebenza njengesakhiwo esibalulekile ekwakheni ama-peptide, idlala indima ebalulekile ekwakheni ama-peptide anezici ezithile zesakhiwo nezokusebenza. Ukuba khona kweqembu le-methyl ester kuthonya ukusabela kwamakhemikhali kanye nokusebenzisana kwe-hydrophobic kwe-peptide, okwenza kube wusizo ekwakheni ama-peptide anokuvuleka kwe-membrane okuthuthukisiwe noma amakhono athile okukhomba. Le nhlanganisela ibalulekile ekudaleni ama-peptide anezakhiwo ezilungiselelwe njengokuqina okuthuthukisiwe, ukuncibilika, noma ukutholakala kwezinto eziphilayo, okwenza kube ithuluzi elibalulekile ekuthuthukisweni kwemithi. Ngaphezu kwendima yayo ekwakhiweni kwama-peptide, i-H-Ile-OMe·HCl ithola ukusetshenziswa ocwaningweni lwe-proteomics kanye ne-biochemical, lapho ingasetshenziswa khona ukutadisha ukusebenzisana kwamaprotheni nama-protein, ukuphenya imisebenzi ye-enzyme, nokuhlola izindlela zokubonisana kwamaseli. Izakhiwo zayo ezihlukile zivumela abacwaningi ukuthi bahlole ubunzima bezinqubo zamaseli kanye nezindlela zezifo, okunegalelo ekuthuthukisweni kokuqonda impilo kanye ne-pathology. Ukuguquguquka kanye nokuhambisana kwale nhlanganisela nezimo ezahlukahlukene zokuhlola kuyenza ibe yingxenye ebalulekile yokwembula ubunzima bezinhlelo zezinto eziphilayo kanye nokuthuthukisa ukungenelela okuqondiwe kwezimo ezahlukene zezokwelapha. Ngamafuphi, i-H-Ile-OMe·HCl imele ithuluzi eliwusizo kubacwaningi ekuhlanganisweni kwama-peptide, ekuthuthukisweni kwemithi, nasezifundweni ze-biochemical, enikeza ikhono lokulungisa ama-peptide anezakhiwo ezithile futhi ahlukanise izindlela eziyisisekelo zezinqubo zezinto eziphilayo, ngaleyo ndlela enikela ekuthuthukisweni kwezokwelapha kanye ne-biotechnology.